The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions
| dc.contributor.author | Merchant, Sabeeha S. | |
| dc.contributor.author | Prochnik, Simon E. | |
| dc.contributor.author | Vallon, Olivier | |
| dc.contributor.author | Harris, Elizabeth H. | |
| dc.contributor.author | Karpowicz, Steven J. | |
| dc.contributor.author | Witman, George B. | |
| dc.contributor.author | Terry, Astrid | |
| dc.contributor.author | Allmer, Jens | |
| dc.date.accessioned | 2023-06-16T14:31:25Z | |
| dc.date.available | 2023-06-16T14:31:25Z | |
| dc.date.issued | 2007 | |
| dc.description.abstract | Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the similar to 120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella. | en_US |
| dc.description.sponsorship | NIGMS NIH HHS [R01 GM042143, GM42143, R01 GM062915-06, R37 GM030626, R37 GM042143, R01 GM042143-09, T32 GM007185, GM07185, R01 GM032843] Funding Source: Medline | en_US |
| dc.identifier.doi | 10.1126/science.1143609 | |
| dc.identifier.issn | 0036-8075 | |
| dc.identifier.issn | 1095-9203 | |
| dc.identifier.scopus | 2-s2.0-35348896591 | |
| dc.identifier.uri | https://doi.org/10.1126/science.1143609 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14365/2100 | |
| dc.language.iso | en | en_US |
| dc.publisher | Amer Assoc Advancement Science | en_US |
| dc.relation.ispartof | Scıence | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Heme-Binding Protein | en_US |
| dc.subject | Photosynthetic Eukaryotes | en_US |
| dc.subject | Intraflagellar Transport | en_US |
| dc.subject | Proteomic Analysis | en_US |
| dc.subject | Fine-Structure | en_US |
| dc.subject | Human-Disease | en_US |
| dc.subject | Reinhardtii | en_US |
| dc.subject | Flagellar | en_US |
| dc.subject | Insights | en_US |
| dc.subject | Genes | en_US |
| dc.title | The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | Lohr, Martin/0000-0002-4335-9887 | |
| gdc.author.id | Pootakham, Wirulda/0000-0001-6721-6453 | |
| gdc.author.id | Elias, Marek/0000-0003-0066-6542 | |
| gdc.author.id | Willows, Robert/0000-0002-0731-2950 | |
| gdc.author.id | Paulsen, Ian T/0000-0001-9015-9418 | |
| gdc.author.id | Terry, Astrid Y/0000-0002-5234-1224 | |
| gdc.author.id | Rajamani, Sathish/0000-0002-5277-6578 | |
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| gdc.author.wosid | Lohr, Martin/A-1214-2009 | |
| gdc.author.wosid | Mueller-Roeber, Bernd/Z-4052-2019 | |
| gdc.author.wosid | Elias, Marek/D-6851-2014 | |
| gdc.author.wosid | Pootakham, Wirulda/F-2358-2011 | |
| gdc.author.wosid | Willows, Robert/C-1537-2010 | |
| gdc.author.wosid | Paulsen, Ian T/K-3832-2012 | |
| gdc.author.wosid | Terry, Astrid Y/A-2538-2011 | |
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| gdc.description.department | İzmir Ekonomi Üniversitesi | en_US |
| gdc.description.departmenttemp | US DOE, Joint Genome Inst, Walnut Creek, CA 94598 USA; Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA; Univ Paris 06, CNRS, Inst Biol Physicochim, F-75005 Paris, France; Duke Univ, Dept Biol, Durham, NC 27708 USA; Univ Massachusetts, Sch Med, Dept Cell Biol, Worcester, MA 01655 USA; Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA; CNRS, Inst Biol Mol Plantes, F-67084 Strasbourg, France; Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA; Zhongshan Univ, Biotechnol Res Ctr, Guangzhou 510275, Peoples R China; Univ Tennessee, Dept Mol Sci, Memphis, TN 38163 USA; Univ Tennessee, Ctr Excellence Genom & Bioinformat, Memphis, TN 38163 USA; Univ Minnesota, Dept Plant Biol, St Paul, MN 55108 USA; Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA; Genet Informat Res Inst, Mountain View, CA 94043 USA; Inst Genom Res, Rockville, MD 20850 USA; Salk Inst Biol Studies, Plant Biol Lab, La Jolla, CA 92037 USA; Stanford Univ, Sch Med, Stanford Human Genome Ctr, Palo Alto, CA 94304 USA; Univ Liege, Inst Plant Biol, Dept Life Sci, B-4000 Liege, Belgium; Univ Nebraska, Sch Biol Sci Plant Sci Initiat, Lincoln, NE 68588 USA; Univ Cambridge, Dept Plant Sci, Cambridge CB2 3EA, England; Univ Calif Berkeley, Dept Plant & Mol Biol, Berkeley, CA 94720 USA; Washington Univ, Sc | en_US |
| gdc.description.endpage | 251 | en_US |
| gdc.description.issue | 5848 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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| gdc.description.volume | 318 | en_US |
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| gdc.identifier.pmid | 17932292 | |
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| gdc.oaire.keywords | Chloroplasts | |
| gdc.oaire.keywords | Proteome | |
| gdc.oaire.keywords | Molecular Sequence Data | |
| gdc.oaire.keywords | Algal | |
| gdc.oaire.keywords | DNA, Algal | |
| gdc.oaire.keywords | Animals | |
| gdc.oaire.keywords | *Genome | |
| gdc.oaire.keywords | Photosynthesis | |
| gdc.oaire.keywords | Biology | |
| gdc.oaire.keywords | [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM] | |
| gdc.oaire.keywords | [SDV.BC] Life Sciences [q-bio]/Cellular Biology | |
| gdc.oaire.keywords | Phylogeny | |
| gdc.oaire.keywords | 580 | |
| gdc.oaire.keywords | Genome | |
| gdc.oaire.keywords | Algal Proteins | |
| gdc.oaire.keywords | Computational Biology | |
| gdc.oaire.keywords | Membrane Transport Proteins | |
| gdc.oaire.keywords | Genetics and Genomics | |
| gdc.oaire.keywords | Plant Breeding and Genetics | |
| gdc.oaire.keywords | DNA | |
| gdc.oaire.keywords | Cell Biology | |
| gdc.oaire.keywords | Genomics | |
| gdc.oaire.keywords | Sequence Analysis, DNA | |
| gdc.oaire.keywords | Plants | |
| gdc.oaire.keywords | Biological Evolution | |
| gdc.oaire.keywords | *Evolution | |
| gdc.oaire.keywords | Genes | |
| gdc.oaire.keywords | Flagella | |
| gdc.oaire.keywords | Animal Sciences | |
| gdc.oaire.keywords | Multigene Family | |
| gdc.oaire.keywords | Sequence Analysis | |
| gdc.oaire.keywords | Chlamydomonas reinhardtii | |
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