Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14365/5213
Title: Ocular Flutter-Myoclonus-Ataxia Syndrome After mRNA BNT162b2 COVID-19 Vaccine: A Case Report
Authors: Poyraz, Turan
Varol, Armagan
Uysal, Armağan
Keywords: Ataxia
myoclonus
ocular flutter
oligoclonal bands
SARS-CoV-2
vaccine
Publisher: Turkısh Neuropsychıatry Assoc-Turk Noropsıkıyatrı Dernegı
Abstract: Ocular flutter (OF) is a rare oculomotor syndrome. The most common etiologies are paraneoplastic, postinfectious and toxic-metabolic. However post-vaccinal etiology was rarely reported in OF. Here, we reported a post-vaccinal clinical syndrome characterized by OF-myoclonus and ataxia associated with oligoclonal bands (OCBs).A 60-year-old male who presented with dizziness, unsteady gait, involuntary tremors, involuntary conjugate eye oscillations and extremity jerks that started 3 days after the second dose of mRNA BNT162b2 Covid-19 vaccine. Routine biochemical and serological analysis were within normal limits. No pathological finding was detected in Brain MRI.Paraneoplastic and autoimmune encephalitis tests were unremarkable in cerebrospinal fluid (CSF). Oligoclonal bands were positive in CSF. This is the first description of the relationship between vaccines against SARS-CoV-2 and the clinical syndrome of OF, Myoclonus and Ataxia (OFMAS). Humoral immune mechanisms seem to play an important role in OFMAS. Presence of OCBs in CSF may also be associated with this condition.
URI: https://hdl.handle.net/20.500.14365/5213
ISSN: 1300-0667
1309-4866
Appears in Collections:WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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