Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14365/5431
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Okan, Taha | - |
dc.contributor.author | Doruk, Mehmet | - |
dc.contributor.author | Öztürk, Ali | - |
dc.contributor.author | Topaloğlu, Caner | - |
dc.contributor.author | Doğduş, Mustafa | - |
dc.contributor.author | Yılmaz, Mehmet Birhan | - |
dc.date.accessioned | 2024-08-25T15:13:06Z | - |
dc.date.available | 2024-08-25T15:13:06Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 2075-4418 | - |
dc.identifier.uri | https://doi.org/10.3390/diagnostics14141495 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14365/5431 | - |
dc.description.abstract | (1) Background: Dyslipidaemia and insulin resistance are major risk factors for coronary artery disease (CAD). This study investigated the relationship between plasma atherogenic index (PA-I), triglyceride-glucose index (TGI) and other lipid ratios with the presence and prediction of CAD among different age categories. (2) Methods: The study included 223 participants diagnosed with CAD and those with normal coronary arteries (normal group) by coronary computed tomography angiography (CCTA). Participants were categorised by age and sex: premature CAD (PCAD) for men under 55 and women under 65, and older groups as elderly. (3) Results: PA-I, Lipid Combined Index, Castelli Risk Indices, and TGI were significantly higher in the PCAD group compared to the control group (p < 0.05). ROC analysis showed that a PA-I cut-off of 0.41 had a sensitivity of 62% and a specificity of 58% for predicting PCAD, while a TGI cut-off of 8.74 had a sensitivity of 68% and a specificity of 62%. In the elderly, no significant differences in these indices were found between the CAD and normal groups. (4) Conclusions: Traditional lipid profiles and non-traditional lipid indices such as PA-I and TGI show significant differences in predicting CAD in younger populations but not in older groups. TGI and PA-I may be promising biomarkers for the prediction of PAD, although further validation is needed. | en_US |
dc.language.iso | en | en_US |
dc.publisher | MDPI | en_US |
dc.relation.ispartof | Diagnostics | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | premature coronary artery disease | en_US |
dc.subject | plasma atherogenic index | en_US |
dc.subject | triglyceride-glucose index | en_US |
dc.subject | lipoproteins ratios | en_US |
dc.subject | coronary computed tomography angiography | en_US |
dc.subject | Density-Lipoprotein Cholesterol | en_US |
dc.subject | Cardiovascular Risk | en_US |
dc.subject | Insulin-Resistance | en_US |
dc.subject | Heart-Disease | en_US |
dc.subject | Tg/Hdl-C | en_US |
dc.subject | Inflammation | en_US |
dc.subject | Association | en_US |
dc.subject | Parameters | en_US |
dc.title | Evaluation of Plasma Atherogenic Index, Triglyceride-Glucose Index and Other Lipid Ratios as Predictive Biomarkers of Coronary Artery Disease in Different Age Groups | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.3390/diagnostics14141495 | - |
dc.identifier.pmid | 39061632 | en_US |
dc.identifier.scopus | 2-s2.0-85199587632 | en_US |
dc.department | İzmir Ekonomi Üniversitesi | en_US |
dc.authorscopusid | 6506596632 | - |
dc.authorscopusid | 59235319300 | - |
dc.authorscopusid | 59235133800 | - |
dc.authorscopusid | 6506971703 | - |
dc.authorscopusid | 57204894031 | - |
dc.authorscopusid | 7202595585 | - |
dc.identifier.volume | 14 | en_US |
dc.identifier.issue | 14 | en_US |
dc.identifier.wos | WOS:001278144500001 | en_US |
dc.institutionauthor | … | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
item.openairetype | Article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | 09.02. Internal Sciences | - |
crisitem.author.dept | 09.02. Internal Sciences | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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