TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14365/4

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Browsing TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection by Subject "Age"

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    Article
    Citation - WoS: 9
    Citation - Scopus: 9
    Classical Heart Rate Variability and Non-Linear Heart Rate Analysis in Mice Under Na-Pentobarbital and Ketamine/Xylazine Anesthesia
    (Tubitak Scientific & Technical Research Council Turkey, 2022) Kazdagli, Hasan; Ozel, Hasan Fehmi; Ozbek, Mustafa; Alpay, Suheda; Alenbey, Muruvvet
    Background/aim: Anesthetics are often used in animal experiments to achieve immobilization and relieve pain. However, many anesthetics can alter the dynamics of cardiovascular systems. We aimed to compare the effects of two frequently used anesthetics agents on heart rate variability (HRV) parameters in mice. Materials and methods: This observational study was performed between May and June 2014 in 21 male BALB/c mice aged 16-20 weeks. The animals were divided into three groups: pentobarbital (P), (n = 7); pentobarbital+fentanyl (P+ F), (n = 7); and ketamine+xylazine (K+X), (n = 7). Surface electrocardiography (ECG) electrodes were placed in lead II configuration. 'the tachogram of RR intervals was obtained after R waves were detected using the Pan-Tompkins real-time QRS recognition algorithm. Frequency-domain, time-domain, and nonlinear HRV analyses were performed. Results: The bradycardia effect was higher in the K+X group (p < 0.01). Time-domain indices were higher in group K+X compared to group P (p < 0.01) and group P+F (p < 0.001). Very low frequency (VLF) power was significantly lower in group K+X compared to group P and group P+F (p < 0.01). Low frequency (LF) power, low frequency/high frequency (LF/HF) ratio, and total power (TP) were higher in group K+X compared to group P (p < 0.01) and group P+F (p < 0.001). The detrended fluctuation analysis short-term parameter (DFA alpha(1)) was significantly higher in group K+X compared to group P+F (p < 0.05) and the long-term parameter (DFA alpha(2)) was lower in group K+X compared to group P (p < 0.05). Standard deviations SD1 and SD2 were higher in group K+X compared to group P (p < 0.001) and group P+F (p < 0.001), SD2/SD1 ratio was lower in group K+X compared to group P (p < 0.05) and group P+F (p < 0.05). Entropy measures did not differ between groups. Conclusion: HRV analyses, including nonlinear methods, indicated that a K+X combination reduces imbalance and disorder in the regulation of the autonomic nervous system (ANS) in comparison to both P and the P+F combination.
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    Article
    Citation - WoS: 8
    Citation - Scopus: 7
    Evaluation of Demographic and Clinical Characteristics of Female Patients Presenting With Minoca and Differences Between Male Patients: a Subgroup Analysis of Minoca-Tr Registry
    (Kare Publ, 2022) Gok, Gulay; Coner, Ali; Cinar, Tufan; Kilic, Salih; Yenercag, Mustafa; Oz, Ahmet; Ekmekci, Cenk
    Objective: Although the prevalence and rate of myocardial infarction with non-obstructive coronary arteries (MINOCA) are higher in women than in men in previous cohorts, potential demographic and clinical differences between women who are diagnosed with MINOCA versus myocardial infarction with obstructive coronary arteries (MIOCA) have not been studied till date. In this study, we aimed to document these characteristics and to compare them between female patients with MINOCA and MIOCA. Methods: The study was a subgroup analysis of the MINO-CA-TR study. The study was a multi-center, observational cohort study that was conducted in Turkey between March 2018 and October 2018. In this study, 477 (29.3%) female patients who had been diagnosed with acute myocardial infarction were evaluated. Results: Of these women, 49 (10.3%) were diagnosed with MINOCA (mean age 58.9 +/- 12.9 years) and 428 (89.7%) had a final diagnosis of MIOCA (mean age 67.4 +/- 11.8 years). The prevalence of hypertension, hyperlipidemia, and diabetes mellitus was significantly lower in the MINOCA group than in the MIOCA group. In addition, the MINOCA group had higher rates of recent flu history and non-ST elevation myocardial infarction (NSTEMI) presentation than the MIOCA group. There were significant clinical differences in patients with MINOCA in terms of sex. The female patients were older, had higher systolic blood pressures, and lower hemoglobin levels than male patients. Conclusion: The study revealed that the prevalence of traditional coronary artery disease risk factors was lower in female patients with MINOCA than in those who had final diagnosis of MIOCA.
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    Article
    Citation - WoS: 3
    The Role of Community-Based Health Practice on the Improvement of Healthcare Students' Communication, Empathy and Perception of the Elderly: a Qualitative Study at Izmir University of Economics
    (Istanbul Univ, Fac Communication, 2021) Aksoy, Zeynep; Gokdemir, Ozden; Şemin, Makbule İlgi
    Interpersonal communication involving empathy is of great importance in therapeutic relationships in healthcare. To equip medical/healthcare students with interpersonal communication skills, community-based health education provides real-life contexts in which they engage with the community as part of the curriculum. A community-based health practice (CBHP) was implemented at Izmir University of Economics (IUE) to improve students' communication, empathy and perception towards the elderly. Within an interdisciplinary collaboration among the medicine, nursing, elderly-care and physiotherapy programs, a total of 111 students participated in the project. This study aimed to evaluate the role of the CBHP on students' communication, empathy and perception of the elderly. Taking a qualitative approach, focus group interviews were organized with students (n=22). Descriptive analysis of the qualitative data revealed that students witnessed the loneliness of elderly individuals, their physical and psychosocial needs, which resulted in a high degree of empathy. Furthermore, the study also aimed to gain insights from elderly participants via in-depth interviews (n=9). Results demonstrated that the participants felt valued and useful during the communication processes with the students. In conclusion, CBHP contributed to students' perceptions and empathy towards the elderly; meanwhile the elderly individuals were satisfied with the interest of the medical, nursing and healthcare students.