Crosslinking of Poly(vinyl Alcohol) Nanofibres With Polycarboxylic Acids: Biocompatibility With Human Skin Keratinocyte Cells
| dc.contributor.author | Cay, Ahmet | |
| dc.contributor.author | Kumbasar, E. Perrin Akcakoca | |
| dc.contributor.author | Keskin, Zalike | |
| dc.contributor.author | Akduman, Cigdem | |
| dc.contributor.author | Urkmez, Aylin Sendemir | |
| dc.date.accessioned | 2023-06-16T12:47:58Z | |
| dc.date.available | 2023-06-16T12:47:58Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | In this study, poly(vinyl alcohol) nanofibres were produced and evaluated for wound dressing applications. However, the solubility of the poly(vinyl alcohol) matrix in the aqueous medium generally limits its applications. To overcome this problem, 1,2,3,4 butanetetracarboxylic acid (BTCA) and citric acid (CA) were used as crosslinking agents. Successful bead-free nanofibres were produced, and they both preserved their fibrous structure after water treatment. The mean fibre diameters of polycarboxylic acid crosslinked nanofibres were lower compared to pure PVA nanofibres. Although the morphology of BTCA and CA crosslinked nanofibres was similar, the swelling degree of PVA/CA was found to be higher. Furthermore, toxicity and keratinocyte cell proliferation performance of produced PVA/BTCA and PVA/CA nanofibres indicated that these nanofibrous materials could be used in wound dressing applications. | en_US |
| dc.description.sponsorship | Research Foundation of Ege University [13-TKUAM-002] | en_US |
| dc.description.sponsorship | The authors acknowledge the Research Foundation of Ege University for the financial support given to this study (project number: 13-TKUAM-002). | en_US |
| dc.identifier.doi | 10.1007/s10853-017-1370-5 | |
| dc.identifier.issn | 0022-2461 | |
| dc.identifier.issn | 1573-4803 | |
| dc.identifier.scopus | 2-s2.0-85023754147 | |
| dc.identifier.uri | https://doi.org/10.1007/s10853-017-1370-5 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14365/920 | |
| dc.language.iso | en | en_US |
| dc.publisher | Springer | en_US |
| dc.relation.ispartof | Journal of Materıals Scıence | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Bacterial Cellulose Nanocomposite | en_US |
| dc.subject | 1,2,3,4-Butanetetracarboxylic Acid | en_US |
| dc.subject | Biomedical Applications | en_US |
| dc.subject | Citric-Acid | en_US |
| dc.subject | Cotton | en_US |
| dc.subject | Hydrogels | en_US |
| dc.subject | Glutaraldehyde | en_US |
| dc.subject | Stabilization | en_US |
| dc.subject | Cyclodextrin | en_US |
| dc.subject | Membranes | en_US |
| dc.title | Crosslinking of Poly(vinyl Alcohol) Nanofibres With Polycarboxylic Acids: Biocompatibility With Human Skin Keratinocyte Cells | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | Sendemir, Aylin/0000-0003-1818-6651 | |
| gdc.author.id | KUMBASAR, E. PERRIN AKCAKOCA/0000-0001-5295-9131 | |
| gdc.author.id | Çay, Ahmet/0000-0002-5370-1463 | |
| gdc.author.id | Akduman, Cigdem/0000-0002-6379-6697 | |
| gdc.author.id | Erdogan, Zalike Keskin/0000-0001-6789-6954 | |
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| gdc.author.scopusid | 8394019800 | |
| gdc.author.wosid | Sendemir, Aylin/A-6347-2014 | |
| gdc.author.wosid | KUMBASAR, E. PERRIN AKCAKOCA/B-3047-2018 | |
| gdc.author.wosid | Akduman, Cigdem/A-7584-2014 | |
| gdc.author.wosid | Çay, Ahmet/ABI-5118-2020 | |
| gdc.author.wosid | Erdogan, Zalike Keskin/J-5320-2019 | |
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| gdc.coar.type | text::journal::journal article | |
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| gdc.description.department | İzmir Ekonomi Üniversitesi | en_US |
| gdc.description.departmenttemp | [Cay, Ahmet; Kumbasar, E. Perrin Akcakoca] Ege Univ, Fac Engn, Dept Text Engn, TR-35100 Izmir, Turkey; [Keskin, Zalike] Izmir Univ Econ, Dept Biomed Engn, TR-35330 Izmir, Turkey; [Akduman, Cigdem] Pamukkale Univ, Denizli Vocat Sch Tech Sci, Dept Text Technol, TR-20100 Denizli, Turkey; [Urkmez, Aylin Sendemir] Ege Univ, Fac Engn, Dept Bioengn, Izmir, Turkey | en_US |
| gdc.description.endpage | 12108 | en_US |
| gdc.description.issue | 20 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q1 | |
| gdc.description.startpage | 12098 | en_US |
| gdc.description.volume | 52 | en_US |
| gdc.description.wosquality | Q2 | |
| gdc.identifier.openalex | W2734907445 | |
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| gdc.oaire.keywords | Fibrous structures | |
| gdc.oaire.keywords | Fibre diameters | |
| gdc.oaire.keywords | Nanofibers | |
| gdc.oaire.keywords | 540 | |
| gdc.oaire.keywords | 620 | |
| gdc.oaire.keywords | Produced Water | |
| gdc.oaire.keywords | Cross linking agents | |
| gdc.oaire.keywords | Wound dressings | |
| gdc.oaire.keywords | Swelling degree | |
| gdc.oaire.keywords | Biocompatibility | |
| gdc.oaire.keywords | Water treatment | |
| gdc.oaire.keywords | Polyvinyl alcohols | |
| gdc.oaire.keywords | Cell proliferation | |
| gdc.oaire.keywords | Aqueous medium | |
| gdc.oaire.keywords | Polycarboxylic acids | |
| gdc.oaire.keywords | Butanetetracarboxylic acid | |
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| gdc.oaire.sciencefields | 0210 nano-technology | |
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| gdc.virtual.author | Keskin, Zalike | |
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