Taşkın, Uğur

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Taskin, U.
Taskin, Ugur
Taşkin, Uğur
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ugur.taskin@ieu.edu.tr
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09.02. Internal Sciences
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JournalCount
Arquivos brasileiros de cardiologia2
Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi1
Echocardiography1
Echocardiography-A Journal of Cardiovascular Ultrasound And Allied Techniques1
Postepy W Kardiologii Interwencyjnej1
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Now showing 1 - 6 of 6
  • Article
    Citation - WoS: 4
    Citation - Scopus: 5
    Demonstration of Subclinical Left Ventricular Electrical and Mechanical Dysfunction in Overweight Subjects by Frontal Qrs-T Angle and 3d-Speckle Tracking Echocardiography
    (Wiley, 2023) Mammadov, G.; Taşkın, Uğur; Dindaş, Ferhat; Doğduş, Mustafa
    BackgroundOverweightness is a considerable step in the process leading to obesity. There are no sufficient studies on the effect of cardiomyopathy defined in obese patients about overweight subjects. We thought that it may be useful to examine the myocardial involvement in overweight individuals electro-mechanically with more sensitive techniques before the development of obesity cardiomyopathy. AimThe aim of the present study was to demonstrate whether or not there are subclinical left ventricular (LV) electrical and mechanical dysfunctions in overweight patients using frontal QRS-T (fQRS-T) angle (electrically) and 3D-speckle tracking echocardiography (mechanically). MethodsA total of 80 overweight patients and 80 age- and sex-matched normal weight individuals were enrolled into the study. 3D-STE examinations of the patients were performed. Electrocardiographic recordings were obtained for fQRS-T angle assessment. ResultsThe LV-GLS and LV-GCS were significantly depressed in the overweight group than in the normal weight group (-14.5 & PLUSMN; 3.4 vs. -21.7 & PLUSMN; 3.6, p < .001; -15.2 & PLUSMN; 4.6 vs. -24.3 & PLUSMN; 4.8, p < .001, respectively). The fQRS-T angle was found to be increased in the overweight group (142.5 & PLUSMN; 39.2 vs. 114.7 & PLUSMN; 43.5, p = < .001). Statistically significant positive linear correlations were observed between BMI with LV-GLS, LV-GCS, and fQRS-T angle. LV-GLS and LV-GCS were found to be disrupted linearly as BMI increased (r = .718 for BMI and LV-GLS, r = .653 for BMI and LV-GCS). As BMI increased, it was found that the fQRS-T angle increased (r = .692 for BMI and fQRS-T angle). ConclusionOur results support that, overweight individuals, despite their being apparently healthy, may have subclinical LV myocardial mechanical and electrical dysfunction.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Evaluation of Left Atrial and Left Ventricular Functions With 3d Speckle-Tracking Echocardiography in Patients With Coronary Artery Tortuosity
    (John Wiley and Sons Inc, 2023) Taskin, U.; Mammadov, G.; Topaloğlu, Caner; Koyuncu, I.; Doğduş, Mustafa
    Background: Tortuosity in the coronary arteries is a very common entity encountered during angiography. The effect of coronary artery tortuosity (CAT) on the myocardium has not been completely investigated. The aim of the current study was to assess the effects of CAT on left atrial (LA) and left ventricular (LV) myocardial functions by 3D speckle-tracking echocardiography (3D-STE). Methods: Seventy-five patients with CAT and 80 age- and gender-matched controls who proved to have normal coronary angiograms (CAG) were enrolled into the study. Following CAG, the 2D images were obtained first, and then 3D images were obtained for strain analysis. Results: The LAS-r, LAS-active, and LV-GLS were significantly depressed in the CAT (+) group (p <.001, p <.001, p =.012, respectively). The multivariate regression models demonstrated that LAS-r (p <.001), LAS-active (p =.009), and LV-GLS (p =.024) were found to be independent factors predicting CAT. Conclusion: The current study is the first to focus on the assessing both LA and LV myocardial dynamics in CAT (+) patients by strain echocardiography. The results of our study support the patients with CAT may have subclinical LA and LV myocardial involvements. © 2023 Wiley Periodicals LLC.
  • Article
    Electromechanical Demonstration of Premature Ventricular Contraction-Induced Atrial Cardiomyopathy by P Wave Duration-to-Amplitude Ratio (PWDAR) and Left Atrial Strain
    (Termedia Publishing House Ltd, 2025) Dogdus, Mustafa; Okan, Taha; Taskin, Ugur; Mammadov, Ganbar; Akkaya, Bekir; Koyuncu, Ilhan; Topaloglu, Caner
    Introduction: High premature ventricular contraction (PVC) burden is known to cause atrial remodeling. P wave duration-to-amplitude ratio (PWDAR) is a new P wave index that includes both P wave duration and P wave voltage, which can be considered to effectively evaluate atrial cardiomyopathy. 3D speckle-tracking echocardiography is accepted as a valid and reliable technique for assessment of the left ventricle (LV) and left atrium (LA). Aim: In the present study, we investigated whether patients with a high PVC burden exhibit subclinical left atrial electrical and mechanical dysfunction, assessed electrically using PWDAR and mechanically using 3D-speckle tracking echocardiography. Material and methods: Seventy-five patients with PVC (PVC+) and 75 age- and gender-matched controls were enrolled in the study. Surface 12-lead standard electrocardiograms (ECGs) were recorded. Clinical characteristics and laboratory values of the patients were obtained. Conventional 2D echocardiographic and 3D-STE analyses were performed. Results: The PWDAR was significantly higher in the PVC+ group than in the control group (p < 0.001); and the LAS-r, LAS-active, and LV-GLS were significantly depressed in the PVC+ group (p < 0.001, p < 0.001, p = 0.015, respectively). The multivariate regression models demonstrated that PWDAR (p < 0.001), LAS-r (p < 0.001), LAS-active (p = 0.008), and LV-GLS (p = 0.021) were independent factors predicting PVC-induced atrial cardiomyopathy (PVC-ACMP). Conclusions: Our results revealed subclinical left atrial electrical and mechanical dysfunction in patients with a high PVC burden. PWDAR and left atrial strain parameters can predict PVC-ACMP.
  • Article
    Citation - Scopus: 1
    Ablation of Atrioventricular Nodal Reentrant Tachycardia With Focal Cryoablation, Compared With Radiofrequency Ablation: Single-Center Experience
    (2024) Topaloğlu, C.; Fici, F.; Borne, P.V.; Taşkin, U.; Dogdus, M.; Saygi, S.; Tengiz, I.
    BACKGROUND: The ablation of atrioventricular nodal reentrant tachycardia (AVNRT) with cryoablation is an alternative to radiofrequency (RF) ablation in patients due to the low risk of total atrioventricular block. An increase in early-late recurrences after cryoablation is reported as an important disadvantage. OBJECTIVES: In this study, we aimed to compare the acute procedural success and the long-term recurrence rates of patients, with AVNRT who underwent methods. METHODS: 73 patients with AVNRT were included in the study: 32 with cryoablation and 41 with RF ablation. There was no statistically significant difference between acute procedural success in methods. The ablation procedure was performed by an operator experienced in arrhythmology. The choice of RF or cryoablation was made in the electrophysiology laboratory based on the material already available during the procedure. After the procedure, the patients were evaluated every 3 months for 2 years in polyclinic control. The significance level adopted in the statistical analysis was 5%. RESULTS: The 2 groups of patients were homogeneous.
  • Article
    Citation - WoS: 1
    Ablation of Atrioventricular Nodal Reentrant Tachycardia With Focal Cryoablation, Compared With Radiofrequency Ablation: Single-Center Experience
    (Arquivos Brasileiros Cardiologia, 2024) Topaloğlu, Caner; Fici, Francesco; Van de Borne, Philippe; Taşkın, Uğur; Doğduş, Mustafa; Saygı, Serkan; Tengiz, İstemihan
    Background: The ablation of atrioventricular nodal reentrant tachycardia (AVNRT) with cryoablation is an alternative to radiofrequency (RF) ablation in patients due to the low risk of total atrioventricular block. An increase in early-late recurrences after cryoablation is reported as an important disadvantage. Objectives: In this study, we aimed to compare the acute procedural success and the long-term recurrence rates of patients, with AVNRT who underwent methods. Methods: 73 patients with AVNRT were included in the study: 32 with cryoablation and 41 with RF ablation. There was no statistically significant difference between acute procedural success in methods. The ablation procedure was performed by an operator experienced in arrhythmology. The choice of RF or cryoablation was made in the electrophysiology laboratory based on the material already available during the procedure. After the procedure, the patients were evaluated every 3 months for 2 years in polyclinic control. The significance level adopted in the statistical analysis was 5%. Results: The 2 groups of patients were homogeneous. The fluoroscopy time (p<0.001) was shorter, but atrium-his (p=0.004) and his-ventricular (p=0.015) times were longer in the cryoablation group. There was no significant difference, in terms of acute procedural success, post-procedure jump without a single echo, and presence of echo and jump. Conclusions: Cryoablation requires less fluoroscopy time and is a safe non-inferior alternative to RF ablation in patients with AVNRT. The risk of AV block is a significant problem with the use of RF energy, making it less suitable for use in young and physically active patients.
  • Article
    Obstrüktif Koroner Arter Hastalığı ile Serum 25-oh Vitamin D, Fetuin-a, Matrix Gla Protein ve Adma Düzeyleri Arasındaki İlişki
    (2022) Tıkız, Hakan; Taşkın, Uğur
    Giriş ve Amaç: Bu çalışmada ateroskleroz etyolojisinde rol oynadığı ileri sürülen 25OH-vitamin D, Matrix Gla Protein (MGP), Fetuin-A, Asimetrik Dimetil Arjinin (ADMA) belirteçleri ile koroner arter hastalığı arasındaki ilişki araştırıldı. Gereç ve Yöntemler: Bu amaçla çalışmaya koroner arter hastalığı ön tanısı ile koroner anjiyografi işlemi uygulanmış olan ve normal koroner arter saptanan 40 olgu ile, en az bir koroner arterinde %70 ve üzerinde darlık saptanan 40 olgu olmak üzere toplam 80 olgu dahil edildi. Bulgular: Kan MGP düzeyleri koroner arter hastalığı olan grupta kontrol grubuna kıyasla anlamlı olarak yüksek olarak gözlenirken (sırasıyla 2082,79±329,75 pg/ml ve 1853,42±285,82 pg/ml, p=0,001), Fetuin-A düzeylerinin kontrol grubunda, koroner arter hastalığı grubuna kıyasla anlamlı derecede düşük olduğu gözlendi (sırasıyla 60,54±28,61 ng/ml ve 78,61±20,45 ng/ml, p=0,002). Her iki gruptaki hastaların %85’inde 25OH-vitamin D seviyeleri düşük düzeylerde izlenmekle beraber, her iki grup arasında istatistiksel olarak anlamlı olarak fark saptanmadı (sırasıyla 20,27±12,65 ng/ml ve 20,64±7,32 ng/ml, p=0,875). Kan ADMA seviyeleri incelendiğinde ise yine gruplar arasında istatistiksel olarak anlamlı bir fark gözlenmedi (grup 1; 0,099±0,053 umol/l ve grup 2; 0,089±0,051 umol/l, p>0,05). Sonuç olarak; 25OH-vitamin D ve ADMA değerleri ile koroner arter hastalığı arasında anlamlı bir ilişki saptanmazken, MGP ve Fetuin-A'nın tıkayıcı koroner arter hastalığında belirteç olabileceği gözlendi. Sonuç: Bizim çalışmamızda tıkayıcı koroner arter hastalığı tanısında MGP ve Fetuin-A biyobelirteçlerinin yol gösterici olduğu gözlenmiştir. Bu bulgular ışığında MGP ve Fetuin-A düzeylerinin koroner arter hastalığı tanısında kullanımının değerlendirilmesi için benzer altyapılı ve daha geniş popülasyonlarla yapılacak yeni çalışmalara ihtiyaç vardır.