Özpelit, Mehmet Emre

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Profile URL
https://hdl.handle.net/20.500.14365/6954
Name Variants
Ozpelit, Mehmet Emre
Özpelit M.E
Job Title
Email Address
emre.ozpelit@ieu.edu.tr
Main Affiliation
09.02. Internal Sciences
Status
Current Staff
Website
ORCID ID
0000-0003-3470-0219
Scopus Author ID
6505504017
Turkish CoHE Profile ID
8DD82FB47F4A5C37
Google Scholar ID
MZ_uVVQAAAAJ
WoS Researcher ID
AIB-9567-2022

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26

Citations

226

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7

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34

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Scholarly Output

4

Articles

4

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3/19

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

5

Scopus Citation Count

5

WoS h-index

2

Scopus h-index

2

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0

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0

WoS Citations per Publication

1.25

Scopus Citations per Publication

1.25

Open Access Source

3

Supervised Theses

0

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JournalCount
Cyprus Journal of Medical Sciences1
Diagnostics1
European Review for Medical and Pharmacological Sciences1
Türk Kardiyoloji Derneği Arşivi — Archives of the Turkish Society of Cardiology1
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Now showing 1 - 4 of 4
  • Thumbnail Image
    Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Myocardial Infarction in Young Adults: Diagnosis Begins Through Inspection
    (2024) Özpelit, Mehmet Emre; Kumral, Zeynep; Özpelit, Ebru; Çolak, Ayse
    Spontan koroner arter diseksiyonu (SKAD), genellikle orta yaşlı kadınları etkileyen nadir bir akut koroner sendrom formudur. Genetik vaskülopatiler de dahil olmak üzere bağ dokusu hastalıkları SCAD’ye yol açan önemli predispozan durumlardan biridir. Bu yazıda, anterior miyokard enfarktüsü geçiren ve vasküler tip Ehler-Danlos sendromu tanısı alan 36 yaşında bir erkek hasta sunulmuş ve literatür gözden geçirilmiştir.
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    Article
    Citation - WoS: 2
    Citation - Scopus: 2
    Correlation and Agreement Between the Score2 and Prevent 10-Year Atherosclerotic Cardiovascular Disease Risk Scores: Insights From Coronary Computed Tomography Angiography
    (Mdpi, 2024) Ozpelit, Mehmet Emre; Colak, Ayse; Uzumcu, Hatice Irem; Kumral, Zeynep; Ozpelit, Ebru
    Background: We aimed to evaluate the correlation and agreement between the Systemic Coronary Risk Estimation 2 (SCORE2) and Predicting Risk of CVD EVENTs (PREVENT) 10-year ASCVD risk scores by incorporating computed tomographic (CT) data to assess differences between the scoring systems. Methods: The PREVENT risk score was calculated for 171 patients, while the SCORE2 and SCORE2 Older Persons (OP) risk scores were calculated for 113 patients. Coronary artery calcium (CAC) scores were calculated, and the grading of coronary artery disease (CAD) was assessed according to these scores. Results: According to the PREVENT risk category, 79 patients (46.2%) were in the low-risk category, 32 (18.7%) were in the borderline-risk category, and 51 (29.8%) were in the intermediate-risk category. In contrast, the SCORE2 systems placed 32 patients (28.3%) in the low- to moderate-risk categories. Only 9 patients (5.3%) were classified as being at high risk by PREVENT, while SCORE2 categorized 39 patients (34.5%) as being at high risk and 42 patients (37.2%) as being at very high risk. There was a strong correlation between the scores (r = 85, p < 0.001), with a Bland-Altman plot analysis showing a bias of -3.71 points and the limits of agreement ranging from -16.06 to 8.64. The total CAC score and CAD grading were significantly different across the PREVENT risk groups (p < 0.001 for all) but were similar across the SCORE2 groups (p = 0.3 and p = 0.051, respectively). Conclusions: There is a strong correlation and agreement between the two risk scores. However, SCORE2 tends to categorize more patients as high-risk than PREVENT does. Additionally, the PREVENT risk categories are more effective than SCORE2 in determining the likelihood of CAD based on CT results.
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    Article
    Citation - WoS: 2
    Citation - Scopus: 2
    Does Arterial Stiffness Predict Mortality in Patients With Scleroderma: a Long-Term Follow-Up Study
    (Verduci Editore s.r.l, 2023) Çolak, A.; Özpelit, Mehmet Emre; Birlik, M.; Özpelit, E.
    OBJECTIVE: Subclinical macrovascular impairment, which has been evaluated with various arterial stiffness (AS) parameters, has been defined in patients with systemic sclerosis (SSc). However, studies investigating the relationship between AS and clinical endpoints in SSc are lacking. This study aims to determine the prognostic value of AS parameters to predict all-cause mortality in SSc patients. PATIENTS AND METHODS: AS parameters [carotid-radial pulse wave velocity (PWV) and augmentation index (AIx)] were assessed via applanation tonometry. The prognostic value of these parameters was quantified in patients with SSc (n=60) without pulmonary arterial hypertension (PAH) and obvious cardiac involvement against survival. RESULTS: The overall median follow-up time was 10.3 years, and a 29.4% (n=20) mortality was observed. Four significant predictors of mortality were observed: lung involvement (HR 2.608, p=0.04), the lower level of predicted carbon monoxide diffusing capacity (HR 0.978, p=0.03), lower level of estimated glomerular filtration rate (HR 0.979, p=0.04), and elevated serum C reactive protein (CRP) levels (HR 1.066, p<0.001). Among these variables, elevated CRP was found to be an independent predictor of all-cause mortality. AS parameters were not associated with all-cause mortality (HR 1.014, p=0.6 for AIx and HR 0.737, p=0.19 for PWV, respectively). CONCLUSIONS: Long-term data failed to demonstrate the prognostic value of AS parameters in predicting all-cause mortality in SSc patients. The exact mechanisms of cardiovascular (CV) mortality in SSc patients deemed to be atherosclerotic in origin needs to be determined in large-scale studies. © 2023 Verduci Editore s.r.l. All rights reserved.
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    Article
    Cardiac Functions and Peripheral Arterial Stiffness in Patients With Polycystic Ovary Syndrome: a Cross-Sectional Study
    (Galenos Publ House, 2023) Colak, Ayse; Ozpelit, Mehmet Emre; Okyay, Emre; Kumral, Zeynep; Özpelit, Ebru
    BACKGROUND/AIMS: Polycystic ovary syndrome (PCOS) patients have been described as having subclinical cardiac and vascular damage; nevertheless, research data is contradictory. We aimed to assess global cardiac functions, peripheral arterial stiffness (AS), and the relationships between echocardiographic and AS measurements in patients with PCOS. MATERIALS AND METHODS: We enrolled 42 consecutive PCOS patients and 32 age- and body mass index (BMI)-matched healthy controls. All participants underwent a comprehensive two-dimensional echocardiographic examination. Applanation tonometry was utilized to determine peripheral AS [carotid-radial pulse wave velocity (PWV) and augmentation index (AIx)] in each participant. In addition, we evaluated the correlation between AS and echocardiographic parameters. RESULTS: The PCOS and control groups had similar ages and BMIs. Right ventricular (RV) and left ventricular (LV) diameters, LV mass, and LV ejection fraction were similar between the groups. Considering the pulse wave and tissue Doppler parameters of the cardiac functions, the LV septal S’, LV Tei index, RV S’, RV Tei index, and E/E’ ratio were comparable between the two groups. Peripheral AS parameters including, PWV and AIx were higher in those patients with PCOS [19.3±12.5 vs. 12.5±9.6; p=0.01 and 5 (4.7-5.5) vs. 4.4 (4.2-4.8); p=0.0001, respectively]. AS parameters were not correlated with echocardiographic parameters. CONCLUSION: Despite normal echocardiographic LV and RV functions, women with PCOS had increased AS. There was no correlation between echocardiographic and AS parameters in these patients.