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Browsing by Author "Ekin, Atalay"

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    24 Saatlik İdrarda Protein Atılımının Tanılayıcı Kullanımı ve Advers Perinatal Sonuçlar ile Doğum Zamanı için Protein-kreatinin Oranı
    (2021) Gölbaşı, Hakan; Ömeroğlu, İbrahim; Dereli Akdeniz, Didem; Ekin, Atalay; Gölbaşı, Ceren
    Amaç: Çal›flmam›zda, proteinürisi olan veya olmayan hipertansif gebelerde perinatal ve neonatal sonuçlar› de¤erlendirmeyi amaçla- d›k. Spot üriner protein ile kreatinin oran›n›n (P/C) ve 24-saatlik protein at›l›m›n›n sonuçlar üzerindeki prediktivitesini karfl›laflt›r- d›k. Yöntem: Gebeli¤in 20. ve 37. haftalar› aras›nda yeni hipertansiyon tan›s› alm›fl 230 gebe retrospektif olarak çal›flmaya dahil edildi. Al›- nan 24 saatlik idrar ve P/C ile belirlenen protein seviyesine göre hastalar iki gruba ayr›ld›. Proteinüri varl›¤› ve seviyesi, P/C oran›y- la olan iliflkisi ve bu bulgular ile perinatal sonuçlar aras›ndaki iliflki de¤erlendirildi. Bulgular: Do¤um esnas›ndaki gestasyonel yafl ve gecikme dönemi (hipertansiyon tan›s› ile do¤um aras›ndaki süre), ?300 mg/24 saat ve P/C ?0.3 de¤erlerine sahip gebelerde anlaml› flekilde daha er- kendi. Advers neonatal sonuçlar, proteinürisi ?300 mg/24 saat ve P/C?0.3 olan hastalarda anlaml›yd›. 24 saatlik idrarda üriner pro- tein seviyeleri, P/C ?0.3 de¤erine sahip gebelerde anlaml› flekilde daha yüksekti ve 24 saatlik proteinüri ile P/C aras›nda anlaml› fle- kilde pozitif bir korelasyon bulundu (r=0.382, p<0.001). Sonuç: Çal›flmam›z, hipertansif gebelerde 24 saatte ?300 mg’lik bir protein kayb› ve spot idrarda ?0.3’lük bir P/C oran›n›n advers perinatal sonuçlarla iliflkili oldu¤unu ortaya koymufltur. Ayr›ca, hi- pertansif gebelerde ?300 mg/gün seviyesinde proteinürinin ve ?0.3’lük spot idrar P/C oran›n›n bu gebeleri erken do¤um riskine e¤ilimli k›ld›¤›n› tespit ettik.
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    Intra- and Interobserver Reproducibility of Placental Shear Wave Elastography Measurements
    (Wiley, 2025) Cakir, Zubeyde Emiralioglu; Can, Sevim Tuncer; Golbasi, Hakan; Bayraktar, Burak; Gercik, Ilayda; Aktas, Hale Ankara; Ekin, Atalay
    Objectives To evaluate the intra- and interobserver reproducibility of placental shear wave elastography (SWE) in healthy third-trimester singleton pregnancies.Methods This prospective study included 80 women with singleton pregnancies between 28 and 37 weeks of gestation. Placental stiffness was measured using point SWE at central and peripheral regions. Each participant was evaluated twice by 1 observer and once by another. Intraclass correlation coefficients (ICCs) were calculated to assess reproducibility.Results Placental SWE showed moderate reproducibility. In anterior placentas, intraobserver ICCs were 0.681 for peripheral and 0.715 for central regions, while interobserver ICCs were 0.630 and 0.701, respectively. In posterior placentas, intraobserver ICCs were 0.785 for peripheral and 0.765 for central regions, with interobserver ICCs of 0.717 and 0.753, respectively. In the total cohort, peripheral SWE velocity had an intraobserver ICC of 0.728 and interobserver ICC of 0.672, while central SWE velocity demonstrated comparable values, with intraobserver ICC of 0.729 and interobserver ICC of 0.727.Conclusion Placental SWE demonstrated moderate intra- and interobserver reproducibility, with minor variations depending on placental location. Despite these differences, measurement reliability was sufficiently acceptable to support its feasibility as a noninvasive adjunct in placental assessment.
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