Keskin, Zalike

Profile Picture
Profile URL
https://hdl.handle.net/20.500.14365/7446
Name Variants
Job Title
Email Address
zalike.keskin@ieu.edu.tr
Main Affiliation
05.02. Biomedical Engineering
Status
Former Staff
Website
ORCID ID
https://orcid.org/0000-0001-6789-6954
Scopus Author ID
57193538768
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
J-5320-2019

Sustainable Development Goals

NO POVERTY1
NO POVERTY
0
Research Products
ZERO HUNGER2
ZERO HUNGER
0
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GOOD HEALTH AND WELL-BEING3
GOOD HEALTH AND WELL-BEING
1
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QUALITY EDUCATION4
QUALITY EDUCATION
0
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GENDER EQUALITY5
GENDER EQUALITY
0
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CLEAN WATER AND SANITATION6
CLEAN WATER AND SANITATION
0
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AFFORDABLE AND CLEAN ENERGY7
AFFORDABLE AND CLEAN ENERGY
0
Research Products
DECENT WORK AND ECONOMIC GROWTH8
DECENT WORK AND ECONOMIC GROWTH
0
Research Products
INDUSTRY, INNOVATION AND INFRASTRUCTURE9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
0
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REDUCED INEQUALITIES10
REDUCED INEQUALITIES
0
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SUSTAINABLE CITIES AND COMMUNITIES11
SUSTAINABLE CITIES AND COMMUNITIES
1
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RESPONSIBLE CONSUMPTION AND PRODUCTION12
RESPONSIBLE CONSUMPTION AND PRODUCTION
0
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CLIMATE ACTION13
CLIMATE ACTION
0
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LIFE BELOW WATER14
LIFE BELOW WATER
0
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LIFE ON LAND15
LIFE ON LAND
0
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PEACE, JUSTICE AND STRONG INSTITUTIONS16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
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PARTNERSHIPS FOR THE GOALS17
PARTNERSHIPS FOR THE GOALS
0
Research Products
Documents

15

Citations

336

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10

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Documents

19

Citations

323

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Scholarly Output

2

Articles

2

Views / Downloads

1/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

91

Scopus Citation Count

106

Patents

0

Projects

0

WoS Citations per Publication

45.50

Scopus Citations per Publication

53.00

Open Access Source

0

Supervised Theses

0

JournalCount
Journal of Materıals Scıence1
Materıals Scıence And Engıneerıng C-Materıals For Bıologıcal Applıcatıons1
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  • Thumbnail Image
    Article
    Citation - WoS: 24
    Citation - Scopus: 27
    Crosslinking of Poly(vinyl Alcohol) Nanofibres With Polycarboxylic Acids: Biocompatibility With Human Skin Keratinocyte Cells
    (Springer, 2017) Cay, Ahmet; Kumbasar, E. Perrin Akcakoca; Keskin, Zalike; Akduman, Cigdem; Urkmez, Aylin Sendemir
    In this study, poly(vinyl alcohol) nanofibres were produced and evaluated for wound dressing applications. However, the solubility of the poly(vinyl alcohol) matrix in the aqueous medium generally limits its applications. To overcome this problem, 1,2,3,4 butanetetracarboxylic acid (BTCA) and citric acid (CA) were used as crosslinking agents. Successful bead-free nanofibres were produced, and they both preserved their fibrous structure after water treatment. The mean fibre diameters of polycarboxylic acid crosslinked nanofibres were lower compared to pure PVA nanofibres. Although the morphology of BTCA and CA crosslinked nanofibres was similar, the swelling degree of PVA/CA was found to be higher. Furthermore, toxicity and keratinocyte cell proliferation performance of produced PVA/BTCA and PVA/CA nanofibres indicated that these nanofibrous materials could be used in wound dressing applications.
  • Thumbnail Image
    Article
    Citation - WoS: 67
    Citation - Scopus: 79
    Novel Keratin Modified Bacterial Cellulose Nanocomposite Production and Characterization for Skin Tissue Engineering
    (Elsevier, 2017) Keskin, Zalike; Urkmez, Aylin Sendemir; Hames, E. Esin
    As it is known that bacterial cellulose (BC) is a biocompatible and natural biopolymer due to which it has a large set of biomedical applications. But still it lacks some desired properties, which limits its uses in many other applications. Therefore, the properties of BC need to be boosted up to an acceptable level. Here in this study for the first time, a new natural nanocomposite was produced by the incorporating keratin (isolated from human hair) to the BC (produced by Acetobacter xylinum) to enhance dermal fibroblast cells' attachment. Two different approaches were used in BC based nanocomposite production: in situ and post modifications. BC/keratin nanocomposites were characterized using SEM, FTIR, EDX, XRD, DSC and XPS analyses. Both production methods have yielded successful results for production of BC based nanocomposite-containing keratin. In vitro cell culture experiments performed with human skin keratinocytes and human skin fibroblast cells indicate the potential of the novel BC/keratin nanocomposites for use in skin tissue engineering. (C) 2017 Elsevier B.V. All rights reserved.