Browsing by Author "Feys, Peter"

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Different Gait Dynamics and Distance Walking/Gait Quality Fatigability Manifestation During the 6-Minute Walking in People With Multiple Sclerosis
(Sage Publications Ltd, 2024) Santinelli, Felipe Balistieri; Ramari, Cintia; Abasiyanik, Zuhal; Gysemberg, Griet; Kos, Daphne; Ozakbas, Serkan; Feys, Peter
Prevalence of Distance Walking Fatigability in Multiple Sclerosis According to MS Phenotype, Disability Severity and Walking Speed
(Elsevier France-Éditions Scientifiques Médicales Elsevier, 2025) Santinelli, Felipe Balistieri; Abasiyanik, Zuhal; Dalgas, Ulrik; Ozakbas, Serkan; Severijns, Deborah; Gebara, Benoit; Feys, Peter
Citation - WoS: 1
Citation - Scopus: 3
Reliability and Construct Validity of Three Self-Report Questionnaires Assessing Dual-Task Difficulties in People With Multiple Sclerosis: an International Study
(W B Saunders Co-elsevier inc, 2025) Abasiyanik, Zuhal; Pedulla, Ludovico; Kahraman, Turhan; D'Hooge, Mieke; Santoyo-Medina, Carme; Soler, Bernardita; Feys, Peter
Objective: To evaluate the reliability and validity of the dual-tasking questionnaire (DTQ), dual-task screening list (DTSL), and dual-task impact on daily life activities questionnaire (DIDA-Q). Design: Multicenter, cross-sectional study Setting: Persons with multiple sclerosis (pwMS) were recruited from 7 multiple sclerosis centers across 6 countries (Belgium, Chile, Italy, Israel, Spain, and Turkey). Participants: A total of 356 pwMS (mean age 47.5 +/- 11.5y, expanded disability status scale, 3.79 +/- 1.83) were enrolled. Interventions: Not applicable Main Outcome Measures: The reliability (internal consistency, test-retest, and measurement error) and construct validity (structural and convergent) were assessed. Results: The DTQ, DTSL, and DIDA-Q demonstrated excellent test-retest reliability (intraclass correlation coefficients [95% CI], 0.84 [0.80-0.87] to 0.90 [0.87-0.92]) and internal consistency (Cronbach a: 0.86-0.96). As hypothesized, the 3 questionnaires showed a strong correlation with each other, moderate-to-strong correlations with other self-report questionnaires (perceived walking difficulties, fatigue, and fear of falling), and low- to-moderate correlations with cognitive information processing speed, manual dexterity, and dual-task walking performance (walking with word list generation task), showing convergent validity. The DIDA-Q exhibited systematically superior properties. These results were also verified in subsets from 6 different countries. In the structural validity analysis, all questionnaires displayed 2 main factors, allocated as "motor-driven" and "cognitive-driven" subscales. Conclusions: The DTQ, DTSL, and DIDA-Q have good-to-excellent measurement properties, with the highest properties observed in DIDA-Q. The use of these self-reported questionnaires can be used in research and clinical practice to assess the effect of dual-task difficulties on the daily life of ambulatory pwMS. (c) 2024 by the American Congress of Rehabilitation Medicine.
Sustained Attention and Gait Pattern Changes During the 6-Minute Walk Test in Persons with Multiple Sclerosis
(Lippincott Williams & Wilkins, 2025) Abasiyanik, Zuhal; Kahraman, Turhan; Veldkamp, Renee; Ertekin, Ozge; Kalron, Alon; Ozakbas, Serkan; Feys, Peter
Background and purpose: It is unknown whether persons with multiple sclerosis (pwMS) can retain sustained attention and gait quality during long-distance walking tests. This study aimed to investigate changes in sustained attention and gait parameters during prolonged walking in pwMS with different levels of disability and healthy controls (HCs) and correlations of these changes with self-reported daily life difficulties. Methods: The 6-Minute Walk Test was performed with an auditory sustained attention task while wearing inertial measurement sensors. Participants were asked to respond verbally as quickly as possible to randomly presented auditory stimuli during 6 minutes of walking. The accuracy of answers, average reaction time, and gait parameters per minute were determined. Results: Thirty pwMS with mild disability (Expanded Disease Status Scale [EDSS] < 4.0), 16 pwMS with moderate-to-severe disability (EDSS 4.0 to 6.5), and 27 age-gender matched HCs were included. A significant group-by-time interaction effect as found for reactions times, which increased in mild and moderate-to-severe disability groups but not in HCs. Gait parameters deteriorated over time in all groups, but no significant group-by-time interaction was found. The decrease in sustained attention was not related to changes in gait or clinical outcomes, while deterioration in gait parameters was associated with perceived walking disability and dual-task difficulties in daily life. Discussion and Conclusions: Sustained attention during walking declined over time in pwMS, but not in HCs. However, gait parameters deteriorated in all groups. Worsening gait during simultaneous cognitive task execution may contribute to walking and dual-task difficulties in pwMS.