01. Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
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Browsing 01. Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed by Author "Abasıyanık, Z."
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Article Citation - WoS: 3Citation - Scopus: 3Discriminative Ability of the Original and Short Form of the Activities-Specific Balance Confidence Scale and Its Individual Items for Falls in People With Multiple Sclerosis(Springer Science and Business Media Deutschland GmbH, 2024) Abasıyanık, Z.; Kahraman, T.; Baba, C.; Sağıcı, Ö.; Ertekin, Ö.; Özakbaş, SerkanBackground: Balance confidence is an essential component of fall risk assessment in persons with multiple sclerosis (pwMS). Aims: The aims of this cross-sectional study were to 1) investigate the ability of the 16-item Activities-specific Balance Confidence scale (ABC-16), 6-item Activities-specific Balance Confidence scale (ABC-6), and each item of the ABC-16 for distinguishing fallers and 2) determine cutoff scores for these scales to discriminate fallers and non-fallers in pwMS. Methods: One hundred and fifty-six participants [fallers/non-fallers: 60 (38.5%)/96 (61.5%), median EDSS: 1.5] were enrolled. Balance confidence was assessed using the ABC-16 and ABC-6. The self-reported number of falls in the past three months was recorded. Descriptive assessments, including walking, balance, and cognition were performed. Logistic regression and receiver operating characteristic analyses were conducted to estimate the sensitivities and specificities of the ABC-16 and ABC-6. Results: Both the ABC-16 (AUC: 0.85) and ABC-6 (AUC: 0.84) had the discriminative ability for falls. Each item of the ABC-16 scale was a significantly related to falls [odds ratio (OR) range: 1.38 to 1.89]. Items 8 and 10 had the highest odds ratio (OR: 1.85; 95%CI: 1.47–2.33, OR: 1.89; 95%CI: 1.49–2.40; respectively). We found cutoff scores of ≤ 70 of 100 (sensitivity: 71.67, specificity: 86.46) and ≤ 65/100 (sensitivity: 76.67, specificity: 79.17) in discrimination between fallers and non-fallers for the ABC-16 and ABC-6, respectively. Conclusion: Both original and short forms of the ABC scale are an efficient tool for discriminating fallers and non-fallers in pwMS. Although all items are related to falls, outdoor walking activities have the strongest associations with falls than other items. © The Author(s) 2024.Article Citation - WoS: 6Citation - Scopus: 8Manifestations of Walking Fatigability in People With Multiple Sclerosis Based on Gait Quality and Distance Walked During the Six Minutes Walking Test(Elsevier B.V., 2024) Santinelli, F.B.; Abasıyanık, Z.; Ramari, C.; Gysemberg, G.; Kos, D.; Pau, M.; Kalron, A.; Özakbaş, SerkanBackground: Distance walking fatigability (DWF) in people with multiple sclerosis (pwMS) is defined as a decrease in the distance walking over time. However, declines in gait quality (i.e., gait quality fatigability- GQF) may occur independently or alongside DWF. Objective: i) to investigate how walking fatigability manifests and its prevalence in pwMS; ii) to describe the temporal pattern of the changes of specific gait characteristics during the 6-minute walking test (6MWT) Methods: Eighty-eight pwMS (EDSS 4[0–6.5], 49[21–70] years) and 47 healthy controls (HC- 46[25–60] years) performed the 6MWT wearing inertial measurement units. Gait characteristics (stride length, sensor-based gait speed, cadence, double support, step duration, stance phase, step duration asymmetry, step duration variability, foot-strike, toe-off, and leg circumduction) and walking distance were recorded in 1-minute intervals. A fatigability index was calculated by comparing the last and first minute of the 6MWT to identify abnormal worsening based on cutoff scores. The manifestation of walking fatigability was counted. The temporal pattern of worsening of gait characteristics during the 6MWT was examined in pwMS exceeding the cutoff values, compared to pwMS without abnormal changes and HC, using a two-way ANOVA (group vs. minutes) Results: Thirty-five pwMS presented both DWF and GQF, 2 presented isolated DWF, 27 presented isolated GQF, and 24 presented non-walking fatigability. PwMS having GQF presented worsening in gait characteristics (cadence, step duration, step duration variability, or toe-off angle) from minute 2 onwards of the 6MWT, while HCs and pwMS without abnormal changes stabilized gait from minute 2 towards the end of the 6MWT. Conclusion: Walking fatigability in pwMS manifests not only as a decrease in walking distance but also as changes in gait quality. Understanding changes in gait characteristics during walking can help tailor rehabilitation interventions. © 2024 Elsevier B.V.Article Citation - Scopus: 1Prevalence and Magnitude of Perceived Dual-Task Difficulties in People with Multiple Sclerosis: An International Study(W.B. Saunders, 2025) Abasıyanık, Z.; Pedullà, L.; Kahraman, T.; Soler, B.; Santoyo-Medina, C.; Tacchino, A.; D'Hooge, M.Objective: To investigate the prevalence and magnitude of dual-task (DT) difficulties and the discriminative ability of 3 questionnaires evaluating perceived DT difficulties: the Dual-Tasking Questionnaire (DTQ), Dual-Task Screening List (DTSL), and Dual-task Impact on Daily life Activities Questionnaire (DIDA-Q). Design: Multicenter, cross-sectional study. Setting: Persons with multiple sclerosis (pwMS) and those without multiple sclerosis were recruited from 7 centers across 6 countries. Participants: A total of 540 participants (N=540): 175 with mild disability (mean Expanded Disability Status Scale, 2.1; mean age, 42.9), 181 with moderate-to-severe disability (mean Expanded Disability Status Scale, 5.3; mean age, 51.9), and 184 of those without multiple sclerosis (mean age, 44.8). Interventions: Not applicable. Main Outcome Measures: The cutoff scores of the DTQ, DTSL, and DIDA-Q and prevalence of DT difficulties were calculated. The effect size (ES) was calculated to determine the magnitude of the differences between groups (pwMS vs those without multiple sclerosis). The discriminative properties were identified by the area under the receiver operating characteristic curve (AUC). Cutoff values were estimated as the mean survey score plus 2 SDs of those without multiple sclerosis. Results: Prevalence ranged from 49%-87% in the moderate-to-severe disability and 25%-45% in the mild disability group. The cutoff scores were 45 of 100 for DTQ, 25 of 100 for DTSL, and 14 of 76 for DIDA-Q. The DTQ (ES, 0.61), DTSL (ES, 0.73), and DIDA-Q (ES, 0.80) demonstrated discriminative ability with a moderate-to-large ES, showing greater perceived DT difficulties in pwMS compared with those without multiple sclerosis. The DIDA-Q had the largest AUC (0.904) compared with DTSL (0.866), and DTQ (0.802). Conclusions: The DT difficulties were already perceived in almost half of the mildly disabled patients and increased with disability severity. The DTQ, DTSL, and DIDA-Q show discriminative ability, with the highest AUC and ES observed in DIDA-Q. The DTQ, DTSL, and DIDA-Q can clearly be used in pwMS for clinical and research purposes. © 2025 Elsevier B.V., All rights reserved.Article Citation - Scopus: 1Sedentary Behaviour and Related Factors in People With Multiple Sclerosis(Elsevier B.V., 2024) Ertekin, Ö.; Kara, T.; Abasıyanık, Z.; Kahraman, T.; Özakbaş, SerkanBackground: Sedentary behaviour is a major problem in persons with multiple sclerosis (pwMS). However, little is known about the related factors of sedentary behaviour in MS. Our study aimed to examine the association between sedentary behaviour and physical activity level, fear of falling, and fatigue. Method: Demographic and clinical data have been recorded. Sedentary behaviour was assessed with the Marshall Sitting Questionnaire, physical activity level was evaluated with the Godin Leisure Time Exercise Questionnaire, fear of falling was evaluated with the Fall Efficacy Scale International, and fatigue was evaluated with the modified fatigue impact scale (MFIS). The Timed 25-Foot Walk, 6-Minute Walk Test, Timed Up and Go Test, and 12-Item Multiple Sclerosis Walking Scale were also used to assess walking and perceived walking disability. Results: We recruited 71 pwMS [49 were female (69 %), mean age:38.08 years, median EDSS:1.5]. The mean daily sitting time was 593.54 min (∼10 h). No significant correlation was found between sitting times and demographics, leisure time physical activity, fear of falling, walking, perceived walking disability, and neurological disability level (p > 0.05). Logistic regression analysis indicated that being male increased the risk of sedentary behaviour by 3.08 times, being employed increased the risk of sitting by 4.65 times, and each point increase in MFIS scores resulted in a 1.03-fold elevation in the odds of prolonged sitting. Conclusion: The fact that pwMS, even with a mild disability spend almost 10 h sitting highlights the significance of sedentary behaviour in this population. Developing strategies to address modifiable factors, such as fatigue, may be effective in reducing sedentary behaviour. © 2023 Elsevier B.V.
