TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/4
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Article User-Centered Approaches in Conventional and Autonomous Truck Design and Future Effects on Environmental Design(2022-04-30) Dilaver, Nimet; Küçükerman, Önder; Hasırcı, DenizMeeting the world’s increasing need for transportation today soon requires the development of autonomous vehicle systems. User-centered approaches in industrial design are crucial to advance technological, mechanical, and equipment specifications and provide effective driving experiences. This study analyzes conventional and new generation autonomous vehicles through user-centered design (UCD) and drivers’ experiences. Turkish company BMC and the new truck series “Tuğra” are selected. Participants are truck drivers, designers, engineers, and specialists. Observations and face-to-face interviews investigated comfort, usefulness, usability, desirability, accessibility, credibility, findability, and value from the elements of user experience design within the truck, as well as users’ awareness of UCD. Credibility and usability were among the highest-ranked principles. The participants provided valuable information for the design development of trucks, and ideas for future problems and solutions. Further multidisciplinary research that focuses on technical, as well as social and ethical issues is essential in this new and emerging area.Article Citation - WoS: 3Citation - Scopus: 3A Minimally Invasive Transfer Method of Mesenchymal Stem Cells To the Intact Periodontal Ligament of Rat Teeth: a Preliminary Study(Tubitak Scientific & Technical Research Council Turkey, 2018-10-25) Gul Amuk, Nisa; Kurt, Gokmen; Kartal Yandim, Melis; Adan, Aysun; Baran, Yusuf; Amuk, Nisa Gul; Yandım, Melis KartalThe aim of this study was to introduce a minimally invasive procedure for mesenchymal stem cell (MSC) transfer into the intact periodontal ligament (PDL) of the molar teeth in rats. Ten 12-week-old Wistar albino rats were used for this preliminary study. MSCs were obtained from bones of two animals and were labeled with green fluorescent protein (GFP). Four animals were randomly selected for MSC injection, while 4 animals served as a control group. Samples were prepared for histological analysis, Cox-2 mRNA expression polymerase chain reaction analysis, and fluorescent microscopy evaluation. The number of total cells, number of osteoclastic cells, and Cox-2 mRNA expression levels of the periodontal tissue of teeth were calculated. The number of total cells was increased with MSC injections in PDL significantly (P < 0.001). The number of osteoclastic cells and Cox-2 mRNA expression were found to be similar for the two groups. GFP-labeled MSCs were observed with an expected luminescence on the smear samples of the PDL with transferred MSCs. The results of this preliminary study demonstrate successful evidence of transferring MSCs to intact FIX in a nonsurgical way and offer a minimally invasive procedure for transfer of MSCs to periodontal tissues.