Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14365/3610
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dc.contributor.authorDoluca, Osman-
dc.date.accessioned2023-06-16T15:00:56Z-
dc.date.available2023-06-16T15:00:56Z-
dc.date.issued2018-
dc.identifier.isbn9.78154E+12-
dc.identifier.urihttps://doi.org/10.1109/SIU.2018.8404537-
dc.identifier.urihttps://hdl.handle.net/20.500.14365/3610-
dc.descriptionAselsan;et al.;Huawei;IEEE Signal Processing Society;IEEE Turkey Section;Netasen_US
dc.description26th IEEE Signal Processing and Communications Applications Conference, SIU 2018 -- 2 May 2018 through 5 May 2018 -- 137780en_US
dc.description.abstractAs a secondary structure of DNA, G-quadruplexes are formed by folding of genomic DNA so that four repetitive guanine tracts are brought together. Some of these structures are shown to have significant role on gene regulation, however, detecting G-quadruplex formation by genomic DNA presents a significant obstacle as the these structures are easily affected by harsh experimental conditions. Instead, it is shown that prediction of these secondary structures is possible through analysis of the DNA sequence. However, the most commonly used algorithm was shown to miss two types of imperfect G-quadruplexes (i) with bulges or mismatches in the guanine-repeats, and also ones (ii) with an extraordinarily long loop. Here, we present a tool for the detection of these structures including such rudimentary but possible G-quadruplexes using G4Catchall, improving the overall prediction efficiency. © 2018 IEEE.en_US
dc.language.isotren_US
dc.publisherInstitute of Electrical and Electronics Engineers Inc.en_US
dc.relation.ispartof26th IEEE Signal Processing and Communications Applications Conference, SIU 2018en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectG-quadruplexen_US
dc.subjectGenomicsen_US
dc.subjectMotif predictionen_US
dc.subjectPythonen_US
dc.subjectRegular expressionen_US
dc.subjectDNAen_US
dc.subjectDNA sequencesen_US
dc.subjectForecastingen_US
dc.subjectGenesen_US
dc.subjectPositive ionsen_US
dc.subjectExperimental conditionsen_US
dc.subjectG-quadruplexesen_US
dc.subjectGenomic DNAen_US
dc.subjectGenomicsen_US
dc.subjectGuanine-tractsen_US
dc.subjectPythonen_US
dc.subjectRegular expressionsen_US
dc.subjectSecondary structuresen_US
dc.subjectSignal processingen_US
dc.titleRelaxed formation rules for G-quadruplex predictionen_US
dc.title.alternativeEsnek kurallar ile g-dörtlüsü tahminien_US
dc.typeConference Objecten_US
dc.identifier.doi10.1109/SIU.2018.8404537-
dc.identifier.scopus2-s2.0-85050822736en_US
dc.authorscopusid36056081300-
dc.identifier.startpage1en_US
dc.identifier.endpage4en_US
dc.identifier.wosWOS:000511448500390en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityN/A-
dc.identifier.wosqualityN/A-
item.grantfulltextreserved-
item.openairetypeConference Object-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.languageiso639-1tr-
item.cerifentitytypePublications-
crisitem.author.dept05.02. Biomedical Engineering-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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