Bilgin, Sinan
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Bilgin, S.
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sinan.bilgin@ieu.edu.tr
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09.04. Surgical Sciences
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Former Staff
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Sustainable Development Goals
Documents
17
Citations
31
h-index
3
Documents
3
Citations
2
Scholarly Output
5
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5
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0/0
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0
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0
WoS Citation Count
2
Scopus Citation Count
5
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1
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2
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0
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0
WoS Citations per Publication
0.40
Scopus Citations per Publication
1.00
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2
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0
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5 results
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Now showing 1 - 5 of 5
Article Citation - Scopus: 3Assessment of Ophthalmic Vascular Changes in Fibromyalgia Patients Using Optical Coherence Tomography Angiography: Is There a Real Pathology?(Elsevier B.V., 2024) Talu Erten, P.; Bilgin, S.Background: Fibromyalgia (FM) is a widespread musculoskeletal pain disorder. Although the pathogenesis of fibromyalgia is unknown, central neurotransmitter systems and autonomic nervous system abnormalities may play a critical role. Today, the diagnosis is made by clinical findings, and there is no objective, confirmatory tests. Studies examining ophthalmic structures in patients with fibromyalgia using optic coherence tomography (OCT) and optic coherence tomography angiography (OCTA) sought objective evidence of both the neurodegenerative and vascular processes of the disease. In the results of these few studies, some findings of retinal and vascular density changes were found. Materials and methods: In this cross-sectional study, retinal superficial and deep vascular plexus density (SVP and DVP), choroid thickness, and choriocapillaris density were investigated in 42 patients with fibromyalgia and 42 healthy controls using OCTA. Results: 42 fibromyalgia patients, including 42 age- and gender-matched healthy controls, were enrolled in this study. Central macular thickness (CMT) was found to be significantly thinner in fibromyalgia patients than in healthy groups. Retinal SVP and DVP were evaluated. No significant differences were observed between FM patients and control subjects as regards DVP density in the macular area. However, SVP density significantly decreased in the superior and inferior quadrants of fibromyalgia patients compared to the healthy controls. There was no significant difference in choriocapillaris density and choroid thickness between the patients with fibromyalgia and the healthy group in all quadrants. Conclusion: We evaluated detailed ophthalmic vascular structures of patients with fibromyalgia using OCTA in our study. We found changes only superior and inferior quadrants of retinal superficial structures. There was no significant difference in other superficial vascular quadrants of the retina, deep vascular structures, and choriocapillaris density. On the other hand, the central macular thickness was thinner in FM patients. Therefore, these data show that the role of vascular processes in the pathogenesis of fibromyalgia is small, but thinner central macular thickness in FM may be significant as an objective finding of the disease © 2023 The AuthorsArticle Cilioretinal Artery Occlusion After Cataract and Macular Hole Surgery: A Case Report(Sage Publications Ltd, 2025) Bilgin, Sinan; Dogruya, SuzanPurpose To report cilioretinal artery occlusion in a patient undergoing cataract and macular hole surgery.Material and Method A 78-year-old male patient was operated on for a left eye cataract and tractional macular hole. The patient had no intraoperative problems and developed sudden visual loss on the 15th postoperative day. Optic coherence tomography (OCT), fundus fluorescein angiography (FFA), and optic coherence tomography angiography (OCTA) images revealed occlusion of the cilioretinal artery. After medical treatment and 20 sessions of hyperbaric oxygen therapy, the best visual acuity was 50 cmFC, the optic nerve was pale, the macula was ischemic, and the central macular thickness was 139 microns at the last eye examination.Discussion Mitigating the risk of cilioretinal artery occlusion after vitreoretinal surgery requires a comprehensive approach that addresses patient-specific factors, surgical techniques, and perioperative management.Conclusion Occlusion of the cilioretinal artery may rarely occur after cataract and macular hole surgery. Careful follow-up, early diagnosis, and prompt intervention can minimize visual loss.Article The Short-Term Influences of Paediatric Smartphone Use on the Eye(Sage Publications Ltd, 2023) Çavdar, Ercüment; Bilgin, Sinan; Çetin, OğulcanThe aim of this study is to comprehensively evaluate the effect of smartphone use on the eye. Twenty-two children, aged 8-16 years, participated in this study. A self-administered questionnaire about smartphone usage time, outdoor activities, and sleep time to obtain dry eye was applied to the child and parents. An ocular surface disease index (OSDI), tear break-up time (TBUT), blink time, autorefractometer, optical biometry, accommodation, contrast sensitivity, and optical coherence tomography tests were applied before a 5-min video watching, and during the video session we counted the complete -incomplete blinks. After video watching, we did the tests. After the tests, we again applied a 5-min video watching and after the video we tested all the parameters again, and finally, following a 5-min resting period, we tested the parameters again. We found no difference between the groups in terms of OSDI scores. Children with punctate epithelial erosions and time spent on the phone have a statistical relation. TBUT also differs statistically before and after test periods (p = .014), since complete blinks did not differ but incomplete blinks differed before and after video watching. The nearpoint of convergence also differs after video watching (p = .008) and anterior chamber depth (ACD) decreases even after the short-time video watching period. On the contrary, we did not find any effect of short-time smartphone watching on auto-keratometer values and retinal-choroidal thickness. This is the first comprehensive study on the short-term effects of smartphone on the paediatric age group. Even 10 min of smartphone can have an effect on TBUT, incomplete blinks, nearpoint of convergence break-recovery, and ACD. During this coronavirus disease 2019 pandemic, we must be mindful of the time our children spend on the phone and keep in mind that even 10 min can have ocular effects.Article The Effect of Vitamin D and Melatonin on the Ocular Tissues in Streptozotocin - Induced Diabetes Model in Rats(Verduci Publisher, 2022) Bilgin, S.; Sivrikoz, O. Nermin; Cavdar, E.; Cetin, O.OBJECTIVE: The aim of the study was to investigate the effectiveness of vitamin D and melatonin on the ocular tissues in streptozotocin (STZ)-induced diabetes. MATERIALS AND METHODS: In this study. a total of 45 male Wistar rats were randomly divided into five groups as follows: 1) non-diabetic rats (control group); 2) untreated STZ-induced diabetic rats: 3) STZ-induced diabetic rats treated with vitamin D; 4) STZ-induced diabetic rats treated with melatonin; 5) STZ-induced diabetic rats treated with the combination of vitamin D and melatonin. After six weeks of treatment, all rats were sacrificed for post-mortem analyses. Retinal and corneal samples were obtained and analyzed for glial fibrillary acidic protein (GFAP) expression. Retinal and corneal thicknesses in addition to morphological changes were assessed via hematoxylin and eosin staining. RESULTS: Untreated diabetic rats revealed retinal disorganization, atrophy, increased vascularization along with more GFAP staining. However, all the treated groups exhibited more regular retinal layers and minimal GFAP staining. Additionally, treatment groups showed more uniform corneal layers with minimal GFAP staining. CONCLUSIONS: Melatonin and vitamin D could be used as an additional complementary treatment in diabetes. Developing treatment protocols involving supplementation, as well as informing patients about the potential benefits of vitamin D and melatonin could be impactful in the treatment process of diabetes.Article Citation - WoS: 2Citation - Scopus: 2Retinal Vascular Density Change in Patients With Aortic Valve Regurgitation(Elmer Press Inc, 2023) Topaloğlu, Caner; Bilgin, SinanBackground: The aim of this study was to assess retinal vessel density in the superficial capillary plexus layer, deep capillary plexus layer and choriocapillaris plexus layer in patients with aortic valve regurgitation (AR) using optical coherence tomography angiography (OCTA).Methods: Thirty-eight healthy participants (group 1) and 38 patients with AR (group 2) were assessed for this study. Diagnosis of AR is made by transthoracic echocardiography (TTE). Severity of AR was assessed according to values in the 2014 American Heart Association/American College of Cardiology (AHA/ACC) valve guideline. Superficial capillary plexus density (SCPD), deep capillary plexus density (DCPD) and choriocapillaris plexus density (CCPD) were analyzed between groups using OCTA.Results: SCPD measurements were found to be decreased in the nasal, inferior and central regions of patients with AR (P < 0.05). DCPD measurements were found to be decreased in the nasal and inferior regions of patients with AR (P < 0.05). CCPD measurements were found to be decreased in the inferior and central regions of patients with AR (P < 0.05). In patients with AR, CCPD measurements were significantly decreased in the inferior region compared to the control group. Central macular thickness was found to be significantly decreased in the patients with AR.Conclusions: Patients with AR showed decreased flow density compared with healthy controls. Retinal perfusion measured using OCTA in patients with AR may give an idea about microperfusion.
