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https://hdl.handle.net/20.500.14365/5554
Title: | 25-Hydroxyvitamin Levels in Sjögren's Syndrome: Is It the Right Time To Dismiss the Case or Not? |
Authors: | Karabulut, Gonca Yılmaz, Zevcet Yıldırım Şimşir, İlgin Barutcuoğlu, Burcu Tanıgör, Göksel |
Keywords: | 25 OH-D3 levels disease activity sj & ouml;gren syndrome Vitamin D Primary Sjogrens-Syndrome Vitamin-D Levels Disease-Activity Association Deficiency Essdai |
Publisher: | Walter De Gruyter Gmbh |
Abstract: | Objectives: This study aimed to investigate whether patients with Primary Sjogren Syndrome (SjS) have different levels of 25 OH-D3 (Vitamin D) when compared to healthy populations and whether differences in 25 OH-D3 correlated with disease activity or markers. Methods: Eighty-eight female patients with SjS and 3,338 age-matched healthy female controls were included in this study. 25 OH-D3 levels were compared with healthy controls. Then the patients were stratified according to their 25 OH-D3 levels, either insufficient/deficient or normal (<50 nmol/L or >= 50 nmol/L). The disease activity was evaluated using The EULAR Sjogren's syndrome (SS) disease activity index (ESSDAI) and its components. Correlation analyses were also performed for a possible correlation with disease characteristics and markers of activity. Results: No differences in 25 OH-D3 levels were found between SjS and healthy populations (p>0.05). No correlations were found between patient characteristics or laboratory values (p>0.05). Conclusions: This study did not find a link between disease characteristics and disease activity and 25 OH-D3 levels. Prospective studies with more patients should be conducted to reach a conclusion. |
URI: | https://doi.org/10.1515/tjb-2023-0273 https://hdl.handle.net/20.500.14365/5554 |
ISSN: | 0250-4685 1303-829X |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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