Browsing by Author "Alpaydin, Aylin Ozgen"

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Citation - Scopus: 1
Clinical Outcomes of Male Subjects With Moderate Copd Based on Maximum Mid-Expiratory Flow
(Daedalus Enterprises Inc, 2021) Aktan, Ridvan; Ozalevli, Sevgi; Alpaydin, Aylin Ozgen
BACKGROUND: Although FEV1 and FEV1/NVC are accepted as standard parameters in treatment follow-up, these parameters have a limited ability to predict clinical outcomes in patients with COPD. However, small airways dysfunction, which is determined by maximum mid-expiratory flow, is variable in the same stage of patients with COPD, even if their FEV1 and FEV1/FVC are similar. The aim of this study was to compare pulmonary function, the severity of perceived dyspnea, the severity of fatigue, physical activity level, and health-related quality of life based on the severity of small airways dysfunction in male subjects with moderate COPD. METHODS: The study consisted of 96 subjects with moderate COPD. Pulmonary function tests, the distance achieved on the 6-min walk test, the modified Medical Research Council Dyspnea Scale, the International Physical Activity Questionnaire - short form, the Fatigue Severity Scale, the St George Respiratory Questionnaire, and Short Form 36 questionnaire were evaluated in all subjects. After calculating the mean percent of predicted maximum mid-expiratory flow for the entire sample, subjects were divided into 2 groups: below average (Group 1, n = 54 subjects) and above average (Group 2, n = 42 subjects). RESULTS: There were no differences between the groups in age, body mass index, cigarette consumption, percent of predicted FEV1, and FEV1/FVC (P = .55, .61, .19, .09, and .15, respectively). Scores from the Fatigue Severity Scale and the modified Medical Research Council dyspnea scale were significantly higher in Group 1 (P = .003 and P = .002, respectively); in addition, results from the 6-min walk test and the International Physical Activity Questionnaire - short form scores were significantly lower (P = .001 and P < .001, respectively). CONCLUSIONS: Increased small airways dysfunction led to increased perception of dyspnea and fatigue, as well as poor exercise capacity and health-related quality of life in male subjects with COPD. We suggest that it may be useful to consider the maximum mid-expiratory flow in addition to FEV1 and FEV1/FVC in the treatment and follow-up of male patients with moderate COPD.
Citation - WoS: 1
Citation - Scopus: 4
The Effects of Inspiratory Muscle Warm-Up Prior To Inspiratory Muscle Training During Pulmonary Rehabilitation in Subjects With Chronic Obstructive Pulmonary Disease: a Randomized Trial
(Taylor & Francis Inc, 2025) Aktan, Rıdvan; Özalevli, Sevgi; Yakut, Hazal; Alpaydin, Aylin Ozgen
Background: While a whole-body warm-up may not adequately prepare the inspiratory muscles for exercise, inspiratory warm-up is an effective approach in preparing the inspiratory muscles for exertion.Objectives: To investigate the effects of inspiratory muscle warm-up performed prior to inspiratory muscle training (IMT) during pulmonary rehabilitation (PR) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) and inspiratory muscle weakness.Methods: Pulmonary function tests, maximal inspiratory and expiratory pressures (MIP and MEP), 6-minute walk test distance (6MWD), modified Medical Research Council Dyspnea Scale(mMRC), St. George's respiratory questionnaire and the 36-item short-form health survey were evaluated. Both groups performed IMT during PR for 8 weeks. The warm-up group (n = 15), in addition to the standard IMT group (n = 15), performed an inspiratory muscle warm-up protocol before each IMT session.Results: At the end of the 8-week intervention, improvements in dyspnea (mMRC in score, p =0.033, effect size =0.76); exercise capacity (6MWD in meters, p =0.001, effect size =1.30); pulmonary function [forced expiratory volume in 1 second (FEV1) in %predicted, p =0.006, effect size =1.10]; and inspiratory muscle strength (MIP in cmH(2)O, p =0.001, effect siz e = 1.35) were significantly greater in the warm-up group. Moreover, there were significant improvements in health-related quality of life (HRQoL) sub-scores after the training in both groups (p <0.05).Conclusions: This study demonstrated improvements in both groups, surpassing or closely approaching the established minimal clinically important difference values for the respective outcomes. Performing a warm-up for inspiratory muscles before IMT boosts benefits for pulmonary function, inspiratory muscle strength, exercise capacity, dyspnea, and HRQoL in subjects with moderate-to-severe COPD and inspiratory muscle weakness.
The Effects of Inspiratory Muscle Warm-Up Prior To Inspiratory Muscle Training During Pulmonary Rehabilitation in Subjects With Copd
(European Respiratory Soc Journals Ltd, 2021) Aktan, Ridvan; Ozalevli, Sevgi; Yakut, Hazal; Alpaydin, Aylin Ozgen
[Abstract Not Available]
Citation - WoS: 15
Citation - Scopus: 18
Effects of Supervised Exercise Program and Home Exercise Program in Patients With Systemic Sclerosis: a Randomized Controlled Trial
(Wiley, 2021) Yakut, Hazal; Ozalevli, Sevgi; Aktan, Ridvan; Alpaydin, Aylin Ozgen; Birlik, Ahmet Merih; Can, Gercek
Aim To compare the effects of supervised exercise and home exercise program in patients with systemic sclerosis (SSc). Methods Thirty-seven SSc patients were included. Patients with SSc were allocated into 2 groups as supervised and home exercise. Breathing, aerobic and resistance exercises were performed with a physiotherapist for 12 weeks in the supervised exercise group. Breathing, posture and aerobic exercises were given to the home exercise group as a home program for 12 weeks. All patients were assessed at baseline and 12 weeks later in terms of functional capacity, pulmonary functions, respiratory-peripheral muscle strength, dyspnea severity, health-related quality of life (HRQoL) and fatigue level. Results Significant improvements were observed in the functional capacity, measured by 6 minute walking test in the supervised exercise group (before = 376.21 +/- 65.50, after = 518.78 +/- 75.84 m) and home exercise group (before = 384.44 +/- 68.14, after = 432.7 +/- 70.8 m; (P < .05). Respiratory-peripheral muscle strength (with the exception of inspiratory muscle strength and upper limb strength in the home exercise group) and HRQoL were significantly increased and fatigue level was significantly decreased in the supervised exercise and home exercise groups (P < .05). However, pulmonary functions and dyspnea severity were significantly improved only in the supervised exercise group (P < .05). The supervised exercise program was found superior to the home exercise program for change in all parameters (P < .05). Conclusion This study suggests that exercise interventions should be applied in addition to the medical treatments of patients with SSc as supervised and home exercise programs play an important role in the functionality and health status of these patients.
Factors That Affect the Severity of Fatigue in Patients With Copd
(European Respiratory Soc Journals Ltd, 2020) Alpaydin, Aylin Ozgen; Aktan, Ridvan; Keles, Elvan; Ozalevli, Sevgi
[Abstract Not Available]
Is It More Effective to Begin with Inspiratory Muscle Warm-Up Before Inspiratory Muscle Training in COPD Patients? Preliminary Findings of a Randomized Controlled Trial
(European Respiratory Soc Journals Ltd, 2020) Aktan, Ridvan; Ozalevli, Sevgi; Alpaydin, Aylin Ozgen
KOAH Hastalarında Vücut Ağırlığı-Yürüme Mesafesinin Sağlıkla İlişkili Yaşam Kalitesi İle İlişkisi: 6 Dakikalık Yürüme Mesafesi İle Karşılaştırmalı Bir Çalışma
(2025) Aktan, Rıdvan; Alpaydin, Aylin Ozgen; Ozalevli, Sevgi
Amaç: Bu çalışmanın amacı, geliştirilmiş bir sonuç ölçütü olarak 6 dakika yürüme testi mesafesi-vücut ağırlığı çarpımı (yani 6 dakikalık yürüme işi-6DK-İŞİ) ile sağlıkla ilişkili yaşam kalitesi arasındaki ilişkiyi incelemek ve bu ilişkiyi 6 dakika yürüme testi mesafesi ile karşılaştırmaktı. Yöntem: Bu retrospektif kesitsel çalışmaya orta-ağır KOAH'lı toplam 81 hasta (ortalama yaş: 61.0±4.6 yıl) dahil edildi. Çalışma Ocak 2025 ile Mart 2025 tarihleri arasında gerçekleştirildi. Hastaların klinik özellikleri, akciğer fonksiyon testleri, 6 dakika yürüme testi mesafeleri ve Saint George Solunum Anketi (SGRQ) ile ölçülen sağlıkla ilişkili yaşam kalitesi sonuçları kaydedildi. 6DK-İŞİ, 6 dakika yürüme testi mesafesi ve vücut ağırlığının birbiriyle çarpımı olarak hesaplandı ve kg.metre (kg.m) olarak kaydedildi. SGRQ ile 6 dakika yürüme testi mesafesi ve 6DK-İŞİ arasındaki korelasyon katsayıları ve basit doğrusal regresyonlar değerlendirildi. Bulgular: Hastaların ortalama 6 dakika yürüme testi mesafesi ve 6DK- İŞİ sırasıyla 441.5±83.3 m ve 33176.2±9865.8 kg.m idi. 6DK-İŞİ SGRQ alt alanlarıyla (r=−.582 ile −.641 arasında, p<.001) 6 dakika yürüme testi mesafesine (r =−.381 ile −.455 arasında, p<.001) kıyasla daha güçlü korelasyonlar gösterdi. Ayrıca basit doğrusal regresyon analizine göre, SGRQ toplam puanı ile 6 dakika yürüme testi mesafesi arasındaki belirleme katsayısı (R2) .207 iken 6DK-İŞİ ise .411 idi. Sonuç: Bulgularımız 6 dakika yürüme testinde kat edilen basit mesafe yerine 6DK-İŞİ’nin kullanılmasının, yaşam kalitesi ile ilişkisi nedeniyle orta-ağır KOAH'lı hastalarda daha avantajlı olduğunu göstermektedir. Bu nedenle 6DK-İŞİ orta-ağır KOAH'lı hastalarda fonksiyonel kapasiteyi tahmin etmek için daha etkili bir sonuç parametresi olabilir. Daha geniş, daha çeşitli popülasyonlarla ve uzunlamasına tasarımlarlı gelecek çalışmalara ihtiyaç vardır.
Citation - WoS: 1
The Relationships Between the Fear of Covid-19 and Perceived Stress and Dyspnea During the Covid-19 Pandemic in Patients With Copd: Preliminary Findings of a Prospective Study
(European Respiratory Soc Journals Ltd, 2021) Aktan, Ridvan; Ozalevli, Sevgi; Yakut, Hazal; Alkan, Busra; Alpaydin, Aylin Ozgen
[Abstract Not Available]
Should Maximal Mid-Expiratory Flow (mmef) Be Considered More in Copd?
(European Respiratory Soc Journals Ltd, 2020) Aktan, Ridvan; Ozalevli, Sevgi; Alpaydin, Aylin Ozgen
[Abstract Not Available]
Citation - WoS: 2
Validation of the Rapid Assessment of Physical Activity Questionnaire in Older Patients With Chronic Obstructive Pulmonary Disease
(Dokuz Eylul Univ Inst Health Sciences, 2021) Aktan, Ridvan; Ozalevli, Sevgi; Yalcinkaya, Gamze; Alpaydin, Aylin Ozgen; Sevinc, Can
Purpose: There are not many questionnaires that have proven validity and reliability in evaluating the level of physical activity in older patients with chronic obstructive pulmonary disease (COPD). In clinical and scientific studies, it is important to quickly determine the physical activity level of patients in terms of time management. The aim of the study was to examine the validity of the rapid assessment of physical activity (RAPA) questionnaire in older patients with COPD. Methods: A total of 105 older patients with COPD surveyed the short form of the International Physical Activity Questionnaire (IPAQ-SF) and after 2 weeks RAPA questionnaire as well. The IPAQ-SF was accepted as the gold standard for physical activity assessment in COPD. Furthermore, patients were assessed for a 6-min walking test (6MWT) and perceived dyspnea (with modified medical research dyspnea scale (mMRC)). Correlation coefficients (r) was used for the relationship between RAPA and IPAQ-SF. Results: There were significant positive correlations between RAPA and IPAQ-SF total score (r = 0.968, p<0.001), 6MWT (r = 0.626, p<0.001), in addition to significant negative correlation between the RAPA and mMRC scores (r = -0.454, p<0.001). The RAPA showed good sensitivity (87.5%) and a specificity (100%) value. Positive and negative predictive values of the RAPA were 100% and 96.4% respectively. Conclusion: This study showed the RAPA was an easy-to-use, valid, and reliable questionnaire to measure physical activity levels in older patients with COPD.