TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/4
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Article Fluorescence Microscopy Denoizing Via Neighbor Linear Embedding(Istanbul University, 2024-01-31) Kırmızıay, Çağatay; Aydeniz, Burhan; Türkan, MehmetOne of the difficulties in studying fluorescence imaging of biological structures is the presence of noise corruption. Even though hardware- and software-related technologies have undergone continual improvement, the unavoidable effect of Poisson–Gaussian mixture type is generally encountered in fluorescence microscopy images. This noise should be mitigated to allow the extraction of valuable information from fluorescence images for various types of biological analysis. Thus, this study introduces a new and efficient learning-based denoizing approach for fluorescence microscopy. The proposed approach is based mainly on linear transformations between noise-free and noisy submanifold structures of patch spaces, benefiting from linear neighbor embeddings of local image patches. According to visual and statistical results, the developed algorithm called "neighbor linear-embedding denoizing" algorithm has a highly competitive and generally superior performance in comparison with the other algorithms used for fluorescence microscopy image denoizing in the literature. © 2024 Istanbul University. All rights reserved.Article Preantral Follicle Morphometry and Ultrastructure of Antral Follicles in Anatolian Water Buffalo(TUBITAK, 2023-10-17) Bakı, Acar, D.; Bırdane, M.K.; Tokyol, Ç.; Göçmen, Karabekır, N.N.; Hayran, Mürvet; Özenç, E.; Aktepe, F.; Uçar, Mehmet; Hayran, Hatice Mürvet; Göçmen Karabekır, Nermin Nüket; Bakı Acar, Duygu; Karabekir, Nermin Nuket Gocmen; Yağcı, İlknur Pir; Yazıcı, Ebubekir; Mas, Nuket Gocmen; Acar, Duygu BakiThis study aimed to evaluate quantitative and morphometric analyses of preantral follicles and the ultrastructural characteristics of antral follicles in different oestrous cycle stages in Anatolian water buffaloes. Twenty-four ovaries collected from twelve slaughtered Anatolian water buffaloes were classified macroscopically as luteal or follicular stages. The ovaries were prepared for histological examination (Hematoxylin-eosin staining), and primordial, primary, and secondary follicle numbers were calculated, and the diameters of oocytes, follicles, and nuclei were measured under a light microscope with a micrometre. The theca and granulosa cells of antral follicles were observed under a transmission electron microscope. The mean number of preantral follicles was 18584 ± 4855, and there was a significant difference in the number of primordial follicles (p < 0.0001) and primary follicles (p < 0.001) between buffaloes. The number of primordial follicles was 10,636, that of primary follicles was 6514, and that of secondary follicles was 1434; the statistical difference was found between primordial, primary, and secondary follicle and oocyte diameters (p < 0.001) in Anatolian water buffaloes. In this study, the ultrastructural evaluation of antral follicles showed that the theca cells were active in the luteal stage with their functional organelles and higher lipid droplets. The granulosa cells were still inactive in the luteal stage. In the follicular stage of the oestrous cycle, the theca cells were found inactive, although granulosa cells showed moderate or high activity. It was found that the serum progesterone concentration and cycle stage directly affected the theca and granulosa cell ultrastructural activity in Anatolian water buffalo. In this research, information from light and electron microscopic analyses of preantral and antral follicles has been obtained for the first time for Anatolian water buffaloes. The result of our study suggests that detailed molecular research is needed to evaluate the ultrastructural activity of antral follicles in different oestrous cycle stages and steroidogenic circumstances. © TÜBİTAK.Article Citation - WoS: 2Citation - Scopus: 2Testing the Concealed Ovulation Hypothesis in the Framework of Facial Symmetry Fluctuations Moderated by Menstrual Cycle in Women(Turkish Psychologists Assoc, 2010) Çeti̇nkaya, Hakan; Dural, Seda; Gulbetekin, Evrim; Çetinkaya, Seda DuralWith three studies, a long lived position that women have concealed ovulation, and its possible adaptive value were investigated. In the first study, systematic changes in women across the menstural cycle were elaborated and of those, cyclic changes in the facial symmetry in regularly ovulating women were investigated. The findings showed predictable fluctuations on females' facial symmetry throughout their menstural phases. In order to determine whether the differences among the deviation from the symmetry scores of the facial pictures obtained from four menstural phases (namely, menstural, proliferative, ovulatory, and secretory phases) were detectable by males, in the second experiment, males evaluated the facial-menstural pictures for their attractiveness. The male participants rated the pictures obtained from ovulatory phases as the most attractive of all. Also they found the pictures obtained from the menstural phases to be least attractive. In the third study, half of the male participants (familiar males) rated four menstural pictures obtained from the same females, the other half of them (unfamiliar males) rated four menstural pictures, but this time each of which obtained from different females. The males in the latter group were not able to distinguish attractiveness of the facial pictures of different females. The results indicate that although there is some extent of concealment of ovulation in women as an adaptation, it is not completely concealed, especially from the familiar (or pair-bonded) males. Thus, men might have equipped with a counter-adapt, a mental device, through their evolutionary history to cope with the problem of concealment of ovulation in women by staying with her and observing the cyclic changes on her facial attractiveness.