Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14365/4022
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DC Field | Value | Language |
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dc.contributor.author | Oktay, Esin | - |
dc.contributor.author | Sahin, Mustafa | - |
dc.contributor.author | Erdogan, Atike Pinar | - |
dc.contributor.author | Ozveren, Ahmet | - |
dc.contributor.author | Yilmaz, Senem | - |
dc.contributor.author | Ekinci, Ferhat | - |
dc.contributor.author | Demir, Bilgin | - |
dc.date.accessioned | 2023-06-16T15:06:39Z | - |
dc.date.available | 2023-06-16T15:06:39Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 2602-3164 | - |
dc.identifier.uri | https://doi.org/10.14744/ejmi.2021.09037 | - |
dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/506000 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14365/4022 | - |
dc.description.abstract | Objectives: To search the prognostic value of an inflammation based prognostic score in older patients with hormone positive, Her2 negative metastatic breast cancer. Methods: A retrospective study of 82 female patients aged 65 years and older with hormon receptor positive, Her-2 negative metastatic breast cancer diagnosed between 2011 and 2018 was conducted with collection of clinical and laboratory data. The inflammatory prognostic index (IPI) was calculated as C-reactive protein × NLR (neutrophil/ lym- phocyte ratio)/serum albumin. Survival estimates were calculated with Kaplan-Meier method. Results: The optimal cut-off points of IPI for the stratification of OS was found to be 0,75. Based on this cutoff value, patients were categorized as IPI-high and IPI-low group. High IPI was significantly associated with advanced stage at diagnosis. (p=0.03) The mean OS was 64 months in the IPI-high group and 66.9 months in the IPI-low group. (p=0,813) In patients receiving hormonotherapy in first line treatment PFS was 34.6 months in the IPI-low group and 14.5 months in the IPI high group, and a statistically significant difference was found compared to patients who received chemo- therapy in the first line. (p=0,042). Conclusion: Measurement of systemic inflammatory response in older adults with metastatic breast cancer is reliable, available, and can be clinically incorporated into current geriatric oncology algorithms | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Eurasian Journal of Medical Investigation | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | The Value of Inflammatory Prognostic Index in Older Patients with Hormone Receptor Positive Metastatic Breast Cancer | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.14744/ejmi.2021.09037 | - |
dc.department | İzmir Ekonomi Üniversitesi | en_US |
dc.identifier.volume | 5 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 515 | en_US |
dc.identifier.endpage | 520 | en_US |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.trdizinid | 506000 | en_US |
dc.identifier.scopusquality | N/A | - |
dc.identifier.wosquality | N/A | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Article | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
Appears in Collections: | TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection |
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