Poyraz, T.Varol, A.Uysal, ArmağanUysal, Hasan Armağan2023-12-262023-12-2620231300-06671309-4866https://doi.org/10.29399/npa.28205https://hdl.handle.net/20.500.14365/5016Ocular flutter (OF) is a rare oculomotor syndrome. The most common etiologies are paraneoplastic, postinfectious and toxic-metabolic. However post-vaccinal etiology was rarely reported in OF. Here, we reported a post-vaccinal clinical syndrome characterized by OF-myoclonus and ataxia associated with oligoclonal bands (OCBs). A 60-year-old male who presented with dizziness, unsteady gait, involuntary movements, involuntary conjugate eye oscillations and extremity jerks that started 3 days after the second dose of mRNA BNT162b2 Covid-19 vaccine. Routine biochemical and serological analysis were within normal limits. No pathological finding was detected in brain MRI. Paraneoplastic and autoimmune encephalitis tests were unremarkable in cerebrospinal fluid (CSF). Oligoclonal bands were positive in CSF. This is the first description of the relationship between vaccines against SARS-CoV-2 and the clinical syndrome of OF, Myoclonus and Ataxia (OFMAS). Humoral immune mechanisms seem to play an important role in OFMAS. Presence of OCBs in CSF may also be associated with this condition. © 2022 by Turkish Association of Neuropsychiatry.eninfo:eu-repo/semantics/closedAccessAtaxiamyoclonusocular flutteroligoclonal bandsSARS-CoV-2vaccineantibodyclonazepamganglioside antibodyganglioside GD 1aganglioside GD 1bganglioside GM1 antibodyganglioside GM2 antibodyganglioside GM3 antibodyganglioside GQ 1b antibodyglucoseimmunoglobulinimmunoglobulin Gimmunoglobulin Mlactic acidmethylprednisoloneoligoclonal bandtozinameranunclassified drugvalproic acidadultanxietyArticleataxiabilateral kinetic tremorbreathing disordercase reportcerebrospinal fluid analysisclinical articlecoronavirus disease 2019diffusion weighted imagingdizzinesselectroneuromyographyelectrooculographyhumanhyperproteinorrhachiahypoventilationinsomniainvoluntary movementlumbar puncturemalemiddle agedmyoclonusnon insulin dependent diabetes mellitusnuclear magnetic resonance imagingobesityocular flutterpolyneuropathyprotein cerebrospinal fluid levelsaccadic eye movementsensorimotor polyneuropathytremorunsteady gaitArticle10.29399/npa.282052-s2.0-85178939458