Güllüoğlu, Halil
Loading...
Profile URL
Name Variants
Gulluoglu, Halil
Gulluoglu, H.
Gulluoglu, H.
Job Title
Email Address
halil.gulluoglu@ieu.edu.tr
Main Affiliation
09.02. Internal Sciences
Status
Current Staff
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
Sustainable Development Goals
11
SUSTAINABLE CITIES AND COMMUNITIES
0
Research Products
4
QUALITY EDUCATION
0
Research Products
8
DECENT WORK AND ECONOMIC GROWTH
0
Research Products
12
RESPONSIBLE CONSUMPTION AND PRODUCTION
0
Research Products
9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
0
Research Products
15
LIFE ON LAND
0
Research Products
6
CLEAN WATER AND SANITATION
0
Research Products
1
NO POVERTY
0
Research Products
7
AFFORDABLE AND CLEAN ENERGY
0
Research Products
10
REDUCED INEQUALITIES
0
Research Products
14
LIFE BELOW WATER
0
Research Products
2
ZERO HUNGER
0
Research Products
13
CLIMATE ACTION
0
Research Products
5
GENDER EQUALITY
0
Research Products
16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
Research Products
17
PARTNERSHIPS FOR THE GOALS
0
Research Products
3
GOOD HEALTH AND WELL-BEING
1
Research Products
Documents
27
Citations
342
h-index
9
Documents
36
Citations
303
Scholarly Output
10
Articles
8
Views / Downloads
16/25
Supervised MSc Theses
0
Supervised PhD Theses
0
WoS Citation Count
9
Scopus Citation Count
7
WoS h-index
2
Scopus h-index
2
Patents
0
Projects
0
WoS Citations per Publication
0.90
Scopus Citations per Publication
0.70
Open Access Source
9
Supervised Theses
0
Google Analytics Visitor Traffic
| Journal | Count |
|---|---|
| Turkish Journal of Neurology | 2 |
| European Journal of Neurology | 1 |
| Journal of Clinical Medicine | 1 |
| Meandros Medical and Dental Journal | 1 |
| Medical Journal of Bakirkoy | 1 |
Current Page: 1 / 2
Scopus Quartile Distribution
Competency Cloud
10 results
Scholarly Output Search Results
Now showing 1 - 10 of 10
Article Citation - WoS: 1Citation - Scopus: 1Comparison of Facial Palsy Cases Before and During the Pandemic Coronavirus Disease-2019(Galenos Publ House, 2023) Uysal, Hasan Armağan; Güllüoğlu, HalilObjective: The pandemic coronavirus disease-2019 (COVID-19) is caused by a novel type of coronavirus named severe acute respiratory syndrome coronavirus-2 and is rapidly spreading all over the world. In addition to various neurological symptoms, acute facial palsy was diagnosed as the main neurological symptom in some COVID-19 patients. The current study aimed to analyze the variation and any possible association in the case numbers or medical symptoms of patients with facial palsy before and during the COVID-19 pandemic.Methods: The clinical files of patients who were diagnosed with facial palsy in the Neurology Department of Medicalpoint Hospital, University of Economics Faculty of Medicine, Izmir were retrospectively investigated. To compare the facial palsy cases according to different periods, two patient groups were formed: before the COVID-19 pandemic and during the COVID-19 pandemic. The pandemic group was further divided into two subgroups as COVID-19-positive and COVID-19-negative patients to compare the effects of COVID-19 on facial palsy.Results: During the specified COVID-19 period (May 2020-January 2021) of the study, 38 patients were admitted to the hospital for facial palsy; 34 facial palsy patients were admitted in the same calendar period as the two previous years (May 2018-January 2019). There was no significant difference in the frequency of facial palsy between these two time periods. There were significant differences between before and during the COVID-19 pandemic groups regarding response to cortisone therapy (p<0.001), facial palsy grade (p<0.001), electromyography findings (p=0.005), denervation (p<0.001), and 6 months recovery (p<0.001) data. There were also significant differences between the COVID-19-positive and COVID-19-negative subgroups regarding response to cortisone therapy (p=0.015) and facial palsy grade (p=0.001).Conclusion: The current study findings support the possible association between the severity of the clinical course of facial palsy and COVID-19. Further studies are needed to prove a direct association between facial palsy and COVID-19.Article Citation - WoS: 1Citation - Scopus: 2Contralateral Facial Innervation in Healthy Subjects and in Patients With Peripheral Facial Palsy(MDPI, 2024) Güllüoğlu, Halil; Uysal, Hasan Armağan; Uludağ, BurhanettinBackground: We aimed to investigate the extent of the response of the orbicularis oris muscle to stimulation of the contralateral facial nerve both in patients with peripheral facial palsy (PFP) and in healthy subjects. Methods: EMG was performed at 2-6 weeks after the onset of PFP in the patient group and at any time in the healthy control group. We performed nerve conduction testing, electroneurography, and surface and needle EMG. Results: A total of 276 participants (patients/healthy controls: 218/58) were analyzed. The extent of the response of the contralateral orbicularis oris muscles to facial nerve stimulation was higher in healthy controls compared to that in the affected group. The response of the contralateral orbicularis oris muscles to stimulation of the paralyzed facial nerve was more extensive in those patients to whom glucocorticoid or physical therapy had been given. Cross-facial innervation in the orbicularis oris muscle extended up to 1.5 cm in one-third of healthy controls and was higher than that in those with PFP. Glucocorticoid or physical therapy seemed to improve cross-innervation in facial palsy. Conclusions: Our findings suggest that the stimulus leading to the contralateral muscular response is mediated through crossing axons rather than muscular fibers.Conference Object Citation - WoS: 1Plasma Exchange in Neuroimmunologic Disorders(Wiley, 2022) Gulluoglu, H.; Uysal, H.[Abstract Not Available]Article Demansın Davranışsal ve Psikolojik Belirtileri Bilgi Ölçeği’nin Türkçe Versiyonunun (DDPB-T) Geçerliliği ve Güvenilirliği: Bakıcılar Arasında Psikometrik Bir Değerlendirme(Turkiye Sinir ve Ruh Sagligi dernegi, 2024) Var, Levent; Güllüoğlu, Halil; Uysal, Hasan Armağan; Poyraz, Turan; Başaran, Simay; Eşkut, NeslihanAmaçArticle Türk Erişkin Nöroloji Uzmanlarında Tükenmişlik(Galenos Publ House, 2023) Uysal, Hasan Armagan; Keskin, Ahmet Onur; Güllüoğlu, Halil; Yildiz, Fatma GokcemAmaç: Tıp doktorlarında tükenmişlik hasta bakımını veya klinisyenin fiziksel performansını kötü etkileyebilir. Çalışmamızda Türk nöroloji uzmanlarındaki tükenmişlik oranını ve tükenmişlikle ilişkili faktörleri araştırmayı amaçladık. Gereç ve Yöntem: Çalışmaya Türkiye’deki nöroloji uzmanları dahil edildi. Katılımcılardan çeşitli düşünce ve deneyimler ile ilişkili 33 sorudan oluşan bir anketi doldurmaları istendi. Katılımcılar sorulara şu şekilde cevap verdiler: Kesinlikle katılmıyorum, kısmen katılıyorum, katılıyorum, kuvvetle katılıyorum, kesinlikle katılıyorum. Sorunun anlamına göre (negatif veya pozitif), verilen cevap 1-5 arasında puanlandırıldı. Puanların toplamının maksimum (165) puana bölünmesiyle tükenmişlik oranı elde edildi. Bulgular: Ortalama yaş 38,78 (±8,42) yıl, kadın/erkek oranı 461/255 olarak bulundu. Ortalama tükenmişlik oranı %46,73 (±8,95) idi. Erkek cinsiyet, akademisyenlik, akademik derecenin yüksek olması, tıp fakültesi hastanesinde çalışmak, düşük maaş, bekar olmak, ebeveyn olmamak, nöbet tutmak, icapçı olmamak veya yoğun bakım ünitesinde çalışmak daha yüksek tükenmişlik oranı ile ilişkili bulundu. Tükenmişlik oranı, yaş, muayene edilen hasta sayısı ve çalışma saatleri ile pozitif, yardımcı sağlık personeli veya nörolog sayısı ile negatif korelasyon içindeydi. Sonuç: Bizim çalışmamız, Türk erişkin nöroloji uzmanlarından oluşan büyük bir örneklemde yüksek tükenmişlik oranını gösteren ilk çalışmadır. Erkek olmak, ileri yaş, akademisyen, profesör veya bekar olmak, ebeveyn olmamak, tıp fakültesi hastanesinde veya yoğun bakım ünitesinde çalışmak, düşük maaş, nöbet tutmak, yüksek hasta sayısı veya çalışma saati tükenmişlikle ilişkili görünmektedir.Article Citation - WoS: 2Differences in the Differential Expression of Micrornas Between Patients With Familial Multiple Sclerosis and Those With Sporadic Multiple Sclerosis(Galenos Publ House, 2023) Güllüoğlu, Halil; Uysal, Hasan Armağan; Poyraz, Turan; Altun, Zekiye; Kaya, Derya; Özcelik, Pınar; İdiman, Egemen; Poyraz, TuranObjective: Multiple sclerosis (MS) is a heterogeneous disease with clinical and immunological features. Most MS cases occur sporadically, but a considerable proportion of patients have a family history of MS. The etiology and pathophysiology of MS remain unclear. Recent epidemiological and gene expression studies have indicated that dysregulation of microRNAs (miRNAs) may play a role in MS pathogenesis. This study aimed to evaluate the differential expression of miRNAs in sporadic MS (sMS) and familial MS Materials and Methods: This cross-section, single-center study was conducted in 20 FMS and 10 sMS patients and 8 healthy controls. The patients were in the remission. In total, 2,549 miRNA genes were screened in the blood mononuclear cells from the whole blood samples of MS patients depending on miRBase 21. Differential expression of miRNAs in MS patients was identified compared with the control group, and miRNAs with a fold change >= 2 were validated using reverse transcription-polymerase chain reaction. Differentially expressed miRNAs were then compared between FMS and sMS patients. Results: Initial findings showed that miR-5100 and hsa-miR-16-2-3p were increased and miR-432-3p was decreased in FMS compared with sMS, whereas miR-548-aa, hsa-miR-142-3p, and miR-451-b were increased in both sMS and FMS, but miR-548-v was increased only in sMS. Some miRNAs showed the same expression patterns in both groups. Conclusion: Differential expression of certain miRNAs may be a useful biomarker in the diagnosis of MS. This study showed that miRNAs may discriminate between FMS and sMS cases and MS subtypes, as indicated in earlier studies.Letter Response to the Comment on: Methyl Alcohol Intoxication in Izmir(Galenos Publishing House, 2025) Uysal, Hasan Armagan; Gulluoglu, Halil; Kumcu, Muge Kuzu; Celik, Fatma Nazli DurmazArticle Citation - WoS: 3Citation - Scopus: 3Structural and Functional Changes in Mild Cognitive Impairment in Parkinson's Disease(Mdpi, 2024) Güllüoğlu, Halil; Hünerli, Duygu; Çakmur, Raif; Dönmez Çolakoğlu, Berril; Ada, Emel; Yener, GorsevBackground and Objectives: The pathophysiology of mild cognitive impairment in Parkinson's disease (PD-MCI) is still not fully elucidated. It has been shown in a few studies in the literature that volume loss in the occipital, parietal and frontal cortices and atrophy in the hippocampus of PD-MCI patients can occur in the early stages of PD. The aim of this study was to evaluate the relationship between gray and white matter volumes and different neuropsychological tests and volumetric magnetic resonance imaging parameters in patients with mild cognitive impairment in Parkinson's disease (PD-MCI). Materials and Methods: Twenty-six PD-MCI and twenty-six healthy elderly (HC) were included in this study. Results: We found that Mini Mental State Examination, Trail Making Test Part A, Clock Drawing Test, Benton Line Judgment Orientation Test and pentagon figure-copying scores were impaired in PD-MCI patients due to the decrease in brain volumes. Conclusions: Our study revealed that among PD-MCI patients, there was a more noticeable decline in White matter volume (WMV) based on volumetric Magnetic Resonance Imaging (MRI) compared to the localized loss of GMV. We think that these abnormal neuropsychological tests in PD-MCI patients can be used as pretests in the evaluation of the stage of transition to dementia.Article Citation - WoS: 1Citation - Scopus: 1An Artificial Intelligence Model for Lhermitte's Sign in Patients With Pediatric-Onset Multiple Sclerosis: a Follow-Up Study(Wroclaw Medical Univ, 2025) Uysal, Hasan A.; Poyraz, Turan; Gulluoglu, Halil; Idiman, Fethi; Idiman, EgemenBackground. Lhermitte's sign (LS) is an important clinical marker for patients with multiple sclerosis (MS). Research on pediatric-onset MS (POMS) and LS is limited. To date, there has been no research conducted on the clinical and artificial intelligence (AI)-based radiological correlation of LS. Objectives. This follow-up study aims to investigate the relationship between LS and clinical findings according to AI-based radiological characteristics of patients with POMS. Materials and methods. Basic descriptive statistics of patients with POMS according to sociodemographic, clinical and radiological findings were collected. Variables were evaluated at a 95% confidence level (95% CI), and a value of p < 0.05 was accepted as statistically significant. The LS in patients with MS was classified according to its presence in the past and at the time of the study screening: group A: absent; group B: positive in the past but absent at screening; group C: present both in the past and at the screening; group D: absent in the past but present at the screening. In addition, patients were grouped according to the duration of their MS, with the following classifications: <10 years and at least 10 years. Results. A total of 1,298 records were identified in the database search. Ninety-two patients who met the inclusion criteria were included in the study. The frequency of upper cervical lesions (C1-4 vertebral segmental levels) was higher in group B and C than in group A (p = 0.017). Among patients with an MS duration of 10-years, C1-4 lesions were least frequent in group A. Conclusions. Spinal imaging with AI-based programs can be used at least as much as brain magnetic resonance imaging (MRI) for early diagnosis, prognosis and treatment response. We have for the first time investigated LS in a large sample of patients with POMS. It is, however, recommended to conduct further multicenter studies to more specifically identify LS in patients with POMS.Article İzmir'de Metil Alkol Zehirlenmesi: Retrospektif Analiz(2024) Çelik, Nazlı Durmaz; Kumcu, Müge Kuzu; Uysal, Hasan Armagan; Güllüoğlu, HalilAmaç: Bu çalışmada, İzmir'deki metil alkol zehirlenme vakalarının incelemesi amaçlandı. Hastalar ve yöntemler: Bu retrospektif çalışmaya 1 Ekim 2020-30 Ekim 2020 tarihleri arasında sahte alkollü içecek tüketimi nedeniyle metil alkol zehirlenmesi tanısı konan 15 hasta (14 erkek, 1 kadın; ort. yaş: 56,1±9,3 yıl; dağılım, 40-71 yıl) dahil edildi. Hastalar sağkalıma göre gruplandırıldı. Akut Fizyoloji ve Kronik Sağlık Değerlendirme II skorlaması ve Glasgow Koma Skalası skorları dahil olmak üzere demografik ve klinik veriler karşılaştırıldı. Bulgular: Hastalardan sekizi (%53,3) öldü ve yedisi hayatta kaldı. Hayatını kaybeden ve hayatta kalan hastalar arasında optik sinir tutulumu, mekanik ventilasyon ihtiyacı ve dispne açısından anlamlı bir fark yoktu (sırasıyla p=0,057, p=0,467 ve p=0,467). Bununla birlikte, hayatını kaybeden ve hayatta kalan hastalar arasında radyolojik görüntüleme, görme bozukluğu, gastrointestinal semptomlar ve vazopressör ajan ihtiyacı açısından anlamlı bir fark gözlendi (sırasıyla p=0,044, p<0,001, p=0,011 ve p=0,026). Mortalite; vazopressör ajan ihtiyacı, Akut Fizyoloji ve Kronik Sağlık Değerlendirme II skoru ve Glasgow Koma Skalası skoru ile anlamlı bir şekilde ilişkiliydi (sırasıyla p=0,009; r=0,645, p=0,009; r=–0,652, p=0,008; ve r=0,562, p=0,029). Sonuç: Metil alkol zehirlenmesi, Türkiye'de yaygın ve hatta artan bir sorun olup yüksek mortalite ve morbiditeye neden olmaktadır. Ulusal otoriteler tarafından bu sorunun önüne geçmek için klinik, sosyal ve ekonomik stratejiler geliştirilmelidir.
