Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14365/5161
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dc.contributor.authorGüllüoğlu, Halil-
dc.contributor.authorHünerli, Duygu-
dc.contributor.authorÇakmur, Raif-
dc.contributor.authorDönmez Çolakoğlu, Berril-
dc.contributor.authorAda, Emel-
dc.contributor.authorYener, Gorsev-
dc.date.accessioned2024-02-24T13:39:00Z-
dc.date.available2024-02-24T13:39:00Z-
dc.date.issued2024-
dc.identifier.issn1010-660X-
dc.identifier.issn1648-9144-
dc.identifier.urihttps://doi.org/10.3390/medicina60010033-
dc.identifier.urihttps://hdl.handle.net/20.500.14365/5161-
dc.description.abstractBackground and Objectives: The pathophysiology of mild cognitive impairment in Parkinson's disease (PD-MCI) is still not fully elucidated. It has been shown in a few studies in the literature that volume loss in the occipital, parietal and frontal cortices and atrophy in the hippocampus of PD-MCI patients can occur in the early stages of PD. The aim of this study was to evaluate the relationship between gray and white matter volumes and different neuropsychological tests and volumetric magnetic resonance imaging parameters in patients with mild cognitive impairment in Parkinson's disease (PD-MCI). Materials and Methods: Twenty-six PD-MCI and twenty-six healthy elderly (HC) were included in this study. Results: We found that Mini Mental State Examination, Trail Making Test Part A, Clock Drawing Test, Benton Line Judgment Orientation Test and pentagon figure-copying scores were impaired in PD-MCI patients due to the decrease in brain volumes. Conclusions: Our study revealed that among PD-MCI patients, there was a more noticeable decline in White matter volume (WMV) based on volumetric Magnetic Resonance Imaging (MRI) compared to the localized loss of GMV. We think that these abnormal neuropsychological tests in PD-MCI patients can be used as pretests in the evaluation of the stage of transition to dementia.en_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMedicina-Lithuaniaen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcognitive impairmenten_US
dc.subjectParkinson's diseaseen_US
dc.subjectdementiaen_US
dc.subjectneuropsychology testingen_US
dc.subjectDiagnostic-Criteriaen_US
dc.subjectDementiaen_US
dc.subjectMatteren_US
dc.subjectAtrophyen_US
dc.subjectHippocampalen_US
dc.subjectPutamenen_US
dc.subjectScaleen_US
dc.subjectStateen_US
dc.titleStructural and Functional Changes in Mild Cognitive Impairment in Parkinson's Diseaseen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/medicina60010033-
dc.identifier.pmid38256295en_US
dc.identifier.scopus2-s2.0-85183173002en_US
dc.departmentİzmir Ekonomi Üniversitesien_US
dc.authorscopusid18233644400-
dc.authorscopusid57209025312-
dc.authorscopusid6701745542-
dc.authorscopusid36659088100-
dc.authorscopusid6603810790-
dc.authorscopusid7003804891-
dc.identifier.volume60en_US
dc.identifier.issue1en_US
dc.identifier.wosWOS:001151458700001en_US
dc.institutionauthor-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ1-
dc.identifier.wosqualityQ3-
item.grantfulltextopen-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
crisitem.author.dept09.02. Internal Sciences-
crisitem.author.dept09.03. Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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