Browsing by Author "Teichmann, Birgit"

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Citation - WoS: 1
Citation - Scopus: 1
Attitudes Toward Pre-Symptomatic Screening for Alzheimer's Dementia in Five European Countries: a Comparison of Family Members of People With Alzheimer's Dementia Versus Non-Family Members
(Frontiers Media Sa, 2023-12-15) Angelidou, Ioanna A.; Makri, Marina; Beyreuther, Konrad; Rovira, Merce Boada; Despoti, Akyllina; Engelborghs, Sebastiaan; Miguel, Andrea; Yener, Görsev; Yerlikaya, Deniz; Boada Rovira, Mercè; Teichmann, Birgit
Introduction: Pre-symptomatic screening is getting more attention in healthcare as it detects the risk for developing neurodegenerative diseases like Alzheimer's disease (AD), which is very useful for treatment or prevention. AD screening could play an important role in individuals with at least one affected first-degree relative, but also without family history. As the demand for screening is rising worldwide, it is important to consider possible cross-cultural differences in attitudes toward pre-symptomatic screening in order to tailor healthcare services to the needs of each country.Objective: This study aims to investigate the attitudes of family members and non-family members of people with dementia toward pre-symptomatic screening and explore possible differences in attitudes across five European countries (Belgium, Germany, Greece, Spain, Turkey) using translated versions of the Perceptions regarding pRE-symptomatic Alzheimer's Disease Screening questionnaire (PRE-ADS).Methods: The multicultural sample (N = 650) was recruited from samples that were previously used in validation studies of the translated PRE-ADS versions. The subscale Acceptability of Screening, consisting of five PRE-ADS items to specifically explore willingness to undergo screening, was created. Iota nternal consistency was measured, and structural validity was determined using Confirmatory Factor Analysis (CFA). Group comparisons were performed to investigate differences in attitudes toward pre-symptomatic AD screening regarding family history and country of origin using the PRE-ADS and the Acceptability of Screening mean scores.Results: Construct validity was acceptable for the PRE-ADS. Both the PRE-ADS (alpha = 0.76) and its subscale Acceptability of Screening (alpha = 0.90) had good internal consistency. Overall, 56.9% of the total sample expressed a positive intention toward pre-symptomatic AD screening. T-tests showed significantly higher mean scores of participants with an affected family member. An international comparison revealed differences in the Acceptability of Screening mean score across the five European countries. No cross-cultural differences were found for the PRE-ADS mean score after adjusting for confounding variables.Conclusion: The PRE-ADS and its subscale are reliable tools for assessing pre-symptomatic AD screening attitudes. Variations in the acceptability of screening seem to be linked to family history and cultural influences. Further research with larger samples is needed to explore underlying relationships.
Citation - WoS: 11
Citation - Scopus: 10
Cross-Cultural Comparison of Mmse and Rudas in German and Turkish Patients With Alzheimer's Disease
(Amer Psychological Assoc, 2022-03) Celik, Simge; Onur, Oezguer; Yener, Görsev; Kessler, Josef; Oezbek, Yagmur; Meyer, Patric; Froelich, Lutz; Özbek, Yagmur; Teichmann, Birgit
Objective: Given the increasing cultural, linguistic diversity in Europe, there is a growing need for cognitive screening tools that minimize the influence of linguistic, cultural, and demographic differences as they are the first means to determine the need for further clinical evaluation of individuals with suspected cognitive impairment. This cross-sectional study compared performance on the Mini-Mental State Examination (MMSE) and the Rowland Universal Dementia Assessment Scale (RUDAS) in Alzheimer's Disease (AD) patients in relation to cultural, demographic, and immigration-related factors (acculturation, bilingualism). Method: The study comprised Turkish immigrant (n = 21) and monolingual, nonimmigrant German (n = 20) and Turkish (n = 24) patients with AD. All participants were administered cognitive screening tools, measures of depression, and dementia severity. Results: The mean MMSE total score was significantly higher in German patients with AD compared to both patient groups, but did not differ between native-born Turkish and Turkish immigrant groups. After adjustment for years of education, differences in MMSE performance were no longer significant between groups. Furthermore, bilingualism was associated with better performance on the MMSE in Turkish-immigrant patients. The mean RUDAS total scores were similar between groups with and without adjustment for educational level. Performance on the RUDAS was not associated with demographic and immigration-related variables. Conclusions: The findings highlight the need to consider the educational background, linguistic integration of older non-Western immigrants for the objective characterization of cognitive profiles. The results provide support for the use of the RUDAS, particularly, among older Turkish immigrants with lower educational levels and varying degrees of acculturation, bilingualism.