TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/4
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Article Turkish Thoracic Society Declaration on Peace and Health the Importance of Breathing in a World Without Ware(Galenos Publ House, 2026-01-30) Cetinkaya, Pelin Duru; Toreyin, Zehra Nur; Ozdemir, Hande Yuce; Yasin, Yesim; Kilinc, Oguz; Yorgancioglu, Arzu; Begic, Erencan; Bingöl, Züleyha; Erencan, Begiç; Kaya, Aslıhan Gürün; Demirdöğen, EzgiWar legitimizes the right to kill for its participants, equating victory with moral justification, however, this perceived legitimacy is largely Constructed on the deaths of civilians and other living beings. Medicine, by its very nature, is grounded in the principles of preserving ife, doing no harm, and adhering to scientific and ethical standards, and is therefore fundamentally opposed to the philosophy of war. Wars lead, directly and indirectly, to desaths, disability, displacement, poverty, and long-term public health disasters. Attacks on health Facilities, restrictions on access to food and water, environmental destruction, and air pollution disproportionately affect vulnerable Dopulations, particularly women and children. The psychological consequences of war often evolve into persistent neuropsychiatric conditions, including post-traumatic stress disorder, depression, and moral injury. Peace is not merely the absence of war, it is a prerequisite for health, environmental sustainability, and social well-being. The concept of positive peace strengthens health indicators hrough well-functioning institutions, equitable resource distribution, and the protection of human rights. Within this framework, health professionals and civil society organizations are critical actors in advocating for peace and in making human rights violations visible The Turkish Thoracic Society regards peace as an indispensable condition for public and respiratory health, affirms its opposition to all wars particularly the ongoing atrocities in Gaza-and reaffirms its commitment to sustained, health-based advocacy for peace,Letter The Necessity of Bronchiectasis Registries - The Turkish Registry of Bronchiectasis(Galenos Publ House, 2026-01-20) Kizilirmak, Deniz; Martinez-Garcia, Miguel Angel; Cicek, Sedat; Coskun, Aysin Sakar; Kilinc, Oguz; Edis, Ebru CakirBronchiectasis demonstrates a significant discrepancy between its high prevalence and the limited evidence base. Patient registries, both national and international, are key to collecting comprehensive data. However, the cost-effectiveness of this approach remains a subject of ongoing debate.1 In the opinion of the authors of this editorial, despite the significant costs and effort involved in establishing such registries, they are justified—provided that certain key characteristics are met. The registry must be sufficiently comprehensive in capturing relevant variables to avoid missing critical data that could impede meaningful research, particularly in areas such as therapeutic interventions, comorbidities, microbiological findings, and prognostic factors.Article The Turkish Version of Hydration Risk Assessment Tool in Older Patients: Cross-Cultural Adaptation and Psychometric Evaluation(Galenos Publishing House, 2025-08-28) Söylemez, Burcu Akpınar; Akyol, Merve Aliye; Küçükgüçlü, Özlem; Atasoy, EzgiObjective: Dehydration is a common and serious issue among older adults, with significant implications for their health and well-being. Preventing dehydration in older adults requires a multifaceted approach that involves early identification of risk factors, accurate detection methods, targeted interventions, and ongoing monitoring to ensure adequate hydration. For this reason, the study was designed to assess the validity and reliability of the Turkish adaptation of the Northumbria Assessment of Hydration (T-NoAH) among older patients. Materials and Methods: A methodological and descriptive approach was utilized in this investigation. After establishing linguistic validity, the study was conducted with a convenience sample of 360 older patients within 24 hours of admission to the hospital, using a descriptive information form and T-NoAH for data collection. The analyses performed included exploratory factor analysis, confirmatory factor analysis (CFA), discriminant validity assessment, internal consistency evaluation via Cronbach’s alpha, item-total correlation analysis, examination of ceiling and floor effects, and Hotelling’s T-squared test. Predictive accuracy was examined in the sample using a receiver operating characteristic curve, with serum osmolality as the reference test. Results: The tool had sufficient linguistic validity. The instrument consisting of 8 items and one factor was identified. This factor explained 39.24% of the total variance. Model fit indices were ≥0.90, as per CFA. Cronbach’s alpha was determined to be 0.73. There was no response bias identified, and there were no floor or ceiling effects. The optimal cut-off point (5 or more) showed sensitivity (70%) and specificity (89%) (area under the curve =0.795, 95% confidence interval, p<0.001) compared to non-dehydration group. Conclusion: This tool is a short, easily understandable and applicable measurement for assessing older patients’ hydration risk. It can be used by nurses to evaluate the risk of dehydration in older patients and to implement and evaluate effective interventions according to risk situations.Article Impact of Inspiratory Muscle Strength and Lung Function on Functional Exercise Capacity in Post-Myocardial Infarction Patients: A Cross-Sectional Study(Galenos Publishing House, 2025-09-18) Aktan, Rıdvan; Ozalevli, Sevgi; Dursun, Huseyin; Aktan, Özge Ocaker; Ocaker Aktan, OzgeOBJECTIVE: This study aims to investigate the contribution of lung function and respiratory muscle strength in predicting functional exercise capacity in post-myocardial infarction (MI) subjects. MATERIAL AND METHODS: This cross-sectional study included 56 stable post-MI subjects. Lung function was assessed using a digital spirometer, and respiratory muscle strength was measured using an intraoral pressure meter. The 6-minute walk distance (6MWD) was conducted to assess functional exercise capacity. Correlations and multiple regression analyses were performed to evaluate predictors of 6MWD, considering demographic factors, lung function, and respiratory muscle strength. The Bland-Altman plot was used to investigate the agreement between observed and predicted 6MWDs. RESULTS: Significant positive correlations were found between 6MWD and forced vital capacity (FVC)%predicted (r = 0.528, P = 0.022) and maximum inspiratory pressure (MIP)%predicted (r = 0.640, P = 0.022). Age (r = -0.350, P = 0.008) and body mass index (BMI) (r= -0.561, P < 0.001) were negatively correlated with 6MWD. The best regression model included MIP%predicted (β = 0.332, P = 0.002), BMI (β = -0.264, P = 0.012), being male (β = 0.262, P = 0.003), age (β = -0.210, P = 0.020), and FVC%predicted (β = 0.219, P = 0.026) as significant unique contributors. The final multiple linear regression model was significant [F (5, 50) = 19.08, P < 0.001] and explained 65.6% of the variance (R2 = 0.656) in the 6MWD. CONCLUSION: Lung function and respiratory muscle strength significantly contribute to functional exercise capacity in post-MI. This study emphasizes the importance of comprehensive respiratory function assessments in rehabilitation strategies to improve exercise capacity in patients with post-MI.Article HR-LCMS Based Metabolite Profiling of Methanolic Leaf Extract of Terminalia Pallida Brandis and Its Antioxidant Potential(2025-04-08) Guguloth, Dr. Sarvan KumarTerminalia species are being reported as medicinally useful. Terminalia pallida Brandis is one of the plants of the family Combretaceae. The aim of the present study is to catalog the phytochemical distribution and to validate the antioxidant potential of methanolic leaf extract (METP). Antioxidant potential of methanolic leaf extract was estimated by DPPH assay and phytochemical distribution was assessed by HR-LCMS analysis. The antioxidant test result of leaf extract displayed a potential free radical scavenging effect at test concentrations (p<0.001). In HR-LC-MS study a total of 29 bioactive compounds of a variety of chemical classes like flavanoids, alkaloids, fatty acids, diterpenoids, glycosides, amino acids and polyphenols etc were identified in both positive & negative ion mode, and among these few compounds possessed various biological activities. Based on these obtained results, it is concluded that METP constitute 29 bioactive compounds and possess potential antioxidant property in concentration dependent manner.Article Self-Reported Urinary Incontinence Prevalence in Women with Versus Without Regular Structured Exercise: A Cross-Sectional Study(Dokuz Eylül University Institute of Health Sciences, 2025-09-30) Goksuluk, Merve Basol; Yeşilyurt, Seda Yakıt; Olgun, Başak; Civelek, Buket; Erak, İlknur; Gürbüzer, EzgiPurpose: The aim of this study was to compare urinary incontinence (UI) between women with and without regular structured exercise habits. Material and Methods: A total of 184 women, including 92 with regular and structured exercise habits and 92 without, were included in this study conducted between May and December 2024. Reported UI (Global Pelvic Floor Bother Questionnaire), symptoms, and impact on quality of life (Incontinence Severity Index, International Consultation on Incontinence Questionnaire-Short Form) were assessed in all women. This study was conducted following the STROBE guidelines. Results: The prevalence of stress urinary incontinence (SUI), a subtype of UI, was significantly higher in women without structured exercise habits (p=0.018). The average duration of exercise among women with regular exercise habits was 24 months (range 6–240), and 85% practiced Pilates. In addition, women with structured exercise habits had higher education levels (p<0.001), and a large proportion were employed as civil servants and retirees (p<0.001 and p=0.002, respectively). Conclusion: Women who engage in regular and structured exercise have a lower prevalence of SUI. Women with exercise habits tend to have higher education and socioeconomic levels, and the impact of incontinence on quality of life is less severe.Article Return Transmission Among Fossil Energy Commodities, Clean Energy Stocks, Green Bonds, and Energy Cryptocurrency(Mehmet Akif Ersoy University, 2025-09-30) Cagli, Efe C.; Mandacı, Pınar Evrim; Kocakaya, Birce Tedik; Tedik Kocakaya, Birce; Evrim Mandaci, PinarThis paper investigates return transmission among fossil energy commodities (crude oil, natural gas, gas oil, unleaded gasoline, and heating oil), clean energy stocks, green bonds, and energy cryptocurrency markets. We consider Bloomberg’s fossil energy subindices to proxy various energy commodities. We use the WilderHill Clean Energy Index (ECO) and Solactive Green Bond Index (GB) as proxies for clean energy stocks and green bonds. In addition, the Powerledger (POWR) coin is used to proxy energy cryptocurrency. We employ the TVP-VAR frequency connectedness technique for the period from November 12, 2017, to September 28, 2023. Our findings indicate a moderate level of interdependence with an apparent increase observed during the COVID-19 pandemic. Notably, short-term factors play a significant role in shaping this connectedness. Furthermore, the analysis identifies clean energy stocks, green bonds and energy cryptocurrencies as recipients, while all fossil energy commodities other than natural gas and gasoline are identified as transmitters. These conclusions have important implications for investors and policymakers.Letter Response to: Effectiveness of a Program to Raise Awareness About Pneumococcal Vaccination Among Physicians and Patients with Chronic Respiratory Diseases: A Multicenter Cohort Study(Galenos Publ House, 2025-06-03) Şimşek, Nurdan; Altın, Sedat; Sayiner, Abdullah; Yalnız, Enver; Karakurt, Zuhal; Kul, Seval; Uslu, Ozgur; Veske, Nurdan Simsek; Karakut, Zuhal; Oruc, OzlemArticle İnfluenza A/B Virüs ve RSV Validasyon Standartlarının Dijital PCR ile Kantitasyonu(Ankara Microbiology Soc, 2025-07-26) Sayıner, Ayca Arzu; Bulgurcu, AlıhanMikrobiyolojik tanı laboratuvarlarında kullanılacak tanı testleri için kantitatif standartların kullanıldığı yöntem doğrulama (verification) veya geçerli kılma (validation) çalışmaları gereklidir. Nükleik asit testlerinde sentetik nükleik asit veya plazmit yerine tam virüs içeren standartların kullanılması; ekstraksiyon, revers transkripsiyon ve amplifikasyonu içerecek şekilde tanı testinin tüm basamaklarının gerçek yaşam koşullarında değerlendirilmesini sağlar. Solunum yolu virüsleri için nükleik asit testlerine yönelik ticari kantitatif standart materyaller sınırlıdır. Bu çalışmada; influenza A virüs (infA), influenza B virüs (infB) ve respiratuvar sinsityal virüs (RSV) için dijital polimeraz zincir reaksiyonu [digital polymerase chain reaction (dPCR)] kullanılarak, kantitatif nükleik asit standartları geliştirilmesi amaçlanmıştır. Çalışmada; RSV, infA, infB RNA pozitif olduğu bilinen nazofarengeal sürüntü örneklerinin havuzlanmasıyla hazırlanan örneklerdeki viral nükleik asit miktarı, ticari primer/prob setleri (Qiagen, Almanya) kullanılarak dPCR (QIAcuity, Qiagen) yöntemiyle belirlenmiştir. Nükleik asit ekstraksiyonu, ticari bir kit (Xi’an Tianlong Science&Technology Co, Çin) kullanılarak yapılmıştır. dPCR yönteminin infA, infB ve RSV için analitik duyarlılık (LoD) ve kantitasyon alt sınırı (LoQ), çalışma içi ve çalışmalar arası tekrarlanabilirliği ve doğrusallığı belirlenmiştir. dPCR ile çalışılan örnekler, kantitatif revers transkripsiyon gerçek zamanlı [quantitative reverse transcription realtime (qrRT)] PCR (qRT-PCR) ile de çalışılarak Ct değerleri belirlenmiştir. Ct değerleri ile dPCR-kantitasyon sonuçları arasındaki ilişki lineer regresyon ile değerlendirilmiştir. İstatistiksel analiz GraphPad Prism 10.4.0 (GraphPad, ABD) ve Excel Analysis ToolPak kullanılarak yapılmıştır. İnfA, infB ve RSV için dPCR yönteminin LoD değerleri sırasıyla 93.75, 15.59 ve 26.23 kopya/mL olarak belirlenmiştir. dPCR yönteminin çalışma içi tekrarlanabilirliği (varyasyon katsayısı, %CV), düşük viral yükü olan örneklerde daha yüksek olmak üzere 0.06-7.97 arası saptanmıştır. Çalışmalar arası tekrarlanabilirlik 0.73-5.41 olarak bulunmuştur. İnfA ve infB için 3-4 log10, RSV için 7 log10 aralığında dilüsyonlar ile yapılan doğrusallık analizinde her üç virüs için de r 2≥ 0.99 olarak bulunmuştur. dPCR ile ölçülen konsantrasyonların, qRT-PCR Ct sonuçları ile korele olduğu saptanmıştır. dPCR ile qRT-PCR testlerinin çalışma içi ve çalışmalar arası tekrarlanabilirlik sonuçları karşılaştırıldığında, dPCR’nin %CV değerinin anlamlı olarak daha düşük olduğu saptanmıştır (p= 0.0312). Çalışma sonuçları dPCR yönteminin, kantitatif nükleik asit standartları elde etmede tekrarlanabilirliği yüksek ve güvenilir bir yöntem olduğunu göstermiştir. Elde edilen kantitatif standartlar ile viral yük belirlemeye yönelik tanı yöntemleri geliştirmek ve/veya bu tür testlerin yöntem onayı analizlerini yapmak mümkündür. Sonuç olarak çalışmada, havuzlanmış hasta örnekleri kullanılarak dPCR yöntemiyle infA, infB ve RSV için güvenilir kantitatif nükleik asit standartlar elde edilmiş ve dPCR yönteminin performans analizleri gerçekleştirilmiştir. Bu çalışma, dPCR ile kantitatif viral nükleik asit standartlarının üretimine bir örnek olmuştur.Article Finansal Stresin Fosil Enerji Emtiaları ile Yeşil Enerji Piyasaları Arasındaki Dinamik Bağlantılılığa Etkisi(Economic and Financial Research Assoc – EFAD, 2025-06-30) Cagli, Efe C.; Mandacı, Pınar Evrim; Kocakaya, Birce Tedik; Taşkın, DilvinBu makale, FSI (Finansal Stres Endeksi), VIX (Volatilite Endeksi) ve EPU (Ekonomik Politika Belirsizliği) gibi seçili stres değişkenlerinin yeşil piyasalar (hisse senetleri ve tahviller) ile fosil enerji emtiaları arasındaki dinamik bağlantılılık üzerindeki etkilerini incelemeyi amaçlamaktadır. Bağlantılılığı ölçmek için TVP-VAR modelini ve bu stres değişkenlerinin 1 Kasım 2012'den 15 Kasım 2022'ye kadar bu bağlantı üzerindeki etkilerini araştırmak için Fourier Kümülatif Granger Nedensellik testini kullanıyoruz. Sonuçlar, esas olarak kısa vadeli dinamiklerden kaynaklanan orta düzeyde getiri bağlantılılığı olduğunu gösteriyor ve bu da çeşitlendirmenin uzun vadeli yatırımlar için daha faydalı olabileceğini gösteriyor. COVID-19 salgını sırasında yüksek bağlantılılık gözlemliyoruz. Bağlantılılık, su şirketi hisseleri hariç, fosil enerji emtiaları arasında yüksek ancak yeşil hisse senedi ve tahvil piyasaları arasında düşüktür. Su hisselerinin piyasalar üzerinde önemli bir etkisi vardır, bunu petrol takip eder. Nedensellik test sonuçlarımız, FSI ve VIX'in bunların arasındaki bağlantılılığı etkilediğini göstermektedir.