PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/2

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Citation - WoS: 6
Citation - Scopus: 7
2db: a Proteomics Database for Storage, Analysis, Presentation, and Retrieval of Information From Mass Spectrometric Experiments
(Biomed Central Ltd, 2008) Allmer, Jens; Kuhlgert, Sebastian; Hippler, Michael
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational analysis is ever-increasing. Data from such an experimental workflow needs to be captured, related and analyzed. Biological experiments within this scope produce heterogenic data ranging from pictures of one or two-dimensional protein maps and spectra recorded by tandem mass spectrometry to text-based identifications made by algorithms which analyze these spectra. Additionally, peptide and corresponding protein information needs to be displayed. Results: In order to handle the large amount of data from computational processing of mass spectrometric experiments, automatic import scripts are available and the necessity for manual input to the database has been minimized. Information is in a generic format which abstracts from specific software tools typically used in such an experimental workflow. The software is therefore capable of storing and cross analysing results from many algorithms. A novel feature and a focus of this database is to facilitate protein identification by using peptides identified from mass spectrometry and link this information directly to respective protein maps. Additionally, our application employs spectral counting for quantitative presentation of the data. All information can be linked to hot spots on images to place the results into an experimental context. A summary of identified proteins, containing all relevant information per hot spot, is automatically generated, usually upon either a change in the underlying protein models or due to newly imported identifications. The supporting information for this report can be accessed in multiple ways using the user interface provided by the application. Conclusion: We present a proteomics database which aims to greatly reduce evaluation time of results from mass spectrometric experiments and enhance result quality by allowing consistent data handling. Import functionality, automatic protein detection, and summary creation act together to facilitate data analysis. In addition, supporting information for these findings is readily accessible via the graphical user interface provided. The database schema and the implementation, which can easily be installed on virtually any server, can be downloaded in the form of a compressed file from our project webpage.
Citation - WoS: 5
Citation - Scopus: 6
Adaptation of Quality of Life Measure for Limb Lymphedema-Arm in Turkish Women With Breast Cancer-Related Lymphedema
(Lippincott Williams & Wilkins, 2021) Karayurt, Ozgul; Deveci, Zeynep; Eyigor, Sibel; Inbat, Menekse Ozgur
Background Quality-of-life measures are needed for clinicians and researchers to identify quality of women's life with breast cancer-related lymphedema (BCRL). Objective To adapt Quality of Life Measure for Limb Lymphedema-Arm into Turkish (TR) and to test its validity and reliability. Methods This is a methodological and cross-sectional study and was conducted in the lymphedema outpatient clinic of a university hospital. The study included 109 women with BCRL. After linguistic validity of the scale was achieved, confirmatory factor analyses and known group validity were used to test its construct validity. Reliability of the scale was tested with Cronbach's alpha, item-total correlations, and Spearman-Brown coefficient. Results After linguistic validity was achieved, opinions requested from 5 experts specializing in lymphedema showed that item and content validity indexes of the scale were 1. Fit indexes of confirmatory factor analysis were as follows: chi(2)/df = 1.86, root mean square error of approximation = 0.089, standardized root mean square residual = 0.09, and comparative fit index = 0.81. Known group validity analysis showed a significant difference in the mean scores for the subscales of Quality of Life Measure for Limb Lymphedema-Arm-TR, symptom, function, and body image/appearance in terms of lymphedema stages (P < .05). The internal reliability coefficients for the subscales ranged from 0.78 and 0.86. The item-total correlation coefficients ranged between 0.36 and 0.73. Conclusion Quality of Life Measure for Limb Lymphedema-Arm-TR was found to be valid and reliable in the TR population. It could be used in research to evaluate the quality of life in patients with BCRL. Implications for Practice The scale can be used to evaluate effectiveness of nursing interventions directed toward patients developing breast cancer-related lymphedema in clinical settings and studies.
Citation - WoS: 2
Citation - Scopus: 2
Adjuvant Action of Needle-Shaped Bc Microfibrils
(Springer, 2023) Sür, Özge; Gül, Aytul; Hames, Elif Esin
Bacterial cellulose (BC) is an unbranched biopolymer produced by microorganisms and composed of glucopyranose units linked by beta-1,4 bonds. This study investigates the adjuvant action of needle-shaped BC microfibrils (BCmFs) in vitro using bovine serum albumin (BSA) as a model antigen. BC produced by the static culture of Komagataibacter xylinus was then microparticled (1-5 mu m) by acid hydrolysis and characterized using Dynamic Light Scattering and Scanning Electron Microscopy. Subsequently, Attenuated Total Reflectance-Fourier-Transform Infrared Spectroscopy, cytotoxicity, TNF-alpha (tumour necrosis factor-alpha) and IL-6 (interleukin-6) cytokine secretion, and cellular uptake of the BCmFs-BSA conjugate on the human monocyte cell line (U937) differentiated into macrophages were performed. The microfibrils were determined to be 1-5 mu m in size, needle-shaped, with a zeta potential of - 32 mV. Their conjugation with the model antigen, BSA, was demonstrated by FTIR analysis. In the cytotoxicity assay, BCmFs-BSA in macrophage cells showed high viability (over 70%). Although the highest TNF-alpha cytokine level (113 pg/ml) was obtained with BCmFs-BSA (Bovine serum albumin) conjugate (500 mu g/ml) and was statistically significant (p = 0.0001) compared to the positive control group (BSA-aluminium hydroxide), IL-6 cytokine levels were not statistically different from those in the control group as desired. It has been shown in macrophage-differentiated U937 cells that microbially synthesized BC in the form of needle-shaped microfibrils (BCmFs) has a high cellular uptake capacity and increases the immunogenicity of the antigen. These results demonstrate for the first time that BCmFs have the potential to serve as a vaccine adjuvant.
Citation - WoS: 4
Citation - Scopus: 5
Advanced Nurse-Patient Communication System
(Springer, 2012) Unluturk, Mehmet S.
Effective communication is the most important part of any healthcare organization. For many years, hospital nurse call solutions had been stand-alone systems with occasional integration to pocket paging for outputting patient call alerts to mobile staff. In the late 1990's, technology enabled in-building wireless phones to supplement or replace paging systems as a means of not only sending alerts, but also enabling voice communication between mobile staff and patients. Today's nurse call market requires integration of additional information from location and ADT (admit, discharge, transfer) systems into what have traditionally been nurse call applications. This system information is required not only at the nursing station, pagers, and phones, but also at PC's placed on each patient care floor in hallways, nurse stations, and offices, and at areas away from the patients, including administrator and clinical engineering offices. It is crucial that nurses have the latest patient information in their hand wherever they go in the hospital. In this paper, MatchMaker.NET has been developed to integrate all these technologies into the hospital's LAN to improve nurse-patient communication.
Citation - WoS: 10
Citation - Scopus: 9
Advancements in Platinum Chemotherapy for Metastatic Castration-Resistant Prostate Cancer: Insights and Perspectives
(ELSEVIER SCI LTD, 2024) Akkuş, Erman; Arslan, Çağatay; Ürün, Yüksel
Despite improvements in survival, metastatic castration-resistant prostate cancer (mCRPC) remains a significant clinical challenge. While taxanes, new hormonal agents, radiopharmaceuticals, and PARP inhibitors offer valuable treatment options, this review explores the potential of platinum chemotherapies (carboplatin, cisplatin, and oxaliplatin) as alternative choices. Existing research demonstrates promising preliminary results for platinum-based therapies in mCRPC showing PSA response rates (7.7-95 %) and improved overall survival (8-26.6 months). However, chemotherapy-related cytopenias are a frequent side effect. Further research is underway to evaluate the efficacy of platinum regimens against specific mCRPC histopathological variants, particularly aggressive subtypes where the carboplatin and cabazitaxel combination is already recommended. The unique DNA-targeting action of platinum therapy holds promise for patients with deficient DNA repair (dDDR), especially those with BRCA mutations. This potential is supported by both preclinical and ongoing clinical research. Given the limited success of immunotherapy in mCRPC, researchers are exploring the potential for platinum therapies to enhance its efficacy. Additionally, trials are investigating the synergy of combining platinum therapy with both immunotherapy and PARP inhibitors. Further exploration into the effectiveness of platinum therapies in specific mCRPC subpopulations, particularly those with dDDR, is crucial for optimizing their future use. In conclusion, this review highlights the promising potential of platinum-based chemotherapy as a valuable treatment option for mCRPC. While current evidence is encouraging, ongoing research is essential to further optimize its efficacy, identify optimal combinations with other therapies, and better understand its impact on specific mCRPC subpopulations.
Citation - WoS: 2
Citation - Scopus: 2
Aging Attenuated Theta Response During Multistable Perception
(Wiley, 2023) Küçük, Kurtulus Mert; Mathes, Birgit; Schmiedt-Fehr, Christina; Başar Eroğlu, Canan
Multistable stimuli are physically unchanging, but elicit spontaneous perceptual reversals between multiple internally generated perceptual alternatives. Perceptual reversal rates seem to decrease in older adults; however, there is no literature on the electrophysiological correlates of this performance decrease. Here, we aimed to identify age-related changes in theta activity that relate to decreased reversal rates of older adults. Electroencephalography (EEG) of young (n = 15) and older adults (n = 15) was recorded during presentation of stroboscopic alternative motion (SAM) and a control stimulus. Time-frequency amplitudes were extracted in 4-8 Hz via Morlet wavelet convolution. Older adults had lower SAM reversals as well as decreased accuracy, increased reaction time (RT) and increased RT variability in the control task. In older adults, reversal-related frontal theta response was diminished, yet parietal theta was intact. In the parietal area, the relationship between theta response and reversal rates was robust, but in the frontal area, was dependent on age-related variance. Result indicated that, in older adults, top-down facilitation of perceptual reversals was impaired. This appears to result in a predominantly bottom-up resolution of perceptual multistability. Age-related degradation of sensory areas in this bottom-up-driven resolution process might have slowed reversals. This study presents the first electrophysiological correlates of age-related impairment in multistable perceptual integration.
Citation - WoS: 25
Citation - Scopus: 29
Alterations in Levels of 8-Oxo '-deoxyguanosine and 8-Oxoguanine Dna Glycosylase 1 During a Current Episode and After Remission in Unipolar and Bipolar Depression
(Pergamon-Elsevier Science Ltd, 2020) Ceylan, Deniz; Yilmaz, Selda; Tuna, Gamze; Kant, Melis; Er, Ayse; Ildiz, Aysegul; Verim, Burcu
Introduction: Previous studies showed significant increases in DNA base damage markers and significant alterations in base excision repair enzymes in patients with unipolar and bipolar depression. We aimed to investigate changes in urine 8-Oxo-2'-deoxyguanosine (8-oxo-dG) and gene expression levels of 8-Oxoguanine DNA glycosylase 1 (OGG1) during a current depressive episode and after remission in bipolar and unipolar disorders. Methods: Twenty-four acutely depressed bipolar (BD), 33 unipolar depression (UD) patients and 61 healthy controls were included in the study. Clinical evaluations, blood and urine sampling were completed at baseline and at remission after eight weeks. The urine 8-oxo-dG levels were assessed by liquid chromatography tandem mass spectrometry and adjusted for urine creatinine levels. The gene expression levels of OGG1 were determined from cDNA extracted from blood samples, using real time-polymerase chain reaction. Results: At baseline, patients presented significantly higher levels of 8-oxo-dG (p = 0.008), and lower gene expression of OGG1 (p = 0.024) compared to controls. Levels of either 8-oxo-dG or OGG1 expression did not differ between BD and UD. In patients who remitted by the 8th week (n = 30), 8-oxo-dG decreased significantly (p = 0.001), and gene expression levels of OGG1 increased by 2.95 times compared to baseline levels (p = 0.001). All comparisons were adjusted for age, sex, smoking status and body mass index. Conclusion: Our results suggest that patients with bipolar and unipolar mood disorders present increased 8-oxo-dG and decreased gene expression levels of OGG1 in current depressive episodes, and that these changes might be reversed by the resolution of depressive symptoms. The causal relationship between DNA damage and repair requires further exploration.
Citation - WoS: 10
Citation - Scopus: 11
Alzheimer's Disease Research Progress in the Mediterranean Region: the Alzheimer's Association International Conference Satellite Symposium
(Wiley, 2022) Sexton, Claire; Solis, Michele; Aharon-Peretz, Judith; Alexopoulos, Panagiotis; Yener, Görsev; Bayen, Eleonore; Birkenhager, Betty
As research and services in the Mediterranean region continue to increase, so do opportunities for global collaboration. To support such collaborations, the Alzheimer's Association was due to hold its seventh Alzheimer's Association International Conference Satellite Symposium in Athens, Greece in 2021. Due to the COVID-19 pandemic, the meeting was held virtually, which enabled attendees from around the world to hear about research efforts in Greece and the surrounding Mediterranean countries. Research updates spanned understanding the biology of, treatments for, and care of people with Alzheimer's disease (AD_ and other dementias. Researchers in the Mediterranean region have outlined the local epidemiology of AD and dementia, and have identified regional populations that may expedite genetic studies. Development of biomarkers is expected to aid early and accurate diagnosis. Numerous efforts have been made to develop culturally specific interventions to both reduce risk of dementia, and to improve quality of life for people living with dementia.
Alzheimer's Imaging Consortium
(2025) Gonzalez-Gomez, R.; Hernandez, H.; Migeot, J.; Cruzat, J.; Legaz, A.; Fittipaldi, S.; Ibáñez, A.
BACKGROUND: While education is crucial for brain health, evidence mainly relies on individual measures of years of education (YoE), neglecting educational quality (EQ). Whether YoE and EQ have complementary impacts on aging and dementia is unknown. METHODS: We assessed the impact of EQ and YoE on brain health in 7,533 subjects from 20 countries, including healthy controls (HCs), Alzheimer's disease (AD), and frontotemporal lobar degeneration (FTLD). EQ was based on country-level quality indicators. After applying neuroimage harmonization, we examined their effect on gray matter volume and functional connectivity. Regression models were adjusted for age, sex, and cognition, controlling for multiple comparisons. The impact of image quality was controlled through sensitivity analysis. RESULTS: Less EQ and YoE were associated with greater brain burden across groups. However, EQ had a stronger impact, mainly targeting the vulnerable areas of each condition. At the whole-brain level, EQ influenced atrophy (HCs: ∆mean = 2.0 [1.9-2.0] CL95 × 10⁻², p < 10⁻⁵; AD: ∆mean = 0.1 [-0.0-0.3] CL95 × 10⁻², p = 0.18; FTLD: ∆mean = 3.5 [3.0-4.0] CL95 × 10⁻², p < 10⁻⁵) and networks (HCs: ∆mean = 13.5 [13.2-13.7] CL95 × 10⁻², p < 10⁻⁵; AD: ∆mean = 5.9 [5.2-6.7] CL95 × 10⁻², p < 10⁻⁵; FTLD: ∆mean = 13.2 [11.2-13.7] CL95 × 10⁻², p < 10⁻⁵), 1.3 to 7.0 times more than YoE. CONCLUSION: Results support the need to incorporate education quality to study and improve brain health, underscoring the importance of country-level measures. © 2025 The Alzheimer's Association. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
Citation - WoS: 112
Citation - Scopus: 130
Analysis of High-Dimensional Phase Space Via Poincare Section for Patient-Specific Seizure Detection
(IEEE-Inst Electrical Electronics Engineers Inc, 2016) Zabihi, Morteza; Kiranyaz, Serkan; Rad, Ali Bahrami; Katsaggelos, Aggelos K.; Gabbouj, Moncef; İnce, Türker
In this paper, the performance of the phase space representation in interpreting the underlying dynamics of epileptic seizures is investigated and a novel patient-specific seizure detection approach is proposed based on the dynamics of EEG signals. To accomplish this, the trajectories of seizure and nonseizure segments are reconstructed in a high dimensional space using time-delay embedding method. Afterwards, Principal Component Analysis (PCA) was used in order to reduce the dimension of the reconstructed phase spaces. The geometry of the trajectories in the lower dimensions is then characterized using Poincare section and seven features were extracted from the obtained intersection sequence. Once the features are formed, they are fed into a two-layer classification scheme, comprising the Linear Discriminant Analysis (LDA) and Naive Bayesian classifiers. The performance of the proposed method is then evaluated over the CHB-MIT benchmark database and the proposed approach achieved 88.27% sensitivity and 93.21% specificity on average with 25% training data. Finally, we perform comparative performance evaluations against the state-of-the-art methods in this domain which demonstrate the superiority of the proposed method.
The Anatomy of a Decision: Exploring the Push, Pull, and Personal Factors of Emigration Intent Among Turkish Medical Students
(BMC, 2025) Aydin, Mevlut Okan; Caliskan, S. Ayhan; Ozkaya, Guven; Kumtepe, A. Sila; Aydin, Birnur; Alper, Zuleyha
BackgroundThe migration intentions of medical students, often referred to as "brain drain," pose a significant challenge to healthcare systems worldwide. This study aims to investigate the motivations for emigration, career preferences, and preparatory actions among medical students in T & uuml;rkiye, a country experiencing significant physician outflow. Methods A cross-sectional online survey was distributed to medical students across T & uuml;rkiye. The final sample included 1134 participants from 20 different medical faculties. Data were collected on demographics, motivations for studying medicine, specialty preferences, language proficiency, international experience, and intentions and preparations for working abroad or domestically. Results Motivations for studying medicine and specialty preferences differed significantly by gender. Female students were more driven by altruism and preferred nonsurgical specialties, whereas male students prioritized financial prospects, prestige, and surgical fields. The key predictors for intending to work abroad included higher parental education, advanced foreign language proficiency (especially English), and prior international experience. A third of the students (33%) expressed a desire to work abroad after graduation, with Germany, the UK, and the US being the top destinations. The primary push factors for emigration were demanding working conditions (70.8%), violence against healthcare professionals (64.1%), and systemic problems within the healthcare system (55.8%). A striking finding was 74.2% of the students who planned to stay in T & uuml;rkiye were also making preparations to leave, indicating a deep-seated lack of confidence in the domestic healthcare environment. Conclusion A significant proportion of Turkish medical students intend to practice abroad, driven primarily by push factors related to working conditions and safety. The widespread preparatory activities, even among those stating an intention to stay, suggest that brain drain is a tangible risk. Retaining this future physician workforce requires urgent, systemic interventions addressing working conditions, safety from violence, and career opportunities, particularly in research and academic medicine.
Citation - WoS: 27
Citation - Scopus: 35
Artificial Intelligence and Radiomics in Nuclear Medicine: Potentials and Challenges
(Springer, 2019) Aktolun, Cumali
Artificial intelligence involves a wide range of smart techniques that are applicable to medical services including nuclear medicine. Recent advances in computer power, availability of accumulated digital archives containing large amount of patient images, and records bring new opportunities for the implementation of artificial techniques in nuclear medicine. As a subset of artificial intelligence, machine learning is an emerging tool that can possibly perform many clinical tasks. Nuclear medicine community needs to adapt to this fast approaching smart era, to exploit the opportunities and tackle the problems associated with artificial intelligence tools. It is aimed in this editorial to outline the opportunities and challenges of artificial intelligence applications in nuclear medicine.
Artificial Intelligence and Radiomics in Nuclear Medicine: Potentials and Challenges (vol 46, Pg 2731, 2019)
(Springer, 2020) Aktolun, Cumali
[Abstract Not Available]
Aso Visual Abstract: Breast Cancer Recurrence in Initially Clinically Node-Positive Patients Undergoing Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in the Neosentiturk-Trials Mf18-02/18-03
(Springer, 2025) Cabioglu, N.; Karanlik, H.; Igci, A.; Muslumanoglu, M.; Gulcelik, M.A.; Uras, C.; Ozmen, V.
Citation - WoS: 11
Citation - Scopus: 11
Assessing Safety and Efficacy of Tnfi Treatment in Late Onset Ankylosing Spondylitis: a Turkbio Registry Study
(Nature portfolio, 2024) Uslu, Sadettin; Gülle, Semih; Şen, Gercek; Cefle, Ayşe; Yılmaz, Sema; Koçer, Sinem Burcu; Yüce İnel, Tuba
Clinical data on the use of tumour necrosis factor inhibitors (TNFi) in late-onset ankylosing spondylitis (LoAS) are limited. The present study aimed to evaluate efficacy, safety, and treatment adherence associated with the initial use of TNFi therapy in biologic naive patients diagnosed with LoAS. Patients whose age of onset was >= 45 years and < 45 years were classified as having LoAS and YoAS, respectively, based on the age of symptom onset. There were 2573 patients with YoAS and 281 LoAS. Baseline disease activity measures were similar between the groups. No significant differences were seen between the two groups in response to treatment and in remaining on the first TNFi at 6, 12 and 24 months. In the LoAS group, the analysis showed that TNFi discontinuation was linked to VAS pain score (HR 1.04; 95% CI 1.01-1.06). Patient groups had similar rates of adverse events (YoAS: 8.7% vs. LoAS: 11.7%). In both biologic naive LoAS and YoAS patients, the study showed that the initial TNFi therapy was equally effective and safe.
Citation - WoS: 8
Citation - Scopus: 13
Assistive Technologies for Visually Impaired Individuals in Turkey
(R E S N A Press, 2010) Bengisu, Murat
A phone survey was conducted with 80 visually impaired people in Turkey to understand what types of assistive products are used and to what extent. The perceived utility of selected products and reasons for nonuse were investigated. Descriptions of products that would be useful for the participants but may not be available on the market were also obtained. The three most used assistive products were found to be computer screen readers (46%), talking watches (26%), and screen readers for cellular phones (21%). Cellular phones with screen reading capability are the most desired assistive products among the visually impaired community, but their high cost is a major barrier. Most of the relevant technologies are available but some product development, such as adaptation to the Turkish language, is necessary. The three products most frequently requested are bus station/destination announcement systems, devices that warn the person about barriers, and devices that read printed documents and signs.
Citation - WoS: 8
Citation - Scopus: 9
The Association Between Mobile Phone Usage Duration, Neck Muscle Endurance, and Neck Pain Among University Students
(NATURE PORTFOLIO, 2024) Elvan, Ata; Çevik, Şeval; Vatansever, Kivanc; Erak, İlknur
The mobile phone is essential in daily life, especially during the pandemic. Prolonged use can cause postural issues, leading to common neck pain. This study aims to determine the correlation between mobile phone use duration, addiction, neck muscle endurance, and neck pain in university students. The study included 62 participants (30 female, 32 male) aged 18-35 years. Inclusion criteria required participants to have experienced neck pain at least twice in the past year and to have no other concomitant issues, as well as to volunteer for the study. Demographic information and daily mobile phone usage time were collected. Neck pain was assessed with the Visual Analogue Scale, smartphone addiction with the Smartphone Addiction Scale, and cervical muscle endurance was evaluated. Correlation analysis reveals a moderate relationship between neck pain severity (NPS) and cervical extensor muscle endurance (CEME), a strong relationship between NPS and cervical flexor muscle endurance (CFME), as well as a strong relationship among daily phone usage time (DPUT), CFME, and NPS, with a moderate relationship between DPUT and CEME. Participants were divided into two groups based on their DPUT, revealing that those who used their phone for four hours or more showed significantly higher levels of pain (p < 0.05) and reduced endurance in cervical flexor muscles. Our study found a strong correlation between neck pain, muscle endurance, and daily phone usage. Participants using their phones for more than four hours daily reported increased neck pain and decreased muscle endurance. We suggest integrating phone usage duration into neck pain assessments, promoting ergonomic practices, and offering detailed usage guidelines for users.
Citation - WoS: 76
Citation - Scopus: 87
The Associations of Dyadic Coping and Relationship Satisfaction Vary Between and Within Nations: a 35-Nation Study
(Frontiers Media Sa, 2016) Hilpert, Peter; Randall, Ashley K.; Sorokowski, Piotr; Atkins, David C.; Sorokowska, Agnieszka; Ahmadi, Khodabakhsh; Aghraibeh, Ahmad M.; Dural, Seda
Objective: Theories about how couples help each other to cope with stress, such as the systemic transactional model of dyadic coping, suggest that the cultural context in which couples live influences how their coping behavior affects their relationship satisfaction. In contrast to the theoretical assumptions, a recent meta-analysis provides evidence that neither culture, nor gender, influences the association between dyadic coping and relationship satisfaction, at least based on their samples of couples living in North America and West Europe. Thus, it is an open questions whether the theoretical assumptions of cultural influences are false or whether cultural influences on couple behavior just occur in cultures outside of the Western world. Method: In order to examine the cultural influence, using a sample of married individuals N = 7973) from 35 nations, we used multilevel modeling to test whether the positive association between dyadic coping and relationship satisfaction varies across nations and whether gender might moderate the association. Results: Results reveal that the association between dyadic coping and relationship satisfaction varies between nations. In addition, results show that in some nations the association is higher for men and in other nations it is higher for women. Conclusions: Cultural and gender differences across the globe influence how couples' coping behavior affects relationship outcomes. This crucial finding indicates that couple relationship education programs and interventions need to be culturally adapted, as skill trainings such as dyadic coping lead to differential effects on relationship satisfaction based on the culture in which couples live.
Citation - Scopus: 4
The Associations of Dyadic Coping and Relationship Satisfaction Vary Between and Within Nations: a 35-Nation Study (Vol 7, Pg 1106, 2016)
(Frontiers Media Sa, 2016) Hilpert, Peter; Randall, Ashley K.; Sorokowski, Piotr; Atkins, David C.; Sorokowska, Agnieszka; Ahmadi, Khodabakhsh; Yoo, Gyesook; Dural, Seda
Citation - WoS: 1
Citation - Scopus: 1
Attitudes of Oncology Nurses Regarding Ageism
(Springer, 2022) Curuk, Gulsum Nihal; Ozgul, Ecem
Purpose Ageism is reported to have negative impacts on older cancer patients' health and wellbeing. Nurses' attitudes to ageism influence the quality of care of older cancer patients and the prognosis of the disease. The aim of this descriptive and quantitative study was to determine oncology nurses' attitudes regarding ageism. Methods Data were collected online by using a sociodemographic and clinical features form developed in light of the literature and the Ageism Attitude Scale. The data collection tools were filled in by 237 oncology nurses between June and September in 2020. Obtained data were analyzed with mean, standard deviation, numbers, percentages, independent samples t-test, one-way analysis of variance, and Pearson's correlation analysis. Results The mean score of the oncology nurses on the Ageism Attitude Scale was 87.76 +/- 9.22 (ranging from 63 to 111), and their attitudes to old age were positive. The mean scores of the nurses on the subscales were as follows: 37.45 +/- 4.69 for restricting life of the elder, 30.05 +/- 5.27 for positive discrimination, and 20.30 +/- 4.58 for negative discrimination. Also, 75.94% of the nurses experienced difficulty in offering care to older patients. The mean score of the nurses on the Ageism Attitude Scale significantly differed in terms of age, duration of work experience, staying with older people, and financial status (p < 0.05). Conclusions The study revealed that the oncology nurses generally had positive attitudes to older people. Incorporation of geriatrics related topics into both undergraduate education and in-service training could help to maintain positive attitudes to older people and prevent unfavorable attitudes to them. It can also be recommended that attitudes of health professionals to ageism should be evaluated by older people in further studies.

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