Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14365/5554
Title: 25-Hydroxyvitamin-D levels in Sjögren's syndrome: is it the right time to dismiss the case or not?
Authors: Karabulut, Gonca
Yılmaz, Zevcet
Yıldırım Şimşir, İlgin
Barutcuoğlu, Burcu
Tanıgör, Göksel
Keywords: 25 OH-D3 levels
disease activity
sj & ouml;gren syndrome
Vitamin D
Primary Sjogrens-Syndrome
Vitamin-D Levels
Disease-Activity
Association
Deficiency
Essdai
Publisher: Walter De Gruyter Gmbh
Abstract: Objectives: This study aimed to investigate whether patients with Primary Sjogren Syndrome (SjS) have different levels of 25 OH-D3 (Vitamin D) when compared to healthy populations and whether differences in 25 OH-D3 correlated with disease activity or markers. Methods: Eighty-eight female patients with SjS and 3,338 age-matched healthy female controls were included in this study. 25 OH-D3 levels were compared with healthy controls. Then the patients were stratified according to their 25 OH-D3 levels, either insufficient/deficient or normal (<50 nmol/L or >= 50 nmol/L). The disease activity was evaluated using The EULAR Sjogren's syndrome (SS) disease activity index (ESSDAI) and its components. Correlation analyses were also performed for a possible correlation with disease characteristics and markers of activity. Results: No differences in 25 OH-D3 levels were found between SjS and healthy populations (p>0.05). No correlations were found between patient characteristics or laboratory values (p>0.05). Conclusions: This study did not find a link between disease characteristics and disease activity and 25 OH-D3 levels. Prospective studies with more patients should be conducted to reach a conclusion.
URI: https://doi.org/10.1515/tjb-2023-0273
https://hdl.handle.net/20.500.14365/5554
ISSN: 0250-4685
1303-829X
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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