Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14365/5478
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kurul, F. | - |
dc.contributor.author | Avci, M.B. | - |
dc.contributor.author | Yaman, S. | - |
dc.contributor.author | Topkaya, S.N. | - |
dc.contributor.author | Cetin, A.E. | - |
dc.date.accessioned | 2024-08-25T15:14:07Z | - |
dc.date.available | 2024-08-25T15:14:07Z | - |
dc.date.issued | 2024 | - |
dc.identifier.isbn | 978-151067334-2 | - |
dc.identifier.issn | 0277-786X | - |
dc.identifier.uri | https://doi.org/10.1117/12.3025745 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14365/5478 | - |
dc.description | The Society of Photo-Optical Instrumentation Engineers (SPIE) | en_US |
dc.description | Biophotonics in Point-of-Care III 2024 -- 10 April 2024 through 12 April 2024 -- Strasbourg -- 200984 | en_US |
dc.description.abstract | Compact and portable biosensing technologies play an important role in replacing traditional counterparts that require costly and heavy equipment, as well as complex infrastructure. The integration of these easy-to-use and cheap devices allows for the conducting of biosensing analyses in resource-limited settings. The study produced a portable optofluidic platform that is lightweight (260 g) and compact (16 cm×10 cm×11 cm). It combines subwavelength nanohole arrays, microfluidics technology, and on-chip computational imaging. It records plasmonic diffraction field images with a CMOS imager and an LED light, allowing for a large field of view for refractive index measurement. This LED source generates diffraction patterns on the imager. The microfluidic pump confirms accurate analyte delivery, allowing real-time analysis of diffraction field images to reveal time-dependent binding kinetics of biomolecules. It identifies biomolecular interactions without labelling, allowing for the detection and quantification of biomolecules. Our platform has an outstanding limit-of-detection (LOD) of 5ng/mL for label-free detection of protein IgG. We effectively determined the association and dissociation constants for protein A/G and IgG binding using real-time diffraction field images. The optofluidic biosensor platform is ideal for surface plasmon resonance (SPR) in field applications. It can monitor interactions in real-time, making it useful for studying the way various biological and chemical compounds bind in many areas. © 2024 SPIE. | en_US |
dc.description.sponsorship | Council of Turkey; TUBITAK, (118C458) | en_US |
dc.language.iso | en | en_US |
dc.publisher | SPIE | en_US |
dc.relation.ispartof | Proceedings of SPIE - The International Society for Optical Engineering | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Computational imaging | en_US |
dc.subject | Label-free biosensing | en_US |
dc.subject | Microfluidics | en_US |
dc.subject | Plasmonics | en_US |
dc.subject | Computational Imaging | en_US |
dc.subject | Diffraction | en_US |
dc.subject | Dissociation | en_US |
dc.subject | Light emitting diodes | en_US |
dc.subject | Microfluidics | en_US |
dc.subject | Plasmonics | en_US |
dc.subject | Proteins | en_US |
dc.subject | Refractive index | en_US |
dc.subject | Surface plasmon resonance | en_US |
dc.subject | Biosensing | en_US |
dc.subject | Computational imaging | en_US |
dc.subject | Diffraction fields | en_US |
dc.subject | Dynamic binding | en_US |
dc.subject | Field images | en_US |
dc.subject | In-field | en_US |
dc.subject | Label-free biosensing | en_US |
dc.subject | Optofluidic devices | en_US |
dc.subject | Plasmonics | en_US |
dc.subject | Real- time | en_US |
dc.subject | Biomolecules | en_US |
dc.title | Portable Optofluidic Device for Dynamic Binding Analysis in Field-Settings | en_US |
dc.type | Conference Object | en_US |
dc.identifier.doi | 10.1117/12.3025745 | - |
dc.identifier.scopus | 2-s2.0-85199071516 | en_US |
dc.department | İzmir Ekonomi Üniversitesi | en_US |
dc.authorscopusid | 58617032100 | - |
dc.authorscopusid | 58242821000 | - |
dc.authorscopusid | 57188820254 | - |
dc.authorscopusid | 36612616900 | - |
dc.authorscopusid | 35291427500 | - |
dc.identifier.volume | 13008 | en_US |
dc.identifier.wos | WOS:001269116400027 | en_US |
dc.institutionauthor | … | - |
dc.relation.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q4 | - |
dc.identifier.wosquality | N/A | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Conference Object | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
CORE Recommender
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.