Browsing by Author "Ozcelik, Sinem"
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Conference Object Comparative Analysis of Restless Legs Syndrome and Neuropathic Pain Impact on Walking and Balance in Multiple Sclerosis: Clinical and Radiographic Insights(Sage Publications Ltd, 2024) Ozdogar, Asiye Tuba; Kaya, Ergi; Ozcelik, Sinem; Unal, Gozde Deniz; Ozakbas, SerkanConference Object Enhancing Disability Progression Assessment in Multiple Sclerosis: Introducing the EDSS-Plus Score(Sage Publications Ltd, 2024) Ozcelik, Sinem; Ozdogar, Asiye Tuba; Alizada, Said; Cinar, Bilge Piri; Ozakbas, SerkanConference Object Evaluating the Effectiveness of No Evidence of Disease Activity-3 in Managing Progression Independent of Relapse Activity and Relapse-Associated Worsening in Multiple Sclerosis(Sage Publications Ltd, 2024) Ozcelik, Sinem; Ozdogar, Asiye Tuba; Alizada, Said; Ozakbas, Serkan[No Abstract Available]Conference Object Evaluating the Impact of MS Medications on Pregnancy Outcomes: A Retrospective Cohort Study(Sage Publications Ltd, 2024) Kaya, Ergi; Simsek, Yasemin; Ozcelik, Sinem; Caliskan, Can; Ozakbas, SerkanConference Object Exploring Familial Multiple Sclerosis: Insights From a Cohort Analysis(Sage Publications Ltd, 2024) Ozakbas, Serkan; Simsek, Yasemin; Caliskan, Can; Ozcelik, SinemConference Object Investigating the Impact of Pregnancy on Disease Course in Multiple Sclerosis: A Retrospective Analysis(Sage Publications Ltd, 2024) Simsek, Yasemin; Ozakbas, Serkan; Kaya, Ergi; Ozcelik, Sinem; Caliskan, CanConference Object Pregnancy in Multiple Sclerosis and Its Impact on Disease Course(Sage Publications Ltd, 2024) Aslan, Taha; Kaya, Ergi; Simsek, Yasemin; Ozcelik, Sinem; Ozdogar, Asiye Tuba; Ozakbas, SerkanConference Object RN-Nurse(Sage Publications Ltd, 2024) Simsek, Yasemin; Ozakbas, Serkan; Kaya, Ergi; Ozcelik, Sinem; Caliskan, CanArticle The Role of Pregnancy in Relapsing-Remitting Ms Prognosis: a Five-Year Study(Elsevier Sci Ltd, 2025) Kaya, Ergi; Aslan, Taha; Simsek, Yasemin; Ozcelik, Sinem; Ozakbas, SerkanIntroduction: Multiple sclerosis (MS) frequently affects women during their reproductive years, leading to growing interest in the interaction between pregnancy and MS progression. The relationship between pregnancy and MS prognosis has been widely studied, yet long-term outcomes remain controversial, with studies presenting conflicting results. Aim: This study aims to assess the long-term impact of pregnancy on MS prognosis by examining relapse rates, Expanded Disability Status Scale (EDSS) scores, and MRI activity over three and five years after delivery. Method: A total of 111 women with MS (wwMS) who delivered either preterm or at full term after MS diagnosis were retrospectively studied. The participants were grouped into those who experienced no relapses during pregnancy (NRG) and those who did (RG). A control group of 85 non-pregnant wwMS (NPG) with matched demographic and clinical characteristics was included for comparative analysis. Clinical data such as relapse rates, EDSS scores, and MRI findings were collected and analyzed statistically to determine the potential impact of pregnancy on MS. Result: Of the women who delivered post-MS diagnosis, 11 experienced relapses during pregnancy. There were no significant differences between the three groups regarding prepregnancy annualized relapse rate, EDSS scores, age at diagnosis, age at pregnancy, oligoclonal band positivity, first symptom localization, or disease-modifying therapy use (p > 0.05). Both the NRG and RG groups experienced significantly more relapses compared to the NPG group during the first three and five years post-delivery (p < 0.05). Additionally, the RG group had a higher relapse rate in the third year after delivery compared to the NRG group (p < 0.05). Conclusion: Having a delivery after an MS diagnosis is associated with increased relapse activity, particularly within the first three years postpartum. However, this heightened relapse activity does not appear to contribute to long-term disability accumulation and MRI activity in wwMS. These findings support the importance of individualized postpartum monitoring.Conference Object The Role of Pregnancy in Shaping Ms Prognosis: a Five-Year Study(Sage Publications Ltd, 2024) Ozcelik, Sinem; Kaya, Ergi; Simsek, Yasemin; Basaran, Tuncay; Aslan, Taha; Ozakbas, Serkan[No Abstract Available]Conference Object Which One Is More Progressive: Primary or Secondary Progressive Multiple Sclerosis(Sage Publications Ltd, 2024) Ozcelik, Sinem; Kaya, Ergi; Ozdogar, Asiye Tuba; Ozakbas, SerkanConference Object Which one is more progressive; Primary, or Secondary Progressive Multiple Sclerosis?(Sage Publications Ltd, 2024) Ozcelik, Sinem; Kaya, Ergi; Ozdogar, Asiye Tuba; Ozakbas, Serkan[No abstract available]
