Evaluation of the Relationship Between Prognostic Nutritional Index and Early Clinical Outcomes in Intestinal Transplantation

Abstract

Background: Malnutrition in patients with intestinal insufficiency negatively affects the success of intestinal transplantation. In our research, we assessed patients' nutritional status using the PNI scale and examined the impact of the PNI score on clinical outcomes during the post-transplant phase. Results: The acute rejection rate was 38.1%, and the 30-day survival rate was 90.5%. Median PNI values were 41.5 (min-max: 33.5-65), 29.5 (min-max: 13.5-56.5), 33 (min-max: 3-51), 35.7 (min-max: 24.5-54), 33.5 (min-max: 24.5-75.5) preoperatively and on postoperative 1, 7, 15, and 30 days, respectively. No significant relationship was found between the other parameters and the PNI. Conclusions: The PNI score alone fails to adequately represent a patient's nutritional status and has not demonstrated effectiveness in predicting early-term outcomes for those undergoing intestinal transplantation. Additional studies involving a larger number of patients and diverse nutritional markers are necessary for further insights into this matter. © 2025 Elsevier B.V., All rights reserved.