Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.14365/5548
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Uysal, Hasan Armağan | - |
dc.contributor.author | Hunerli, Duygu | - |
dc.contributor.author | Çakmur, Raif | - |
dc.contributor.author | Dönmez Çolakoğlu, Beril | - |
dc.contributor.author | Ada, Emel | - |
dc.contributor.author | Yener, Görsev | - |
dc.date.accessioned | 2024-10-25T15:17:40Z | - |
dc.date.available | 2024-10-25T15:17:40Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 1300-0144 | - |
dc.identifier.issn | 1303-6165 | - |
dc.identifier.uri | https://doi.org/10.55730/1300-0144.5838 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.14365/5548 | - |
dc.description.abstract | Background/aim: In this study, besides the evaluation of gray and white matter changes in cognitively normal Parkinson's disease (PDCN) patients with volumetric magnetic resonance imaging (MRI) parameters, it was tried to show that some neuropsychological tests may be impaired in PD-CN patients. Materials and methods: Twenty-six PD-CN patients and 26 healthy elderly (HC) participants were included in the current study. Global cognitive status was assessed using the mini-mental state examination (MMSE), and the Montreal cognitive assessment scale (MoCA). Attention and executive functions were evaluated using the Wechsler memory scale-revised (WMS-R) digit span test and trail making test (TMT) part A and part B, the Stroop test, semantic and phonemic fluency tests, and clock drawing test. Magnetic resonance imaging (MRI) was acquired according to the Alzheimer's disease neuroimaging initiative (ADNI) protocol. Results: There were no significant differences among groups regarding age, sex, handedness, and years of education. In the comparison of the PD-CN group and the HC group, there was a statistical decrease in the total animal scores, lexical fluency, TMT part A and TMT part B scores in the PD-CN group. Subcortical gray matter volumes (GMV) were significantly lower in PD-CN patients. The PD-CN group had a significantly reduced total volume of right putamen and left angular gyrus compared to that in the HC group. We observed that putamen and angular gyrus volumes were lower in PD-CN patients. On the other hand, TMT part B may be a useful pretest in detecting the conversion of mild cognitive impairment in PD. Conclusion: Significant MRI volumetric measurements and neuropsychological test batteries can be helpful in the clinical follow-up in PD-CN patients. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Tubitak Scientific & Technological Research Council Turkey | en_US |
dc.relation.ispartof | Turkish journal of medical sciences | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Parkinson's disease | en_US |
dc.subject | volumetric MRI | en_US |
dc.subject | cognitive function | en_US |
dc.subject | Wechsler memory scale-revised | en_US |
dc.subject | trail making test | en_US |
dc.subject | Mini-Mental-State | en_US |
dc.subject | Gray-Matter | en_US |
dc.subject | Diagnostic-Criteria | en_US |
dc.subject | Impairment | en_US |
dc.subject | Dementia | en_US |
dc.subject | Mmse | en_US |
dc.subject | Atrophy | en_US |
dc.subject | Putamen | en_US |
dc.subject | Moca | en_US |
dc.subject | Screen | en_US |
dc.title | Can volumetric magnetic resonance imaging evaluations be helpful in the follow-up of cognitive functions in cognitively normal Parkinson's disease patients? | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.55730/1300-0144.5838 | - |
dc.identifier.pmid | 39295615 | en_US |
dc.identifier.scopus | 2-s2.0-85203673580 | en_US |
dc.department | İzmir Ekonomi Üniversitesi | en_US |
dc.authorwosid | ada, emel/AAC-3966-2020 | - |
dc.authorwosid | Uysal, Hasan Armağan/ISS-2315-2023 | - |
dc.authorscopusid | 57196036508 | - |
dc.authorscopusid | 59234573100 | - |
dc.authorscopusid | 6701745542 | - |
dc.authorscopusid | 59323716700 | - |
dc.authorscopusid | 6603810790 | - |
dc.authorscopusid | 7003804891 | - |
dc.identifier.volume | 54 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.wos | WOS:001308289100010 | en_US |
dc.institutionauthor | … | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 09.02. Internal Sciences | - |
crisitem.author.dept | 09.03. Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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