Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14365/778
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dc.contributor.authorHarmancı, Duygu-
dc.contributor.authorUygun, Zihni Onur-
dc.contributor.authorSezgin, Ayse Kocak-
dc.contributor.authorDemirdover, Cenk-
dc.contributor.authorSagin, Ferhan Girgin-
dc.contributor.authorAkdogan, Gul-
dc.date.accessioned2023-06-16T12:47:33Z-
dc.date.available2023-06-16T12:47:33Z-
dc.date.issued2020-
dc.identifier.issn1040-0397-
dc.identifier.issn1521-4109-
dc.identifier.urihttps://doi.org/10.1002/elan.202060264-
dc.identifier.urihttps://hdl.handle.net/20.500.14365/778-
dc.description.abstractIn this study, for the first time in literature, an impedimetric biosensor technology was developed to determine Heat Shock Protein-47 (HSP-47) for the characterization of primary skin fibroblast cells. Gold nanoparticle electrodes (GNPE) were modified with amino-functionalized graphene oxide layers and anti-HSP-47 were immobilized on this layer. The performance of the biosensor was tested with real samples as cell lysates. The low detection limit (LOD) and the linear detection limit (LOQ) of the biosensor were calculated as 9.47 pg/mL and 3.23 pg/mL, respectively. Linear measurement range was obtained between 10-160 pg/mL HSP-47. The reproducibility of the biosensor was good.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TuBTAK) [118S595]en_US
dc.description.sponsorshipWe are grateful to thank The Scientific and Technological Research Council of Turkey (TuBTAK) for supporting our TuBTAK-1005 project with the project number of 118S595.en_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofElectroanalysısen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHSP-47en_US
dc.subjectimpedanceen_US
dc.subjectgold nanoparticleen_US
dc.subjectgrapheneen_US
dc.subjectchronoimpedanceen_US
dc.subjectHsp47en_US
dc.titleRapid Fibroblast Cell Culture Characterization with Impedimetric Label-free Heat Shock Protein-47 Biosensoren_US
dc.typeArticleen_US
dc.identifier.doi10.1002/elan.202060264-
dc.identifier.scopus2-s2.0-85088816714en_US
dc.departmentİzmir Ekonomi Üniversitesien_US
dc.authoridKocak, Ayse/0000-0002-1510-2937-
dc.authoriduygun, zihni onur/0000-0001-9045-7271-
dc.authoriddemirdover, cenk/0000-0001-8387-5096-
dc.authorwosidKocak, Ayse/AAZ-7831-2020-
dc.authorwosiduygun, zihni onur/P-8783-2015-
dc.authorwosiddemirdover, cenk/J-6211-2013-
dc.authorscopusid55935858800-
dc.authorscopusid51566114200-
dc.authorscopusid57196089710-
dc.authorscopusid6506957896-
dc.authorscopusid15044198200-
dc.authorscopusid55936538800-
dc.identifier.volume32en_US
dc.identifier.issue10en_US
dc.identifier.startpage2310en_US
dc.identifier.endpage2315en_US
dc.identifier.wosWOS:000553463300001en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ2-
dc.identifier.wosqualityQ2-
item.grantfulltextembargo_20300101-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextWith Fulltext-
item.languageiso639-1en-
crisitem.author.dept09.01. Basic Medical Sciences-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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