Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14365/5425
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dc.contributor.authorGülhan, İbrahim-
dc.contributor.authorÖzdemir, Raziye-
dc.contributor.authorİleri, Alper-
dc.contributor.authorİleri, Hande-
dc.contributor.authorÖzcan, Sena-
dc.contributor.authorÖztürk, Ayse Betü-
dc.contributor.authorGökçü, Mehmet-
dc.date.accessioned2024-08-25T15:13:03Z-
dc.date.available2024-08-25T15:13:03Z-
dc.date.issued2024-
dc.identifier.issn0256-4947-
dc.identifier.issn1319-9226-
dc.identifier.urihttps://doi.org/10.5144/0256-4947.2024.220-
dc.identifier.urihttps://hdl.handle.net/20.500.14365/5425-
dc.description.abstractBACKGROUND: The role of endocervical curettage (ECC) in the diagnosis of cervical intraepithelial neoplasia (CIN) is a controversial topic. OBJECTIVES: Investigate the role of ECC in the diagnosis of CIN in human papillomavirus (HPV) positive patients. DESIGN: Retrospective SETTING: A tertiary training and research hospital PATIENTS AND METHODS: This study included patients who were referred for colposcopy between 2018-2022 because of abnormal screening results. ECC results, age, cytology, HPV status, and colposcopic impression of the patients were extracted from the medical records. Multinomial logistic regression analyses were performed to identify factors that could predict CIN on ECC. MAIN OUTCOME AND MEASURES: The likelihood of high-grade squamous intraepithelial lesions (HSIL) in ECC in patients with cervical biopsy results of normal and low-grade squamous intraepithelial lesion (LSIL). SAMPLE SIZE: 2895 women RESULTS: In patients with normal and LSIL cervical biopsy results, HSILs were detected in 6.7% of ECC results. There was no difference in the detection rates of CIN in ECC among groups with smear results negative for intraepithelial lesions or malignancy (NILM), atypical squamous cells of undetermined significance (ASC-US), and LSIL. The likelihood of HSIL being observed in ECC was 2.2 times higher in patients with HPV16. The probability of LSIL disanois was 2.3 times higher in women aged 50-59 years and 2.8 times higher in women >= 60 years compared to the reference group of <30 years. The probability of LSIL was 2.3 and HSIL by ECC was 2.2 times higher in both age categories (P<.012 P <.012 and P =.032, respectively) than the reference group of <30 years. CONCLUSION: Regardless of colposcopic findings, ECC should be performed in patients with smear results of NILM who are positive for HPV16, in patients with smear results of ASC-US and LSIL who are positive for any oncogenic type of HPV and in patients 50 and above with any result of smear or any oncogenic HPV type. LIMITATIONS: We did not have the components of the HPV types in mixed groups.en_US
dc.language.isoenen_US
dc.publisherK faisal spec hosp res centreen_US
dc.relation.ispartofAnnals of Saudi Medicineen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCancer Screening-Testsen_US
dc.subjectConsensus Recommendationsen_US
dc.subjectColposcopyen_US
dc.subjectManagementen_US
dc.subjectWomenen_US
dc.subjectGuidelinesen_US
dc.subjectBiopsyen_US
dc.titleThe role of endocervical curettage in the diagnosis of cervical intraepithelial neoplasia in human papillomavirus positive patientsen_US
dc.typeArticleen_US
dc.identifier.doi10.5144/0256-4947.2024.220-
dc.identifier.pmid39127897en_US
dc.identifier.scopus2-s2.0-85201064161en_US
dc.departmentİzmir Ekonomi Üniversitesien_US
dc.authorscopusid14047025900-
dc.authorscopusid46761319200-
dc.authorscopusid56003553300-
dc.authorscopusid57387774200-
dc.authorscopusid59257404000-
dc.authorscopusid59257387700-
dc.authorscopusid6504303111-
dc.identifier.volume44en_US
dc.identifier.issue4en_US
dc.identifier.startpage220en_US
dc.identifier.endpage227en_US
dc.identifier.wosWOS:001289518500002en_US
dc.institutionauthor-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ2-
dc.identifier.wosqualityQ3-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.languageiso639-1en-
crisitem.author.dept09.04. Surgical Sciences-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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