Browsing by Author "Bayrak, Feda"

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    Article
    Comparative Survival Function in Patients With Positive Surgical Margins Following Laryngectomy
    (Springer India, 2023) Özkul, Yılmaz; Ciğer, Ejder; Balci, Mustafa Koray; Kılavuz, Ahmet Erdem; Bayrak, Feda; Songu, Murat; İşlek, Akif
    Aims: This study aims to make a comparative analysis of disease-free survival (DFS) and overall disease-specific survival (OS) in patients with laryngeal carcinoma. Materials and methods: The study was designed retrospectively. Sixteen patients with postoperative PSM and 30 with negative surgical margins (NSM) were included. Survival analysis and Long-Rank comparisons was performed for DFS and OS between groups. Results: PSM was a significant independent risk factor for loco-regional recurrence and disease-related mortality (p = 0.004, HR: 1.6, p = 0.002, HR: 3.2, respectively). DFS and OS were significantly longer in NSM group (p = 0.001 and 0.003, respectively). For PSM group, 2- and 5-year DFS rates were 57%; OS rates were 80% and 34% respectively. In NSM group, 2- and 5-year DFS rates were 96% and 83%; OS rates were found to be 96%. Conclusion: PSM had significant relation with poor prognosis.