Search Results

Now showing 1 - 1 of 1

Citation - WoS: 1
G-Quadruplex Enrichment Analysis Reveals Their Role as Intronic Regulatory Elements in Plants
(Tubitak Scientific & Technical Research Council Turkey, 2019-03-07) Doluca, Osman
G-Quadruplexes, a class of noncanonical but highly stable nucleic acid structures, have the potential to be part of the regulatory mechanism of cells. They can form in the genome where the double-stranded helix is unwound to facilitate formation of a G-quadruplex. The biological significance of these structures is yet to be understood entirely. This work presents a novel approach and investigates common characteristics in the distribution of G-quadruplexes relative to genes in plants through analysis of genomes and gene expressions. The results indicate that G-quadruplex distribution has gone through significant changes with the evolution of higher plants and, for the first tune, that G-quadruplexes enriched at the beginning of introns may have a regulatory role during transcription.

TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection