Browsing by Author "Kahraman, Turhan"
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Conference Object Age-Related Differences in E-Health Literacy in People with Multiple Sclerosis(Sage Publications Ltd, 2025) Yavas, Ipek; Karakas, Hilal; Celik, Rabia Gokcen Gozubatik; Cansiz, Melek; Ertekin, Ozge; Kahraman, TurhanConference Object Association Between Vascular Risk Factors and Cognitive Impairment in Multiple Sclerosis: a Cross-Sectional Study(Sage Publications Ltd, 2024) Ozakbas, Serkan; Aslan, Taha; Zengin, Ela; Kara, Irem; Simsek, Yasemin; Kahraman, TurhanArticle Citation - WoS: 3Citation - Scopus: 3Balance and Gait Impairment in Persons With Multiple Sclerosis With the Absence of Clinical Disability(Turkish Neurological Soc, 2020) Ayan, Hatice; Ertekin, Ozge; Kahraman, Turhan; Özakbaş, SerkanObjective: Impaired balance is one of the most important risk factors for falls in persons with multiple sclerosis (pwMS). The aim was to evaluate balance and gait performance in pwMS with the absence of clinical disability (pwMS-AD) compared with pwMS with minimal disability (MD) and healthy controls (HC). Materials and Methods: Nineteen pwMS-AD were assessed using the Expanded Disability Status scale (EDSS) score <= 1.5, 16 pwMS-MD (2.0 <= EDSS <= 3.0), and 39 HC were assessed using a posturography. Limits of stability (LOS), postural stability (PS) and fall risk index tests were performed. The Brief-Balance Evaluation Systems Test (Brief-BESTest), Activities-Specific Balance Confidence (ABC) scale, timed 25 foot walk test (T25FW) and 12-Item MS walking scale (MSWS-12) were used. Results: Significant differences were observed between pwMS-AD and pwMS-MD in terms of PS (overall, anteroposterior, mediolateral), Brief-BESTest, T25FW, and MSWS-12 (p<0.05). The stability limits (overall, forward LOS score) of the pwMS-AD group decreased significantly compared with the HC (p<0.05). There was also a significant difference in mediolateral PS, fall risk, Brief-BESTest and T25FW scores (p<0.05), but no significant difference was found in the ABC scale score (p=0.543) between pwMS-AD and HC. Conclusion: The results showed that pwMS with the absence of clinical disability had better balance and gait performance than pwMS with minimal disability, but compared with HC, pwMS-AD have impaired balance and gait performance; however, subjective confidence in balance is not significantly different. PwMSAD should be assessed regularly for the early detection of impaired balance and fall risk, even if there are no reported problems related to balance and gait.Conference Object Cognitive Difficulties, Coping Strategies and Barriers to Participation in Cognitive Rehabilitation in People With Multiple Sclerosis: A Qualitative Study Across Different Disability Levels(Sage Publications Ltd, 2025) Karakas, Hilal; Yavas, Ipek; Gokcen, Rabia; Celik, Gozubatik; Cansiz, Melek; Ertekin, Ozge; Kahraman, TurhanArticle Citation - WoS: 4Citation - Scopus: 4Dual-Task Difficulties as a Risk Factor for Unemployment in People With Multiple Sclerosis(Wiley, 2023) Kahraman, Turhan; Temiz, Hasretgül; Abasıyanık, Zuhal; Baba, Cavid; Özakbaş, SerkanBackground: No study has investigated the impact of dual-tasking difficulties as a risk factor for unemployment in people with multiple sclerosis (pwMS). The aim was to examine the influence of dual-task performance on employment status and work difficulties and to identify the predictors of employment status in pwMS.Methods: Eighty-four pwMS, including 42 employed and 42 unemployed, participated in the study. Dual-task difficulties were assessed using the Dual-task Impact on Daily-living Activities-Questionnaire (DIDA-Q), while dual-task performance was evaluated through the 30-second Walk Test and Nine-Hole Peg Test, incorporating a cognitive task. Walking and cognitive function were also measured.Results: Employed pwMS had better scores in walking, cognitive function, single and dual-task performance than unemployed pwMS (p < .05). Lower scores in walking (odds ratio [OR] = 1.81, p < .001) and upper extremity-related (OR = 1.44, p = .019) dual-task performance and higher scores in the cognitive subscale of the DIDA-Q questionnaire (OR = 1.20, p = .037) were significantly associated with higher odds of being unemployed. Among employed pwMS, DIDA-Q subscales showed moderate-to-strong correlations with MSWSDQ-23 scores. The other variables showed weak-to-moderate correlations with subscale and total scores of MSWSDQ-23.Conclusion: Cognitive function, as opposed to motor function, has been found to be a significant predictor of unemployment in pwMS.Conference Object Enhancing Fine Motor Assessment: The 9HPT-Extended as a Superior Alternative to the Standard 9HPT(Sage Publications Ltd, 2025) Unal, Gozde Deniz; Aydin, Esra; Caliskan, Can; Samadzade, Ulvi; Ozdogar, Asiye Tuba; Kahraman, Turhan; Ozakbas, SerkanConference Object Impact of Chronic Pain on Cognitive Reserve in Multiple Sclerosis(Sage Publications Ltd, 2025) Ozdogar, Asiye Tuba; Kahraman, Turhan; Alizada, Said; Ozakbas, SerkanConference Object Long-Term Effects of Ocrelizumab on Motor and Cognitive Functions in Progressive Multiple Sclerosis: A Three-Year Follow-Up Study(Sage Publications Ltd, 2025) Kaya, Ergi; Ozdogar, Asiye Tuba; Unal, Gozde Deniz; Kahraman, Turhan; Ozakbas, SerkanArticle Multipl Sklerozlu Bireylerde Üriner Semptomlar, Bağırsak Semptomları ve Cinsel İşlev Bozukluğunun Tedavisinde Pelvik Taban Kas Eğitimi: Geleneksel Derleme(2024) Kahraman, Turhan; Yavaş, İpek; Ertekin, ÖzgeMultipl skleroz (MS), santral sinir sisteminin otoimmün kaynaklı nöro dejeneratif bir hastalığıdır. MS’li bireyler santral sinir sistemi tutulumuna bağlı çok çeşitli semptomlar yaşayabilmektedir. MS’li bireylerin %80’inden fazlası üriner semptomlar, %39-73’ü bağırsak semptomları ve %40-90’ı cinsel işlev bo zukluğu bildirmektedir. Aynı zamanda bu semptomlar MS’li bireyin yaşam ka litesini olumsuz yönde etkileyen bir dizi soruna yol açmaktadır. Bu semptomların tedavisinde kullanılan fizyoterapi yöntemlerinden olan pelvik taban kas eğitimi günümüzde üriner inkontinans, pelvik organ prolapsusu ve fekal inkontinans için öncelikli tercih edilen bir tedavi seçeneğidir ayrıca cinsel işlevi iyileştirmede et kili olabileceğini gösteren çalışmalar bulunmaktadır. Bu derlemenin amacı, MS’li bireylerde pelvik taban kas eğitiminin önemini ve MS’ye bağlı üriner semptom lar, bağırsak semptomları ve cinsel işlev bozukluğunun yönetimindeki yerini vur gulamaktır. MS’li bireylerde pelvik taban kas eğitimi üriner inkontinans, aşırı aktif mesane ve cinsel işlev bozukluğu tedavisinde etkili bir yöntemdir. Ayrıca pelvik taban kas eğitimi alan MS’li bireylerde yaşam kalitesi de artmaktadır. Li teratürde biofeedback eğitiminin fekal inkontinans ve konstipasyon için etkili ol duğunu gösteren çalışmalar bulunmaktadır. Çalışmalar müdahalelerini pelvik taban kas eğitimi olarak tanımlanmasa da biofeedback eğitimi pelvik taban kas eğitiminde egzersizlerin doğrulanması ve eğitimin gerçekleşmesi amacıyla kul lanılan bir yöntemdir bu nedenle de pelvik taban kas eğitiminin fekal inkonti nansı ve konstipasyonu tedavi etmede etkili bir yöntem olduğu görülmektedir. MS’li bireylerde üriner retansiyonun tedavi edilmesinde mevcut bir çalışma bu lunmasa da ümit vaat eden bir alandır ve araştırılması gerekmektedir. Ayrıca mev cut kanıtların güçlendirilmesi ve net bir tedavi protokolünün tanımlanması için metodolojik olarak kaliteli araştırmalara ihtiyaç vardır.Conference Object Perceived and Performed Dual-Task Ability in Persons With Multiple Sclerosis: an International Multi-Centered Study(Sage Publications Ltd, 2024) Abasiyanik, Zuhal; Pedulla, Ludovico; Soler, Bernardita; Santoyo-Medina, Carme; Kahraman, Turhan; D'Hooge, Mieke; Tacchino, Andrea[No abstract available]Conference Object A Potential Link Between Chronic Tobacco Smoking and Impaired Visuospatial Memory in People With Multiple Sclerosis(Sage Publications Ltd, 2024) Kahraman, Turhan; Kara, Irem; Unal, Gozde Deniz; Simsek, Yasemin; Ozakbas, SerkanConference Object Prevalence and Correlates of Fear of Falling in People with Multiple Sclerosis Exhibiting No to Mild Disability(Sage Publications Ltd, 2024) Abasiyanik, Zuhal; Ertekin, Ozge; Kara, Tugce; Kahraman, Turhan; Ozakbas, SerkanConference Object Prevalence and Impact of Pain on Quality of Life in a Large Multiple Sclerosis Cohort: A Cross-Sectional Study(Sage Publications Ltd, 2025) Alizada, Said; Ozdogar, Asiye Tuba; Kara, Irem; Kahraman, Turhan; Ozakbas, SerkanArticle Citation - WoS: 1Citation - Scopus: 3Reliability and Construct Validity of Three Self-Report Questionnaires Assessing Dual-Task Difficulties in People With Multiple Sclerosis: an International Study(W B Saunders Co-elsevier inc, 2025) Abasiyanik, Zuhal; Pedulla, Ludovico; Kahraman, Turhan; D'Hooge, Mieke; Santoyo-Medina, Carme; Soler, Bernardita; Feys, PeterObjective: To evaluate the reliability and validity of the dual-tasking questionnaire (DTQ), dual-task screening list (DTSL), and dual-task impact on daily life activities questionnaire (DIDA-Q). Design: Multicenter, cross-sectional study Setting: Persons with multiple sclerosis (pwMS) were recruited from 7 multiple sclerosis centers across 6 countries (Belgium, Chile, Italy, Israel, Spain, and Turkey). Participants: A total of 356 pwMS (mean age 47.5 +/- 11.5y, expanded disability status scale, 3.79 +/- 1.83) were enrolled. Interventions: Not applicable Main Outcome Measures: The reliability (internal consistency, test-retest, and measurement error) and construct validity (structural and convergent) were assessed. Results: The DTQ, DTSL, and DIDA-Q demonstrated excellent test-retest reliability (intraclass correlation coefficients [95% CI], 0.84 [0.80-0.87] to 0.90 [0.87-0.92]) and internal consistency (Cronbach a: 0.86-0.96). As hypothesized, the 3 questionnaires showed a strong correlation with each other, moderate-to-strong correlations with other self-report questionnaires (perceived walking difficulties, fatigue, and fear of falling), and low- to-moderate correlations with cognitive information processing speed, manual dexterity, and dual-task walking performance (walking with word list generation task), showing convergent validity. The DIDA-Q exhibited systematically superior properties. These results were also verified in subsets from 6 different countries. In the structural validity analysis, all questionnaires displayed 2 main factors, allocated as "motor-driven" and "cognitive-driven" subscales. Conclusions: The DTQ, DTSL, and DIDA-Q have good-to-excellent measurement properties, with the highest properties observed in DIDA-Q. The use of these self-reported questionnaires can be used in research and clinical practice to assess the effect of dual-task difficulties on the daily life of ambulatory pwMS. (c) 2024 by the American Congress of Rehabilitation Medicine.Article Six-Spot Step Test Under Three Different Task Conditions To Assess Dual-Task Ability in People With Multiple Sclerosis(Taylor & Francis Ltd, 2025) Ertekin, Ozge; Abasiyanik, Zuhal; Kahraman, Turhan; Dastan, Seda; Ozakbas, SerkanBackground: The Six-Spot Step Test (SSST) is a valid measure to assess the ability of people with multiple sclerosis (pwMS) to maintain balance whilst challenging stability during walking. This study aimed to compare the performance of three different SSST conditions in pwMS and healthy controls (HC) and to explore whether incorporating cognitive tasks into the SSST improves its discriminative capacity by increasing cognitive load. Methods: Fifty-two pwMS (median EDSS = 1.75) and 19 HC were recruited. Participants performed the SSST under three different task conditions: conventional SSST, SSST with word-list generation task (WLG), and SSST with the serial-7 backward task. The dual-task cost (DTC) was calculated for two cognitive task conditions. Results: There was a significant difference across different SSST conditions in both groups. There was also significant condition*group interaction [F (2,132) = 3.69, p = 0.028, eta(2) = 0.053]. PwMS completed all SSST conditions in a longer duration compared to HC. The DTC of SSST with backward and WLG tasks was greater in the MS group than in HC. However, there was no significant differences in the number of correct answers during the dual-task conditions between pwMS and HC. All three conditions showed excellent discriminative ability between pwMS and HC (Area Under Curve value > 0.8). Significance: The SSST had the ability to discriminate between pwMS and HC in both conventional method and with secondary cognitive task. The SSST could be used to evaluate early walking and dual-task deficits even in pwMS with mild disability for future research and clinical practice.Article Sustained Attention and Gait Pattern Changes During the 6-Minute Walk Test in Persons with Multiple Sclerosis(Lippincott Williams & Wilkins, 2025) Abasiyanik, Zuhal; Kahraman, Turhan; Veldkamp, Renee; Ertekin, Ozge; Kalron, Alon; Ozakbas, Serkan; Feys, PeterBackground and purpose: It is unknown whether persons with multiple sclerosis (pwMS) can retain sustained attention and gait quality during long-distance walking tests. This study aimed to investigate changes in sustained attention and gait parameters during prolonged walking in pwMS with different levels of disability and healthy controls (HCs) and correlations of these changes with self-reported daily life difficulties. Methods: The 6-Minute Walk Test was performed with an auditory sustained attention task while wearing inertial measurement sensors. Participants were asked to respond verbally as quickly as possible to randomly presented auditory stimuli during 6 minutes of walking. The accuracy of answers, average reaction time, and gait parameters per minute were determined. Results: Thirty pwMS with mild disability (Expanded Disease Status Scale [EDSS] < 4.0), 16 pwMS with moderate-to-severe disability (EDSS 4.0 to 6.5), and 27 age-gender matched HCs were included. A significant group-by-time interaction effect as found for reactions times, which increased in mild and moderate-to-severe disability groups but not in HCs. Gait parameters deteriorated over time in all groups, but no significant group-by-time interaction was found. The decrease in sustained attention was not related to changes in gait or clinical outcomes, while deterioration in gait parameters was associated with perceived walking disability and dual-task difficulties in daily life. Discussion and Conclusions: Sustained attention during walking declined over time in pwMS, but not in HCs. However, gait parameters deteriorated in all groups. Worsening gait during simultaneous cognitive task execution may contribute to walking and dual-task difficulties in pwMS.Conference Object Tracking Walking Capacity in People With Multiple Sclerosis Without Disability: 3-Year Follow-Up of Objective and Subjective Gait Measures(Sage Publications Ltd, 2025) Abasiyanik, Zuhal; Baba, Cavid; Yigit, Pinar; Samadzade, Ulvi; Kahraman, Turhan; Ozakbas, SerkanConference Object Validation of the Spinal Cord Injury-Falls Concern Scale in Wheelchair Users With Multiple Sclerosis(Sage Publications Ltd, 2025) Abasiyanik, Zuhal; Unal, Gozde Deniz; Kahraman, Turhan; Ertekin, Ozge; Ozakbas, Serkan
