Vatansever, Safa
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Vatansevers, S.
Vatansever, S.
Vatansever, Safa
Vatansever, S.
Vatansever, Safa
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safa.vatansever@ieu.edu.tr
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09.04. Surgical Sciences
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Former Staff
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Sustainable Development Goals
Documents
12
Citations
97
h-index
5
Documents
12
Citations
84
Scholarly Output
10
Articles
7
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0/0
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0
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0
WoS Citation Count
13
Scopus Citation Count
10
WoS h-index
2
Scopus h-index
2
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0
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0
WoS Citations per Publication
1.30
Scopus Citations per Publication
1.00
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4
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0
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9 results
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Now showing 1 - 9 of 9
Conference Object Donor Complications Encountered Among Right Lobe Live Liver Donors(Lippincott Williams & Wilkins, 2024) Farajov, R.; Iakobadze, Z.; Vatansever, S.; Karaca, C.; Yilmaz, C.; Kilic, K.; Kilic, M.Conference Object Donor Complications Encountered Among Left Lateral Segment Live Donors(Lippincott Williams & Wilkins, 2024) Iakobadze, Z.; Vatansever, S.; Farajov, R.; Karaca, C.; Yilmaz, C.; Kilic, K.; Kilic, M.Article Citation - WoS: 8Citation - Scopus: 7The Expression of Forkhead Transcription Factors in Decidua and Placenta in Patients With Missed Abortion(I R O G Canada, Inc, 2015) Ozbilgin, K.; Kahraman, B.; Turan, A.; Atay, C.; Vatansever, S.; Inan, S.; Ozcakir, T.Background: Forkhead transcription factors 3a (FOXO3a) has pleiotropic biological functions in the female reproductive tract. FOXO3a has a function in decidualization, in placental development, and also in inhibition of apoptosis. This study aims to investigate a possible role of FOXO3a in missed abortion. Materials and Methods: Decidual and placental tissue samples were obtained from the women with unwanted pregnancy as the control group and with missed abortion as the patient group. Immunohistochemistry technique was utilized to compare FOXO3a expression of the decidual cells in uterine decidual stroma and cytotrophoblast-syncytiotrophoblast cells in placental villous stroma. Immunohistochemistry was evaluated semi-quantitatively utilizing the H-score technique. Results: It was demonstrated that H-Scores of FOXO3a expression in both uterine decidual stroma were increased in the missed abortion group (255.83 +/- 12.41) than in the normal pregnancy group (133.33 +/- 17.43). It was also shown that there was no difference between non-decidual area of the endometrium of the normal pregnancy and the missed abortion group (30.33 +/- 4.32; 39.66 +/- 14.30, respectively) and placental villous stroma (13.00 +/- 1.89; 13.00 +/- 1.67, respectively). However, the immunoreactivity of cytotrophoblast and syncytiotrophoblast cells significantly increased in the missed abortion group (18.83 +/- 1.47; 322.00 +/- 6.06, respectively) than in the normal pregnancy group (11.00 +/- 1.26; 254.00 +/- 8.17, respectively) (p < 0.05). Conclusion: These data support the hypothesis that increased FOXO3a expression in missed abortion may prevent the discharge of dead fetus to maintain decidualization, prevention of oxidative stress, immunomodulation, and inhibition of apoptosis.Article Laparoskopik Adrenalektomi Sonrası Hastanede Kalış Süresine Etkili Faktörler(2024) Üstün, Mehmet; Akpınar, Göksever; Tuncer, Korhan; Vatansever, SafaAmaç: Bu çalışmanın amacı laparoskopik adrenalektomi uygulanan hastalarda, ameliyat sonrasında hastanede kalış süresine etki eden faktörleri değerlendirmektir. Yöntem: 2012-2022 yılları arası laparoskopik adrenalektomi uygulanan hastalar retrospektif olarak incelendi. Hastanede kalış süresi için çalışma popülasyonunun 75. yüzdelik dilimi sınır olarak belirlendi. Bu süreden daha uzun süre kalınması uzamış hastanede kalış olarak tanımlandı. Uzamış hastanede kalışa etkili faktörler tek değişkenli ve çoklu lojistik regresyon analizleriyle incelendi. Tek değişkenli lojistik regresyon analizinde p-değeri <0,10 olan değişkenler çoklu regresyon modeline dahil edildi. Bulgular: Çalışmaya toplam 86 hasta dahil edildi. Hastaların 71’i (%83) kadındı. Ortanca yaş 54 (çeyrekler arası aralık, 45-61) yıldı. Ortanca hastanede kalış süresi 2 (interkuartil aralık, 2-2) gündü. Popülasyonun 75. yüzdelik dilimine göre 2 günden uzun süren kalış süresi uzamış hastanede kalış olarak belirlendi. Buna göre 14 (%16) hastada uzamış hastanede kalış saptandı. Çoklu regresyon analizi sonucunda operasyon süresi (olasılık oranı: 1,03; p-değeri: 0,017), açık cerrahiye geçiş (odds oranı: 4,79; p-değeri: 0,045) ve erkek cinsiyet (olasılık oranı: 5,61; p-değeri: 0,022), uzamış hastanede kalış süresi ile ilişkili bulundu. Sonuç: Laparoskopik adrenalektomi, bir çok adrenal patolojinin tedavisinde güvenilir bir yöntemdir. Operasyon süresi ve açık cerrahiye geçiş, uzamış hastanede kalış süresi ile ilişkili bulunmuştur; ancak kanıt düzeyi yüksek çalışmalara ihtiyaç vardır.Article Crigler-Najjar Sendromunda Karaciğer Nakli(2024) Abdullayeva, Madina; Vatansever, Safa; Kazimi, Mirjalal; Beydullayev, Kamran; Asadov, Kanan; Yusifli, Zarifa; Rasulzada, HajıCrigler-Najjar sendromu, unkonjüge hiperbilirubinemiye neden olan nadir, kalıtsal bir hastalıktır. Karaciğer nakli, Crigler-Najjar sendromu için kesin tedavi sağlayan bir seçenektir. Bu olgu sunumunda Crigler-Najjar sendromu nedeniyle karaciğer nakli yapılan iki hasta sunuldu. Gilbert sendromu olarak yanlış teşhis konulan ilk hasta 15 yaşında bir erkekti. Var olan konuşma ve yürüme bozukluğu karaciğer nakli sonrası kısmi olarak düzeldi. İkinci hasta 22 yaşında erkekti. Hastalığın hafif bir klinik formuna sahip olmasına rağmen, karaciğer fibrozisi gelişmişti. Karaciğer nakli her iki hastaya da önemli bir morbidite olmaksızın başarıyla uygulandı.Article Citation - WoS: 2Citation - Scopus: 1Prediction of Short-Term Results After Laparoscopic Right Hemicolectomy. Is Sarcopenia Superior To Other Methods?(Mexican acad surgery, 2024) Erözkan, Kamil; Vatansever, Safa; Tamam, Selim; Ünal, Ali E.Objective: We aimed to determine the factors that predict early mortality and morbidity in patients who underwent laparoscopic right hemicolectomy and their superiority over each other. Method: Demographic data, age -adjusted Charlson Comorbidity Index, American Society of Anesthesiologists Score, body mass index, modified -Glasgow Prognostic Score (mGPS), stage of disease, and sarcopenia were evaluated in patients who underwent right hemicolectomy between 2010-2022. Their superiority in predicting short-term outcomes was compared. Results: 78 patients were included in the study. The complication rate was higher in sarcopenic patients (p = 0.002). A high mGPS score was associated with increased mortality risk (p = 0.012). Other methods were not found to be related to short-term results. Conclusions: Sarcopenia is useful for the prediction of complications, and the mortality rate can be estimated by the mGPS score. These are superior to the other short-term results prediction methods. However, randomized controlled studies are needed.Article Citation - WoS: 3Citation - Scopus: 2A Comparison of the Molecular Distribution of Proangiogenic Factors in Endometrium of Missed Abortions and of Voluntary First Trimester Termination Cases(7847050 Canada Inc, 2015) Ozcakir, T.; Turan, M. A.; Simsek, F.; Atay, C.; Vatansevers, S.; Ozbilgin, K.Objective: The authors aimed to evaluate the angiogenic changes that occur in the cases with missed abortions compared with the voluntary termination of pregnancy as control group, with this controlled clinical study. Materials and Methods: The study included fifteen healthy volunteer women with unwanted pregnancy less than 10th gestational week in an academic research environment. The patients were 19 women between 6th and 11th gestational weeks diagnosed with missed abortion as the patient group. Immunohistochemistry was utilized to examine temporal and spatial expression of vascular endothelial growth factor (VEGF) and their two receptors: VEGF-Rl (Flt-1) and VEGF-R2 (Flk-1/KDR), and Trombospondin-1, eNOS, iNOS, and HIF-1 alpha in the both deciduas and placenta of the both groups. Results: This study discovered the significant difference (p < 0.005) between the groups of controlled and missed abortion in the decidual and placental cell components, and has put forward that thrombospondin and iNOS have an impact on abortion through antiangiogenic effect in cases of missed abortions. Conclusions: The potential role of molecules affecting angiogenesis in the etiology of missed abortion has been evaluated and the authors aimed for this to be a guide for studies on further treatments and on the prevention of the development of missed abortions.Article Evaluation of the Relationship Between Prognostic Nutritional Index and Early Clinical Outcomes in Intestinal Transplantation(Elsevier Inc., 2025) Akpinar, G.; Eyduran, B.; Vatansever, S.; Kocatürk, E.; Üstün, M.Background: Malnutrition in patients with intestinal insufficiency negatively affects the success of intestinal transplantation. In our research, we assessed patients' nutritional status using the PNI scale and examined the impact of the PNI score on clinical outcomes during the post-transplant phase. Results: The acute rejection rate was 38.1%, and the 30-day survival rate was 90.5%. Median PNI values were 41.5 (min-max: 33.5-65), 29.5 (min-max: 13.5-56.5), 33 (min-max: 3-51), 35.7 (min-max: 24.5-54), 33.5 (min-max: 24.5-75.5) preoperatively and on postoperative 1, 7, 15, and 30 days, respectively. No significant relationship was found between the other parameters and the PNI. Conclusions: The PNI score alone fails to adequately represent a patient's nutritional status and has not demonstrated effectiveness in predicting early-term outcomes for those undergoing intestinal transplantation. Additional studies involving a larger number of patients and diverse nutritional markers are necessary for further insights into this matter. © 2025 Elsevier B.V., All rights reserved.Article Laparoscopic Right Hemicolectomy: Comparison of Medial and Lateral Approach(2023) Ünal, Ali Ekrem; Vatansever, Safa; Erözkan, Kamil; Tamam, Selim; Benk, Mehmet Şah; Azılı, Cem; Bayar, SancarAim: We aimed to examine the early oncological and clinical outcomes of the medial and lateral approaches for right hemicolectomy. Materials and Methods: Laparoscopic right hemicolectomy patients who underwent medial and lateral approach techniques in our clinic between March 2010 and September 2022 were retrospectively reviewed. Demographic data of the patients, tumor, and operation characteristics, operation, clinical, pathological, mortality, and morbidity outcomes were recorded. Data were compared with the Chi-square test or Fisher Exact test according to the expected value for categorical variables. The Mann-Whitney U test was used because the data for continuous variables were not normally distributed. Results: In total, hundred and fourteen patients who underwent laparoscopic right colon resection were included. 47 patients were operated on with the medial approach, and 67 with the lateral approach. In terms of harvested lymph node number, operation time, estimated blood loss, first fluid intake, first solid intake, first flatus, blood transfusion history, length of stay, anastomotic leaks, and mortality were not significantly different between the two approaches (p>0.05). However, the number of positive lymph nodes was significantly higher in the medial approach (p=0.013). Conclusion: The medial and lateral approaches are feasible and effective techniques for right hemicolectomy. There is no difference between the short-term oncologic results. However, randomized controlled studies are needed for long-term results
