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Picture
Cihangir_Yandim.jpg picture
Full Name
Yandım, Cihangir
Variants
Yandim, Cihangir
Yandim, C.
Yandim, Ci̇hangi̇r
Yandım, C.
Yandım, Ci̇hangi̇r
 
Main Affiliation
05.08. Genetics and Bioengineering
 
Email
cihangir.yandim@ieu.edu.tr
 
Link to YOK Profile
YÖK Profile
ORCID
0000-0002-2050-6186
Link to Google Profile
Google Scholar Profile
Scopus Author ID
36474168400
Researcher ID
AAA-2250-2021
 
Biography
Dr. Yandım, İzmir Özel Çakabey Lisesi'ndeki eğitimini takiben lisansını Moleküler Biyoloji ve Genetik alanında Bilkent Üniversitesi’nde tamamlamıştır. ABD’de Harvard Üniversitesi Tıp Fakültesi ve de Teksas Üniversitesi Southwestern Tıp Fakültesi'nde immünoloji ve kök hücre tedavisi alanlarında çalışmalarda bulunmuştur. Gen kontrolü ve epigenetik konularına olan bilimsel ilgisi kendisini bu alanlarda Londra İmparatorluk Üniversitesi'nde (Imperial College London) doktora yapmaya yönlendirmiştir. Doktora süresince Birleşik Krallık Tıbbi Araştırmalar Konseyi Bursu ile desteklenmiştir. Henüz tedavisi mümkün olmayan, nörolojik bir hastalık olan atakside gen ifadesi bozukluğunu gidermeye yönelik buluşları kendisini klinik denemelere yönlendirmiştir. Bu alandaki çalışmasını dünyadaki en yüksek tirajli bilim dergilerinden biri olan "The Lancet"te yayınlamıştır. Doktora üstü çalışmalarına yine Londra’da, bu kez Kanser Araştırma Enstütüsü (The Institute of Cancer Research)’nde devam etmiş ve burada kanserde sinyal iletimi çalışmıştır. Şu anda tekrarlı DNA dizilerinin kanser ve yaşlanmayla ilişkisi üzerine olan çalışmalarına ağırlık vermektedir. Ayrıca, interdisipliner biyoloji ve yeni nesil hesaplamalı ilaç dizaynıyla ilgili çalışmalar gerçekleştirmektedir. Dr. Yandım ayrıca İzmir Biyotıp ve Genom Merkezi (iBG)’nde fahri bilimsel araştırmacı statüsündedir.
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Following his education at Izmir Private Çakabey Highschool, Dr. Yandım obtained his BSc. in Molecular Biology and Genetics from Bilkent University. He conducted research at Harvard University Medical School as well as University of Texas Southwestern Medical Center, where he performed research on immunology and stem cell treatment. His emerging interest in gene control and epigenetics paved the way for him to do a PhD in this field at Imperial College London, where he was supported by a full scholarship from the Medical Research Council of United Kingdom. His findings on reversing gene dysregulation in an incurable form of ataxia led him to pursue an exploratory clinical trial. He published the results of this study in "The Lancet", which is one of the top-ranked scientific journals in the world. He continued his postdoctoral studies also in London at the Institute of Cancer Research, where he studied signal transduction in cancer. He is currently focused on revealing the interplay between repetitive DNA and cancer as well as aging. He also conducts studies on interdisciplinary biology and next-generation computational drug design.
Dr. Yandım is an honorary associate at Izmir Biomedicine and Genome Center (iBG).
Country
Turkey
Status
Current Staff
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Publications
(Articles)

Author

  • 1 Bursalı, Ahmet
  • 1 Dağlar, G.
  • 1 Günal, Tuğce
  • 1 Kaleli, Nurettin Mete
  • 1 Karagonlar, Z.F.
  • 1 Karakulah, Gökhan
  • 1 Karakuzulu, Basak Buse
  • 1 Karpat, Özüm
  • 1 Kaya, Ezgi
  • 1 Keske, Nazligul
  • . < previous next >

Subject

  • 4 Heterochromatin
  • 4 Repetitive Dna
  • 3 Cells
  • 3 Package
  • 3 Repetitive DNA
  • 3 Rna
  • 3 Transposable Elements
  • 2 Activation
  • 2 Bioinformatics
  • 2 Breast
  • . next >

Date issued

  • 10 2020 - 2025
  • 3 2010 - 2019

Type

  • 13 Article

Fulltext

  • 11 With Fulltext
  • 2 No Fulltext


Results 1-13 of 13 (Search time: 0.011 seconds).

Issue DateTitleAuthor(s)
12023Characterization of Cisplatin Loaded Hydrophilic Glycol Chitosan Modified Eumelanin Nanoparticles for Potential Controlled-Release ApplicationAtik, Aleyna; Günal, Tuğce; Acar Bozkurt, Pınar; Kose, Sila Naz ; Alp, Burcak ; Yandım, Cihangir ; Kaleli, Nurettin Mete
22022Comparative Molecular Dynamics Analyses on Pik3ca Hotspot Mutations With Pi3k Alpha Specific Inhibitors and AtpMentes, Muratcan; Karakuzulu, Basak Buse; Ucar, Gonlum Bahar; Yandim, Cihangir 
32019Dysregulated Expression of Repetitive Dna in Er+/Her2-breast CancerYandim, Cihangir ; Karakulah, Gokhan
42019Expression Dynamics of Repetitive Dna in Early Human Embryonic DevelopmentYandim, Cihangir ; Karakulah, Gokhan
52024Expressions of the Satellite Repeat Hsat5 and Transposable Elements Are Implicated in Disease Progression and Survival in GliomaKöse, Sıla Naz ; Yaraş, Tutku; Bursalı, Ahmet; Oktay, Yavuz; Yandım, Cihangir ; Karakulah, Gökhan
62021Identification of Differentially Expressed Genomic Repeats in Primary Hepatocellular Carcinoma and Their Potential Links To Biological Processes and SurvivalKarakulah, Gokhan; Yandim, Cihangir 
72023Identification of Ppa1 Inhibitor Candidates for Potential Repurposing in Cancer MedicineMenteş, Muratcan; Yandım, Cihangir 
82022In Silico Drug Screen Reveals Potential Competitive Mthfr Inhibitors for Clinical RepurposingKeske, Nazligul; Ozay, Basak; Tukel, Ezgi Yagmur; Mentes, Muratcan; Yandim, Cihangir 
92022Repeat Expression Is Linked To Patient Survival and Exhibits Single Nucleotide Variation in Pancreatic Cancer Revealing Ltr70:r.879a > GYandim, Cihangir ; Karakulah, Gokhan
102020Signature Changes in the Expressions of Protein-Coding Genes, Lncrnas, and Repeat Elements in Early and Late Cellular SenescenceKarakulah, Gokhan; Yandim, Cihangir 
112024Suppression of Ctc1 Inhibits Hepatocellular Carcinoma Cell Growth and Enhances Rhps4 CytotoxicityKıpçak, Arda; Sezan, Sıla; Karpat, Özüm; Kaya, Ezgi; Baylan, Sude; Sarıyar, Ece; Yandım, Cihangir 
122019Teffectr: an R Package for Studying the Potential Effects of Transposable Elements on Gene Expression With Linear Regression ModelKarakulah, Gokhan; Arslan, Nazmiye; Yandim, Cihangir ; Suner, Asli
132024Thyroid Hormone T3 Augments the Cytotoxicity of Sorafenib in Huh7 Hepatocellular Carcinoma Cells by Suppressing Akt ExpressionUyulgan, S.; Köse, S.N. ; Kıpçak, A.; Başkan, Y.; Dağlar, G.; Karagonlar, Z.F.; Yandım, C. 

 

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