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https://hdl.handle.net/20.500.14365/4093
Title: | Is There a Correlation Between Left Atrium Diameter and Nt-Probnp Levels in Resistant Hypertension? |
Authors: | Şekercioğlu, Eser Türkoğlu, Ebru İpek |
Abstract: | Objectives: Resistant hypertension (RHT) definesuncontrolled blood pressure despite appropriate treatmentand identifies a high-risk population, which may benefitfrom different diagnostic and therapeutic approaches. Thisstudy has investigated the relationship between left atrialdiameter (LAD) and N-terminal por-brain type natriureticpeptide (NT-proBNP) levels in true RHT patients withsinus rhythm.Materials and Methods: The outpatient data ofKemalpaşa State Hospital’s cardiology clinic has beenreviewed retrospectively. The patients with RHT areincluded but patients with secondary hypertension, pseudoRHT, atrial fibrillation and left ventricle ejection fraction<50% are excluded from analysis. Age and gender specificcut-off levels have been used for NT-proBNP.Results: Among 74 true RHT patients, 48 were female.The mean age was 61.9±11.2 years. Mean LAD was40.9±4.0 mm and mean NT-proBNP was 330.3±394.9 pg/mL. Larger LAD was correlated to higher levels of NTproBNP (r=0.451, p<0.001). Even after controlling for age,gender, heart rate, systolic and diastolic blood pressures,partial correlation was continued between LAD and NTproBNP (r=0.234, d.f=67, p<0,05).Conclusion: The current study showed that larger LADis related to higher levels of NT-proBNP in RHT, whichmay allow us to use simple echocardiographic parameterto diagnose high-risk patients and hypervolemia instead ofNT-proBNP, an expensive biomarker. Because of singlecenter results and limited number of patients, further studiesare needed. |
URI: | https://doi.org/10.32596/ejcm.galenos.2019.00009 https://search.trdizin.gov.tr/yayin/detay/325678 https://hdl.handle.net/20.500.14365/4093 |
ISSN: | 2147-1924 |
Appears in Collections: | TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection |
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