The Relationship Between Daily Carbonhydrate and Fat Intake a Long With Migraine

Abstract

The pathophysiology of migraine is not fully understood. The trigeminovascular pathway activation, cortical spreading depression, vascular dysfunction, pro-inflammatory and oxidative states, and gut microbiota are investigated. In this study, we aimed to evaluate the relationship between diet and migraine disease characteristics of our patients. This study was conducted with episodic migraine without aura (n:30) and chronic migraine patients (n:30). Demographic data, body mass indexes (BMI), migraine characteristics were recorded from headache diaries. Food consumption were noted Daily from diet diaries. Total calorie intake and carbohydrate and fat amounts were calculated with an internet-based calorie calculator program.The mean age was 40.1±7.83 years in chronic migraine group ( group 1), and 39.1±6.09 years in group 2. The mean BMI of group 1 was significantly higher (respectively; 28.3±3.14, and 24.9±3.29). The mean duration of migraine was found longer in group 1. The mean headache attack duration was 29.9±21.85 hours in group 1, and 29.6±22.4 was in episodic migraine without aura group (group 2). There was no significant difference between both groups in terms of headache attack duration. Average Daily carbohydrate intake is 178.53±44.86 grams in group 1, and 171.42±50.67 grams in group 2. The mean Daily fat intake was 58.01±13.65 grams in group 1 and 56.62±7.51 grams in group 2. No significant difference was found between the groups in terms of Daily calorie, mean Daily fat and, average carbohydrate intake. In our study, we did not find difference in food intake between groups, but BMI of the chronic migraine group were higher. The role of diet on the migraine pathophysiology is still under investigation. An integrative approach to migraine patients by reviewing their diet will help to understand the pathophysiology of migraine, increase the quality of life of patients and prevent unnecessary drug usage.