TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/4
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Letter Response to: Effectiveness of a Program to Raise Awareness About Pneumococcal Vaccination Among Physicians and Patients with Chronic Respiratory Diseases: A Multicenter Cohort Study(Galenos Publ House, 2025-06-03) Şimşek, Nurdan; Altın, Sedat; Sayiner, Abdullah; Yalnız, Enver; Karakurt, Zuhal; Kul, Seval; Uslu, Ozgur; Veske, Nurdan Simsek; Karakut, Zuhal; Oruc, OzlemArticle Citation - WoS: 7Citation - Scopus: 7Effectiveness of a Program To Raise Awareness About Pneumococcal Vaccination Among Physicians and Patients With Chronic Respiratory Diseases: a Multicenter Cohort Study(AVES, 2024-08-27) Karakurt, Z.; Yalnız, E.; Altın, S.; Oruç, Ö.; Uslu, Ö.; Veske, N.Ş.; Kılınç, O.; Sayıner, Abdullah; Kul, Seval; Şimşek, NurdanOBJECTIVE: There is a need to increase patient and clinician awareness on the effectiveness of pneumococcal vaccination in at-risk groups. The aim of the study was to evaluate the effect of reminders for physicians and patients using the vaccination tracking system created in the hospital information management system (HIMS) on the vaccination rate, and the effect of pneumococcal vaccination on pneumonia-related hospitalization and mortality over a 12-month period. MATERIAL AND METHODS: This prospective observational cohort study was undertaken during a 2-year period in 3 tertiary care cen-ters. Patients were followed up for 12 months following vaccination, and hospital admissions and mortality were recorded via HIMS. During the campaign, HIMS transmitted pneumococcal immunization reminder messages in accordance with guideline recommendations to physicians’ computers and patients’ mobile phones. Educational posters on pneumococcal vaccination were posted in outpatient clinics. Regular seminars on the evidence for pneumococcal vaccination were organized. All patients who were hospitalized during the follow-up period for chronic obstructive pulmonary disease (COPD), asthma, lung cancer, or pneumonia were analyzed in relation to their vaccination history regarding clinical outcomes. RESULTS: A total of 29 530 patients were included in the study. During the study period, the annual vaccination rate increased by 74.4% and reached 4.8% in 3 hospitals (P = .001). The rates were 3.9% in patients older than 65 years without comorbidities and 5.2% in those with COPD and asthma (P = .002). In pneumococcal vaccine recipients, pneumonia-related hospital mortality was lower (relative risk (RR) = 0.19, CI 0.09-0.35, P < .001). CONCLUSION: It is possible to raise the rate of pneumococcal vaccination through awareness campaigns. Individuals with COPD and asthma are more willing to receive pneumococcal vaccination. Among patients hospitalized for pneumonia, prior pneumococcal vaccination is associated with lower mortality. © Author(s).Article Cardiac Functions and Peripheral Arterial Stiffness in Patients With Polycystic Ovary Syndrome: a Cross-Sectional Study(Galenos Publ House, 2023-08-01) Colak, Ayse; Ozpelit, Mehmet Emre; Okyay, Emre; Kumral, Zeynep; Özpelit, Ebru; Okyay, Recep EmreBACKGROUND/AIMS: Polycystic ovary syndrome (PCOS) patients have been described as having subclinical cardiac and vascular damage; nevertheless, research data is contradictory. We aimed to assess global cardiac functions, peripheral arterial stiffness (AS), and the relationships between echocardiographic and AS measurements in patients with PCOS. MATERIALS AND METHODS: We enrolled 42 consecutive PCOS patients and 32 age- and body mass index (BMI)-matched healthy controls. All participants underwent a comprehensive two-dimensional echocardiographic examination. Applanation tonometry was utilized to determine peripheral AS [carotid-radial pulse wave velocity (PWV) and augmentation index (AIx)] in each participant. In addition, we evaluated the correlation between AS and echocardiographic parameters. RESULTS: The PCOS and control groups had similar ages and BMIs. Right ventricular (RV) and left ventricular (LV) diameters, LV mass, and LV ejection fraction were similar between the groups. Considering the pulse wave and tissue Doppler parameters of the cardiac functions, the LV septal S’, LV Tei index, RV S’, RV Tei index, and E/E’ ratio were comparable between the two groups. Peripheral AS parameters including, PWV and AIx were higher in those patients with PCOS [19.3±12.5 vs. 12.5±9.6; p=0.01 and 5 (4.7-5.5) vs. 4.4 (4.2-4.8); p=0.0001, respectively]. AS parameters were not correlated with echocardiographic parameters. CONCLUSION: Despite normal echocardiographic LV and RV functions, women with PCOS had increased AS. There was no correlation between echocardiographic and AS parameters in these patients.Article Citation - WoS: 6Citation - Scopus: 10Comparison of Bpap S/T and Average Volume-Assured Pressure Support Modes for Hypercapnic Respiratory Failure in the Emergency Department: a Randomized Controlled Trial(Galenos Publ House, 2021-09-22) Gören, Nurfer Zehra; Sanci, Emre; Coskun, Feride Fulya Ercan; Gursoylu, Duygu; Bayram, BasakBackground: There is limited research into the utility of average volume-assured pressure support (AVAPS), a volume-assured pressure-controlled mode, especially in patients with hypercapnic respiratory failure. Aims: This study aimed at a randomized comparison of AVAPS and bilevel positive airway pressure spontaneous/timed (BPAP S/T) modes in non-invasive mechanical ventilation (NIMV) application with hypercapnic respiratory failure patients in the emergency department (ED). Study Design: Randomized controlled study. Methods: In this prospective randomized controlled study, 80 patients admitted to ED with hypercapnic respiratory failure requiring NIMV were randomly assigned to AVAPS or S/T groups using the sealed envelope method (33 patients in the S/T group, 47 patients in the AVAPS group). Data of arterial blood gas (ABG), vital parameters, Glasgow Coma Score (GCS), additional treatment needs, and clinical outcomes were evaluated, and the treatment success rates of both groups were compared. Results: A total of 80 patients, 33 in the S/T and 47 in the AVAPS group, were analyzed in the study. The pH values improved in the AVAPS group compared to the baseline (0.07 [0.04-0.10] vs 0.03 [0.00-0.11]). PaCO2 (partial pressure of carbon dioxide) excretion was faster in the AVAPS group than in the S/T group in the first hour (10.20 mmHg [6.20-19.20] vs. 4.75 ([-] 0.83-16.88)). The comparison of blood gas measurements showed no significant differences between the groups regarding the changes in PaCO2 and pH values over time (P=.141 and P=.271, respectively). During the ED follow-up, 3 (6.4%) patients in the AVAPS group and 5 (15.2%) patients in the S/T group needed intubation [Relative risk: 0.42 (95% CI: 0.11 to 1.64), P=.21]. Conclusion: In this study, improvements in blood gas parameters in the AVAPS group were faster compared to the S/T group; however, we did not find any significant difference between the groups in terms of clinical parameters. The AVAPS mode is as effective and safe as BPAP S/T in treating patients with hypercapnic respiratory failure in the ED.Letter In Response To Comment on Average Volume-Assured Pressure Support Modes for Hypercapnic Respiratory Failure Its Early Use in the Emergency Department(Galenos Publ House, 2021-03-15) Goren, Nurfer[Abstract Not Available]