TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/4

Browse

Now showing 1 - 15 of 15

Citation - Scopus: 1
Affecting Factors in Medication Adherence in Kidney Transplant Recipients
(Aves, 2023) Ordin, Yaprak Sarigol; Karayurt, Ozgul; Ertan, Nermin; Edeer, Aylin Durmaz; Yildiz, Serkan
Objective: This study aimed to determine the risk factors related to immunosuppressive medication adherence in kidney transplant recipients. Methods: The study adopted a retrospective design. It was carried out on 208 kidney transplant recipients. The social cognitive theory was used for understanding and addressing the issues of nonadherence to immunosuppressive medication. Data were collected with a self-reported-Immunosuppressant Therapy Adherence Scale and biological assays. Descriptive analyses and logistic regression were used to analyze data. Results: According to the self-reported assessment, medication adherence of the patients receiving transplants from live donors was 0.503 times lower than that of the patients receiving transplants from deceased donors. The biological assays did not show any affecting factors in medication adherence. Conclusion: The results of the study showed the importance of combining methods to assess medication adherence. In the self-reported assessment, live donor transplantation was found to negatively affect medication adherence. Turkiye is the country with the highest number of kidney transplantations from live donors in the world. Health professionals must be more careful in assessing medication adherence after live donor transplantations.
Citation - WoS: 15
Citation - Scopus: 14
Changes on Hepatitis C Virus Genotype Distribution in Western Turkey: Evaluation of Twelve-Year Data
(Aves, 2020) Duran, Alev Cetin; Cetinkaya, Ozgul Kaya; Sayiner, Ayca Arzu; Seydaoglu, Gulsah; Ozkaratas, Emre; Abacioglu, Hakan
Background/Aims: Hepatitis C virus (HCV) prevalence is 1% in Turkey with genotype 1 being the predominant type traditionally. However unique geographical location of Turkey and increasing human migration in the region influences the epidemiology of the infection. The aim of this study was to determine the changes in distribution of HCV genotypes and risk factors. Materials and Methods: In this retrospective single-center study, HCV genotyping results of 558 patients were evaluated in between 2005 and 2016.Three different HCV genotyping assays were used during the 12-year study period;restriction fragment length polymorphism (RFLP), Abbott Real Time HCV Genotype II and Bosphore HCV genotyping kit. Results: The most prevalent HCV genotype was genotype 1 detected in 88.4% of the patients followed by genotype 3 (5.2%),genotype 4 (2.9%),genotype 2 (2.1%), mixed genotypes (1.1%) and genotype 5 (0.3%). Genotype 1a showed an increasing prevalence. There were 19 patients (3.4%) either of foreign nationalities or Turkish citizens living abroad. Genotype 3 was the most common type among these patients which 10.3% had intravenous drug use history. Syrian migrant population differed in terms of HCV genotypes. Genotype 5 detected in two Syrian patients, which is the first report of HCV type 5 in Western Turkey. Among the HCV genotype 4 infected patients, 31.3% were Syrians. Conclusion: Our study showed that although genotype 1b dominance continues, the distribution and prevalence of HCV genotypes are changing in our region mainly due to migration and increase in the frequency of patients with non-traditional risk factors such as intravenous drug use. Monitoring the epidemiology of HCV genotypes may provide guidance in treatment decisions.
Citation - WoS: 3
Citation - Scopus: 3
A Combination of Heart Rate-Corrected Qt Interval and Grace Risk Score Better Predict Early Mortality in Patients With Non-St Segment Elevation Acute Coronary Syndrome
(Aves, 2022) Inci, Saadet Demirtas; Tekindal, Mustafa Agah; Altinsoy, Meltem; Ozbeyaz, Nail Burak; Sunman, Hamza; Tas, Alperen; Yilmaz, Sabiye; Güllü, Hakan
Objective: This study aimed to evaluate whether the addition of heart rate-corrected QT interval prolongation to the Global Registry of Acute Coronary Events risk score improves the predictive value for early mortality in patients with non-ST segment elevation acute coronary syndrome. Methods: We retrospectively screened our database for consecutive non-ST-segment elevation acute coronary syndrome patients between January 2017 and July 2019. The demographic and clinical parameters were acquired via chart review. All electrocardiograms were reviewed by 2 physicians. QT interval was measured using the tangent method. Early mortality was defined as all-cause death observed during the hospital stay or within 30 days after discharge. Results: The final study population consisted of 283 patients, there were 17 early deaths. Ten of 59 patients with prolonged corrected QT intervals died (16.9%, P < .001). Both the Global Registry of Acute Coronary Events risk score (odds ratio: 1.032; 95% CI: 1.012-1.053; P = .002) and corrected QT interval (odds ratio: 1.026; 95% CI: 1.007-1.045; P = 0.007) independently predicted early mortality. The area under value was 0.769 (95% CI: 0.674-0.863, P < .001) for the corrected QT interval and 0.780 (95% CI:0.681-0.878; P < .001) for the Global Registry of Acute Coronary Events risk score alone. However, when the corrected QT interval and the Global Registry of Acute Coronary Events risk score were combined, it was found to be 0.808 (95% CI: 0.713-0.904, P < .001). Conclusion: This study is the first to report that prolonged corrected QT and the Global Registry of Acute Coronary Events risk score independently predict early mortality and a combination of these 2 factors may improve the predictive value for early mortality in patients with ST-segment elevation acute coronary syndrome.
Citation - WoS: 1
Comparison of Pulmonary Functions, Physical Activity Level and Quality of Life in Obese and Pre-Obese Individuals
(Aves, 2017) Aktan, Ridvan; Ozalevli, Sevgi
Objective: There are studies regarding pulmonary functions of obese individuals in literature; however, there is insufficient data regarding pre-obese individuals. This study aimed to compare the pulmonary functions, physical activity levels, and health-related quality of life (HRQOL) of obese and pre-obese individuals. Methods: The characteristics of 62 subjects participating in the study were recorded All subjects were evaluated using pulmonary function tests (PFT), short form-36 health survey (SF-36), obesity and weight loss quality of life measure (OWLQOL), international physical activity questionnaires (IPAQ), and modified medical research council (mMRC) scale. Results: The severity of perceived dyspnea in obese subjects was significantly higher than that in pre-obese subjects. The PFT parameters (FVC, FEV 1, PEF, FEF 25-75, FEF 25-75 %, MVV, and MVV%) were significantly lower in obese subjects. Although individuals in both groups were inactive, the inactivity levels in obese subjects were significantly higher. HRQOL scores were significantly lower in obese individuals. The body mass index (BMI) was significantly correlated with dyspnea severity, SF-36 subscores, OWLQOL scores, and PFT parameters. Conclusion: While an increasing BMI has an adverse effect on the pulmonary functions of pre-obese individuals, increased BMI coupled with reduced pulmonary functions causes a decrease in the physical activity levels and reduces HRQOL of obese individuals.
Citation - WoS: 3
Citation - Scopus: 5
Current Status of Kidney Replacement Therapy in Türkiye: a Summary of 2022 Turkish Society of Nephrology Registry Report
(Aves, 2024) Seyahi, Nurhan; Kocyigit, Ismail; Eren, Necmi; Tonbul, Halil Zeki; Tatar, Erhan; Yilmaz, Zulfukar; Ates, Kenan; Oguz, Ebru Gok
Background: Turkish Society of Nephrology registry collects data on hemodialysis, peritoneal dialysis, and transplantation annually. Registry reports are printed every year as a booklet, and this is the 33rd year of registry reports. The registry is in close collaboration with international registries. Methods: In this paper, we summarized data from the 2022 registry report; additionally, we also provided yearly trends of managing end-stage kidney disease. Results: The number of patients on kidney replacement therapy increases; at the end of 2022, 86 665 patients were on kidney replacement therapy. The prevalence and incidence of end-stage kidney disease were 1016.2 and 160.9 per million population, respectively. Diabetes was the most common cause of end-stage kidney disease. Hemodialysis (71.22%) was the most common type of treatment modality, followed by transplantation (24.68%) and peritoneal dialysis (4.1%). Conclusion: End-stage kidney disease is a critical and growing health problem for our country. The renal registry of the Turkish Ssociety of Nephrology is one of the leading tools for providing current and sound data on this public health problem.
Determining the Effects of the Monitoring and Counseling in Addition To Standard Monitoring on the Abstinence After Quit Smoking: a Randomized Controlled Study
(Aves, 2020) Gulesen, Asli; Yavan, Tulay; Bebis, Hatice
BACKGROUND/AIMS The aim of this study was to determine the effects of supplemental monitoring and counseling in addition to the standard monitoring during the treatment period on the abstinence behavior of smoking cessation center applicants. MATERIAL and METHODS The randomized controlled study was conducted in the smoking cessation clinic as an intervention study. The study involved 67 participants. Data collection was implemented using the Descriptive Questions Form, Fagerstrom Test for Nicotine Dependence, Carbon Monoxide Monitoring Chart, and Self-Efficacy Questionnaire. After routine standard training and tests at the smoking cessation center, a total of six supplemental interviews were conducted in the intervention group by one of the researchers; these interviews were conducted one week before smoking cessation and one week and one, Iwo, three, and six months after quitting. Two interviews were conducted in the control group for evaluation: one week before and six months after quitting. RESULTS After six months, 88.2% of the intervention group and 60.6% of the control group had stopped smoking. A statistically meaningful difference was found between the intervention and the control groups in terms of attending the standard monitoring. In the last interview, the self-efficacy score of the intervention group was significantly higher than that in the control group. Compared to the control group, the intervention group was 1.5 times more successful in smoking cessation at the end of the sixth month. CONCLUSION Those successful in smoking cessation must be monitored in frequent follow-ups simultaneously supported by physicians, nurses, and other health-care providers.
Citation - WoS: 8
Citation - Scopus: 7
Electrogastrography in Patients With Functional Dyspepsia, Joint Hypermobility, and Diabetic Gastroparesis
(Aves, 2022) Al Kafee, Abdullah; Cilaci, Talar; Kayar, Yusuf; Akan, Aydin
Background: Transcutaneous electrogastrography is a novel modality to assess the human stomach's gastric myoelectrical activity. The purpose of this study was to compare functional dyspepsia, joint hypermobility, and diabetic gastroparesis patients with healthy control subjects in terms of gastric motility abnormalities through electrogastrography evaluations, and to then evaluate the correlation among variations in their blood parameters. Methods: This study analyzed 120 subjects with functional dyspepsia (n = 30), joint hypermobility (n = 30), diabetic gastroparesis (n = 30), and control subjects (n = 30). The electrogastrography parameters included the dominant frequency, dominant power, power ratio, and instability coefficient, which were analyzed preprandially and postprandially. Although there are similar studies in the literature, there is no other study in which all groups have been studied together, as in our study. Results: The electrogastrography results showed that preprandial dominant frequency (P = .031*) dominant power (P = .047*) and instability coefficient (P = .043*) and postprandial dominant frequency (P = .041*) and dominant power (P = .035*) results were statistically significant among the functional dyspepsia, joint hypermobility, diabetic gastroparesis, and control groups. There was no significant difference found in terms of power ratio (P= .114) values. However, only glucose (P = .04*) and calcium (P = .04*) levels showed statistical significance. Several blood tests including hemoglobin (P = .032*) creatinine (P= .045*) calcium (P = .037*), potassium (P= .041*), white blood cells (P = .038*), and alanine aminotransferase (P = .031*) also showed correlation with the dominant frequency, power ratio, and instability coefficient parameters. Conclusions: This joint methodology demonstrated that it is possible to differentiate between functional dyspepsia, joint hypermobility, and diabetic gastroparesis patients from healthy subjects by using electrogastrogrophy. Moreover, the majority of patients showed dequate gastric motility in response to food.
Citation - WoS: 19
Citation - Scopus: 17
Evaluation of Illness Perception of Women With Breast Cancer in Turkey
(Aves, 2019) Karabulutlu, Elanur Yilmaz; Avci, Iliknur Aydin; Karayurt, Orgul; Gursoy, Ayla; Kosgeroglu, Nedime; Tuna, Arzu; Ersin, Fatma
Objective: The aim of this study is to examine the illness perceptions of women with breast cancer and possible relationships between these perceptions and descriptive characteristics such as sociodemographic and clinical characteristics in Turkey. Materials and Methods: The study was conducted in compliance with correlational, descriptive research principles. Three hundred eighty women with breast cancer who were treated in various hospitals in seven regions of the country were included in the study. A sociodemographic and clinical characteristics form, and The Illness Perception Questionnaire were used for data collection. Results: The mean age of the patients with breast cancer was 49.8 +/- 11.5, among them, 83.95% were married, 37.37% were at stage 2 breast cancer, and 67.11% experienced mastectomy. It was found that the patients perceived higher personal control over illness (20.88 +/- 4.76). The patients perceived most common risk factors as the cause of the illness (19.42 +/- 6.38). This study show that variety sociodemographic and clinical characteristics of the patients affected their perceptions of illness. Conclusion: The meaning of illness from the perspective of patient with breast cancer should be assessed. The care, education and counselling programs should be planned according to the patient's illness perceptions.
Citation - WoS: 4
Citation - Scopus: 4
Evaluation of Psychosocial Outcomes of Living Liver Donors in Liver Transplantation
(Aves, 2022) Ordin, Yaprak Sarigol; Seren, Arzu Kader Harmanci; Karayurt, Ozgul; Kul, Gulay Aksu; Kılıç, Murat; Bozoklar, Cemal Ata; Tokat, Yaman; Harmancı Seren, Arzu Kader
Background: The purpose of this study was to evaluate the risk factors affecting psychosocial outcomes of living liver donors after liver transplantations. Methods: This was a descriptive, cross-sectional study. The sample consisted of living liver donors followed by 2 liver transplantation centers in 2 private hospitals in 2 different provinces, between August 2017 and October 2019. All the living liver donors were contacted without a time frame after donation and all the participants were evaluated once. The Beck Depression Scale, SF-36, General Self-Efficacy Scale, and Perceived Available Support Scale were used to collect data. The t-test, Kruskal-Wallis test, Mann-Whitney U-test, and Pearson correlation analysis were used for data analysis. Results: The mean age of the patients was 34.31 +/- 8.22 years. There was a positive, weak correlation between age and physical function. Gender, marital status, financial status, and education levels significantly affected physical components, social function, vitality, depression, and self-efficacy scores. High depression levels negatively affected the physical component, self-efficacy, and social support scores of the living liver donors. High self-efficacy positively affected social support. Conclusion: The study revealed that gender, marital status, employment status, and education levels were associated with psychosocial outcomes. The financial status was the main factor affecting each psychosocial variable. Financial status needs to be assessed in detail before and after the operation.
Citation - WoS: 1
Citation - Scopus: 2
Evaluation of Treatment Safety in Patients With Atrial Fibrillation on Edoxaban Therapy in Real-Life in Turkey Study: Design and Rationale
(Aves, 2022) Türk Uğur Önsel; Alioglu, Emin; Mavioglu, Zafer; Diker, Erdem; Ozpelit, Ebru; De Caterina, Raffaele; Türk, Uğur Önsel
Objective: Safety and effectiveness of edoxaban was demonstrated in phase III, Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48 (ENGAGE-AF-TIMI 48) trial and is being confirmed in the post-authorization Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study in patients with atrial fibrillation. However. any post-authorization safety study focusing on the safety of edoxaban treatment in Turkey with a prospective design has not been performed yet. The Evaluation of Treatment Safety in Patients with Atrial Fibrillation on Edoxaban Therapy in Real-Life in Turkey (ETAF-TR) study is designed to evaluate the safety and effectiveness of edoxaban treatment in atrial fibrillation in routine practice. The present article describes the design and rationale for the ETAF-TR Study. Methods: The ETAF-TR (NCT04594915) is a national. multicenter. prospective, observational study that enrolled 858 patients from 32 centers. The primary outcome of the ETAF-TR study is any overt bleeding (consisting of major bleeding or clinically relevant nonmajor bleeding or any bleeding that does not meet this definition but is considered as overt bleeding by the participating physician). Effectiveness, treatment persistence. and posology will also be evaluated in an explorative manner. The overall duration of follow-up will be 1 year: the first patient was enrolled in August 2020. Conclusions: Results of ETAF-TR wilt add data from clinical practice to those from ENGAGE-AF trial and also ETNA-AF study. Comparing their results will enable to test the external validity of ENGAGE-AF trial in the country conditions.
Citation - WoS: 1
Citation - Scopus: 1
Healthcare-Related Hcv Genotype 4d Infections in Kayseri, Turkey
(Aves, 2022) Gokahmetoglu, Selma; Polat, Ceylan; Atalay, Mustafa Altay; Sezgin, Gulten Can; Ergor, Gul; Aygen, Bilgehan; Gursoy, Sebnem; Abacıoğlu, Yusuf Hakan; Gökahmetolu, Selma; Abacolu, Yusuf Hakan
Background: The frequency of genotype 4 hepatitis C virus infection is significantly higher in a city compared to other provinces in Turkey. In this study, we aimed to investigate the epidemiology and risk factors of hepatitis C virus genotype 4 infection in Kayseri province of Turkey. Methods: A case-control study was conducted with 61 hepatitis C virus genotype 4-infected patients and 71 controls. A questionnaire was administered to the patients and controls, asking for information about the risk factors of hepatitis C virus transmission. Core/E1 and NS5B regions of hepatitis C virus genome were amplified and sequenced by Sanger method. Phylogenetic analysis and molecular clock analysis were performed. The risk was determined by calculating the odds ratio and 95% CI. Logistic regression analysis was performed to determine the effect of risk factors by controlling for confounding variables. Results: Kayseri isolates were closely related to type 4d sequences but formed a separate cluster. According to the molecular clock analysis, hepatitis C virus genotype 4d entered Kayseri province probably between 1941 and 1988. Blood transfusion and surgical intervention were found to be significant risk factors for the infection. Conclusion: Epidemiological data showed that hepatitis C virus genotype 4d infections are significantly associated with unsafe medical procedures.
Citation - WoS: 1
Citation - Scopus: 2
A New Era in Psychiatry: Influence of Technology and Artificial Intelligence
(Aves, 2019) Erol, Kutluhan
[Abstract Not Available]
Citation - WoS: 7
Citation - Scopus: 8
Solid Pseudopapillary Neoplasms of the Pancreas: Case Series With a Review of the Literature
(Aves, 2020) Uguz, Alper; Unalp, Omer Vedat; Akpinar, Goksever; Karaca, Can Avni; Oruc, Nevin; Nart, Deniz; Yilmaz, Funda
Background/Aims: The solid pseudopapillary neoplasms are quite rare tumors of the pancreas, comprising roughly 1-2% of all pancreatic neoplasms. It has a low malignant potential and usually affects young females. Despite increasing number of articles in the last decade, there is still debate on the pathogenesis, malignant potential and optimal surgical strategy for the solid pseudopapillary neoplasms. Materials and Methods: Medical recordings of 326 patients who were operated due to pancreatic mass were retrospectively analyzed. Patient demographics, presenting symptoms, surgical and pathologic characteristics of the tumor, postsurgical course, long-term survival, and other relevant data were extracted from patients' charts. Results: Majority of the patients were female in consistency with the classic data in the literature. All the patients underwent curative intent resections. Tumors were commonly localized in the tail of the pancreas making distal pancreatectomy the most commonly performed surgical procedure. Mean tumor diameter was 5.8 centimeters with tumor sizes ranging from 1 to 19 cm. Conclusion: The solid pseudopapillary neoplasms of the pancreas is a rare tumor with low malignant potential, which is more common in females of reproductive age, with abdominal pain being their most common presentation. The short-term outcomes in patients following surgical R0 resection are excellent. However, proximal placement of the tumor and female gender may have slightly worse prognosis. We hope that our findings from a series of patients represent a contribution to the existing literature on SPN, and authors declare their willingness to provide further details for future meta-analyses.
Turkish Adaptation and Validation of Behavioral Inhibition Questionnaire Parent Form
(Aves, 2022) Kilinc, Saliha; Bilgiç, Ayhan; Gormez, Vahdet
Background: Behavioral inhibition has been proposed as a temperamental risk factor for the development of childhood anxiety disorders universally; however, there is no validated instrument for, especially, its evaluation in Turkish children. This study aimed to examine reliability and validity of the Turkish version of Behavioral Inhibition Questionnaire parent form for children aged 3-7 years. Methods: Around 250 mothers or fathers of 3-7 years old children were recruited from non-clinical population to collect responses to the questionnaires. The sample was created by reaching 3 schools at preschool or elementary grade for the purpose of providing the questionnaires filled about the student and/or his/her little sisters and brothers by their parents; questionnaires were sent out to parents and then gathered. Parents were asked to fill sociodemographic data form, Behavioral Inhibition Questionnaire parent form, Children Behavior Questionnaire, and Strengths and Difficulties Questionaire parent form in order to perform convergent and divergent validity analyses. Results: As a result of reliability analysis, total Cronbach alpha coefficient for Behavioral Inhibition Questionnaire was determined as 0.92 with strong reliability. The internal consistency coefficients for Behavioral Inhibition Questionnaire subscales also showed strong reliability with alphas ranging between 0.81 and 0.87 except for the performance (a = 0.69) and physical challenges (a = 0.19) subscales of which some items were excluded due to item-total correlations and confirmatory factor analysis results. In the validity assessment analyses, confirmatory factor analysis demonstrated that Behavioral Inhibition Questionnaire has a construct validity with 5 factors loaded on the 2-second order main factors and one third-order final factor (root mean square error = 0.032, root mean square residual = 0.153, Comparative Fit Index = 0.978, Goodness of Fit Index = 0.915, and Turker-Lewis Index = 0.970). While the strongest correlations with the overall Behavioral Inhibition Questionnaire score were found for 2 main subscales, inhibition to social novelties (r = 0.926, P <.001) and situational novelties (r = 0.928, P <.001), similarly peers (r = 0.848, P <.001) and new situations (r = 0.898, P <.001) subscales, had strong correlations with the overall Behavioral Inhibition Questionnaire score. The weakest correlation with overall Behavioral Inhibition Questionnaire score was observed for physical challenges subscale even though this subscale displayed moderate association (r = 0.454, P <.001). A good convergent validity was determined accompanied by significant moderate positive correlations with Children Behavior Questionnaire shyness and Strengths and Difficulties Questionnaire internalizing scales. An adequate divergent validity was also demonstrated based on significant positive mild to moderate correlations with Children Behavior Questionnaire impulsivity, Children Behavior Questionnaire smiling/laugh, Strengths and Difficulties Questionnaire prosocial scales, and nonsignificant correlation with Strengths and Difficulties Questionnaire externalizing scale. Conclusion: The study demonstrated that the Turkish version of the Behavioral Inhibition Questionnaire parent form is an effective tool with good reliability and validity among 3-7 years old children.
Citation - WoS: 18
Citation - Scopus: 23
Urban and Rural Differences in Hypertension Risk Factors in Turkey
(Aves, 2017) Dastan, Ilker; Erem, Ayşegül; Cetinkaya, Volkan
Objective: Existing literature shows considerable regional differences in terms of hypertension (HT) prevalence in Turkey. The purpose of this study was to analyze some of the known HT risk factors contributing to the variations between urban and rural areas of Turkey in HT development. Methods: We used data from the 2011 Chronic Diseases and Risk Factors Survey that was conducted by the Turkish Ministry of Health on a representative sample of the Turkish adult population aged 20 years or more (n=16.227). HT was defined as having at least one of the following: a mean systolic/diastolic blood pressure of at least 140/90 mm Hg, a previously diagnosed disease, or use of antihypertensive medication. Stepwise multiple logistic regression analysis was used to estimate HT risk factors in urban and rural settings. Results: Although the HT prevalence was higher in rural areas (28.4%) than in urban areas (23.9%), in this study, urbanization was found to be a contributing factor in multivariate regression analysis. Furthermore, separate regressions for urban and rural settings revealed that age, obesity, diabetes, hyperlipidemia, and smoking were independently and positively associated (p<0.05) with HT in both settings, while marital status, employment type, mental health, and lifestyle patterns; nutritional habits; and amount of physical activity and sedentary time (p<0.05) were risk indicators in urban areas only. Conclusion: The findings of our study demonstrate that contributory factors show some variations between urban and rural settings, and on gender within each setting. Taking into account the variations between urban and rural areas in HT development may provide greater insight into the design of prevention strategies.

Browse

Browsing TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection by Publisher "Aves"