TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
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Article 1,25-Dihydroxyvitamin D3 Induces N-Myc Downstream Regulated Gene-2 Expression in Papillary Thyroid Carcinoma Cells(Dokuz Eylul Univ Inst Health Sciences, 2020) Sipahi, Murat; Bartik, Didem Keles; Doruk, Mehmet; Bayraktar, Firat; Oktay, GulgunPurpose: In addition to its role in serum calcium homeostasis, the anti-tumor function of 1,25-dihydroxyvitamin D-3 (calcitriol) in cancer development is well established. N-myc Downstream Regulated Gene 2 which functions as a tumor suppressor gene has recently been shown to be downregulated in various cancer leading to increased tumor incidence, progression and metastasis. The goal of this study was to investigate the possible effects of calcitriol treatment on NDRG2 expression in BCPAP papillary thyroid carcinoma cells. Methods: The experiments were carried on human primary thyroid follicular epithelial cells (Nthy-ori-3-1), and human papillary thyroid carcinoma cells (BCPAP). The half maximal inhibitory concentration (IC 50) of calcitriol on BCPAP cells was determined by WST-1 assay. BCPAP cells were treated with 15 and 30 mu M calcitriol for 24, 48, and 72 hours, respectively. Basal NDGR2 expression in Nthy-ori-3-1 and BCPAP cells as well as the alterations on NDRG2 expression in calcitriol treated BCPAP cells were evaluated with western blot. Results: A significant downregulation of NDRG2 was observed in BCPAP cells when compared to Nthy-ori-3-1 cells (p<0.01). IC50 dose of calcitriol was found to be 64, 54 and 43 mu M for 24, 48 and 72 hours, respectively. NDRG2 protein expression levels were significantly increased in 30 mu M calcitriol treated BCPAP cells after 48 hours (p<0.05). Conclusions: Calcitriol induced NDRG2 protein expression in BCPAP cells. We predict that calcitriol increased NDRG2 protein levels in BCPAP cells via c-Myc repression, which is upregulated by aberrant Wnt/beta-catenin signaling. Further investigation is required to enlighten the possible effect mechanisms of calcitriol in BCPAP cells.Article 2011-2013 Constitution-Making Process and Media Field in Turkey(2019) Akın, Altuğ; Yaman Akyar, BurcuThis paper examines so-called “Constitutional Process” which took place between 2011 and 2013 in Turkey to eventually fail after more than two years of intense work and rise of expectations both in Turkish society and international community from the perspective of media and communications. How Turkish media influenced the constitution making process including workings of Constitutional Conciliation Commission is discussed, surveying relevant media content or performance with a particular focus on the political economy of Turkish media during that period. Traditional media outlets such as newspapers and television channels, and nowadays largely digital platforms, function as present-day agoras where political agenda is determined and contested. These online and offline channels have different levels of influence on discussions of the political elite, as presented extensively in media and communication studies. Together with the global media environment, national media foster the emergence of its own elites, while maintaining multi-layered relationships with high-level political decision-making processes. Media channels therefore bear symbolic powers that impact political policymaking by employing methods such as agenda setting and framing. In this line of thought, this article approaches Turkish media space as a specific field while its content and its political economy are examined in relation with the constitution making process to reveal the role played by media during highly politicized processes, such as constitution making, as well as eliciting the dynamics that herald such media performance.Article Citation - WoS: 1Citation - Scopus: 125-Hydroxyvitamin Levels in Sjögren’s Syndrome: Is It the Right Time to Dismiss the Case or Not(Walter de Gruyter GmbH, 2024) Sımsır, Ilgın Yıldırım; Tanigor, Goksel; Karabulut, Gonca; Barutcuoglu, Burcu; Yılmaz, ZevcetObjectives: This study aimed to investigate whether patients with primary Sjögren syndrome (SjS) have different levels of 25 OH-D3 (vitamin D) when compared to healthy populations and whether differences in 25 OH-D3 correlated with disease activity or markers. Methods: Eighty-eight female patients with SjS and 3,338 age-matched healthy female controls were included in this study. 25 OH-D3 levels were compared with healthy controls. Then the patients were stratified according to their 25 OH-D3 levels, either insufficient/deficient or normal (<50 nmol/L or ≥50 nmol/L). The disease activity was evaluated using The EULAR SjS disease activity index (ESSDAI) and its components. Correlation analyses were also performed for a possible correlation with disease characteristics and markers of activity. Results: No differences in 25 OH-D3 levels were found between SjS and healthy populations (p>0.05). No correla- tions were found between patient characteristics or labo- ratory values (p>0.05). Conclusions: This study did not find a link between disease characteristics and disease activity and 25 OH-D3 levels. Prospective studies with more patients should be conducted to reach a conclusion.Letter Citation - WoS: 1Citation - Scopus: 1About The Article Titled “a Different Scintigraphic Perspective On The Systolic Function Of The Left Ventricle-1” [“sol Ventrikül Sistolik Fonksiyonuna Sintigrafik Olarak Farklı Bir Bakış Açısı-1” Başlıklı Makale Hakkında](Galenos Publishing House, 2024) Taşçı, Cengiz[No abstract available]Article Absence of Costal Element of the Foramen Transversarium of Atlas Vertebrae: a Case Report(2018) Hayran, Mürvet; Yonguç, Gökşin Nilüfer; Baylan, HüseyinWe detected an atlas vertebra of which costal elements of its foramen transversarium were not developed bilaterally. The costal elementis an arch of bone that form the anterior portion of foramen transversarium. The vertebral arteries running towards cranial cavity aresurrounded and protected by foramina transversarium of upper six cervical vertebrae. Surgeons should be aware of this variation beforeoperations to neck region, because the vertebral arteries may easily be injured due to lack of anterior bony protection of the costalelements. As well as the vertebral artery, the nerve plexus around vertebral artery may also be responsible of some complications due tofailure of this bony protection.Article Citation - WoS: 1Citation - Scopus: 1Abstinence-Related Motivational Engagement Scale: Validity and Reliability in Turkish People(Bilimsel Tip Publishing House, 2018) Yavan, Tulay; Gulesen, Asli; Bebis, HaticeOBJECTIVES: This research aimed to conduct a validity and reliability study of the Turkish version of the abstinence-related motivational engagement (ARME) scale. MATERIALS AND METHODS: This study included 122 people and was administered in a smoking cessation clinic. The sociodemographic-smoking status characteristics questionnaire and the ARME scale were used for data collection. A psycholinguistic language adaptation was performed. In the validity, analyses, content, construct, and criterion-related validities were used. For content validity, expert evaluation was performed. For construct validity, principal component analyses (exploratory factor analyses) were performed. Orthogonal (Varimax) rotation was used to explore multiple factors. The Kaiser-Meyer-Olkin test was used to assess the adequacy of the sample size. For criterion-related validity, we compared the ARME scale points of people who were abstinent and had relapse for smoking at the end of the sixth month. In the reliability analysis, standard deviation (SD) and item analysis, internal consistency, and test-retest methods were used. RESULTS: The four factors explain 58% of the total variance. Items have factor loading between 0.409 and 0.805. When the factor structure of the scale was assessed, the items in each factor group have a factor load of at least 0.40. Due to one-dimensional use of the original scale, it has been decided to maintain this scale in its original form. The ARME scale points of people who quit smoking were statistically higher than the points of people who had relapse at the end of the sixth month. Cronbach's alpha coefficients were between 0.846 and 0.763. Significant and positive correlation was found between the test-retest scale scores. CONCLUSION: The Turkish adaptation of the ARME scale, which was developed for adults who quitted smoking, is an adequately valid and reliable measurement instrument. It is considered that the scale might be used reliably in different cultures as well.Article Citation - WoS: 2Accidental Humor in Consecutive Interpreting: Accidentally Useful Food for Thought(Istanbul Univ, Fac Letters, 2021) Yetkin Karakoç, NihalUnlike humor translation, humor in translation, caused by translation errors, is underresearched in translation studies. Accidental humor, as a subgroup of humor, has been analyzed in translation contexts, but to the best knowledge of the author, not in the interpreting context. This descriptive study, being the first of its kind dealing with the accidental humor in consecutive interpreting, is intended to fill the gap in the verbal manifestations of resources in the English-Turkish interpreting context along with the possible reasons for resources of accidental humor in consecutive interpreting class. As a result of the study, a total of 38 accidentally humorous instances are found. The verbal resources are analyzed and divided into main and sub-categories, and for each, examples from the corpus are discussed. In addition, new linguistic resources were discovered, which may be exclusive to this context. The detected items are by no means meant to be exhaustive, as also stated by the former studies, but nevertheless enables greater understanding about the types and possible causes of accidental humor which may occur during the consecutive interpreting process. Given the dearth of literature on accidental humor in consecutive interpreting, this study may provide some insight for remedial teaching/learning in interpreting studies, as well as linguistics. Future studies may examine, among the others, verbal resources in the simultaneous interpreting context and compare the verbal resources in depth in consecutive with those in simultaneous interpreting.Article Aconitine Impedes Cell Motility in Mda-Mb Breast Cancer Cells(Dokuz Eylul Univ Inst Health Sciences, 2024) Keles, Didem; Sipahi, Murat; Surer, Seniz Inanc; Oktay, GulgunPurpose: Aconitine, a potent alkaloid from Aconitum plants, has shown promising anticancer properties. The aim of the study is to investigate the effects of aconitine on lateral migration, and matrix metalloproteinase (MMP) activity in MDA-MB-231 triple-negative breast cancer cells. Material and Methods: A WST-1 viability assay was conducted to determine the effect of aconitine on the viability of MDA-MB-231 cells. Following treatment with non-cytotoxic doses of aconitine, lateral migration was evaluated through wound healing assays. Additionally, gelatin zymography was conducted to analyze MMP-2 and MMP-9 activity and secretion levels. Results: Aconitine concentrations up to 200 mu M did not significantly affect cell viability for up to 72 hours, whereas higher doses (400-600 mu M) reduced viability in a time-dependent manner. Aconitine at 200 mu M showed a trend towards decreased lateral motility, with a significant reduction at 9 hours post-treatment. Gelatin zymography revealed no alterations in MMP-2 and MMP-9 activity or secretion levels following aconitine treatment. Conclusion: Aconitine demonstrates limited efficacy in modulating the migratory capacity of MDA-MB231 cells and does not affect gelatinase activity. Further investigation into underlying mechanisms is necessary, potentially leading to novel therapeutic strategies for triple-negative breast cancer.Article Citation - WoS: 6Citation - Scopus: 5Acrylamide-Encapsulated Glucose Oxidase Inhibits Breast Cancer Cell Viability(Walter De Gruyter Gmbh, 2020) Rrustemi, Trendelina; Geyik, Oyku Gonul; Ozkaya, Ali Burak; Ozturk, Taylan Kurtulus; Yuce, Zeynep; Kilinc, AliObjectives: Cancer cells modulate metabolic pathways to ensure continuity of energy, macromolecules and redoxhomeostasis. Although these vulnerabilities are often targeted individually, targeting all with an enzyme may prove a novel approach. However, therapeutic enzymes are prone to proteolytic degradation and neutralizing antibodies leading to a reduced half-life and effectiveness. We hypothesized that glucose oxidase (GOX) enzyme that catalyzes oxidation of glucose and production of hydrogen peroxide, may hit all these targets by depleting glucose; crippling anabolic pathways and producing reactive oxygen species (ROS); unbalancing redox homeostasis. Methods: We encapsulated GOX in an acrylamide layer and then performed activity assays in denaturizing settings to determine protection provided by encapsulation. Afterwards, we tested the effects of encapsulated (enGOX) and free (fGOX) enzyme on MCF-7 breast cancer cells. Results: GOX preserved 70% of its activity following encapsulation. When fGOX and enGOX treated with guanidinium chloride, fGOX lost approximately 72% of its activity, while enGOX only lost 30%. Both forms demonstrated remarkable resilience against degradation by proteinase K and inhibited viability of MCF-7 cells in an activity-dependent manner. Conclusions: Encapsulation provided protection to GOX against denaturation without reducing its activity, which would prolong half-life of the enzyme when administered intravenously.Article Acute Abdominal Pain Due To Spontaneous Rupture of the Renal Calyx: Clinical Presentation, Diagnosis and Management(2021) Başok, Erem KaanBackground: Rupture of renal calyces with urinoma, mimicking acute abdomen, is an unusual condition that is mostly caused by distal ureteral stone. Case Presentation: Ultrasonographic evaluation showed right hydronephrosis in a woman who was admitted to our emergency department with persistent severe abdominal pain. A delayed contrast -enhanced computerized tomography (CT) was required to confirm the diagnosis of rupture in symptomatically worsening patient. Among various treatment options conservative treatment was preferred, the patient was recovered, and urinoma was resolved without any complication. Diagnosis and treatment options are discussed. Conclusion: A spontaneous rupture of the urinary system can mimic acute abdomen, and should always be considered in the differential diagnosis of a patient presenting complex symptoms after renal colic. If a definite diagnosis cannot be established by routine imaging modalities, delayed phase contrast- enhanced CT would be helpful in this regard. Conservative treatment with careful monitoring is an option with good results, thus it may obviate the need for surgical intervention in most of the patients.Article Adolescent Health Knowledge of Family Physicians(2023) Aygün, Olgu; Küçükerdem, Halime Seda; Gökdemir, ÖzdenBackground: There are certain life periods when physicians are more cautious with their patients. However, health needs are often disregarded throughout the adolescent era, even though it is a time when fast changes occur in many facets of life, including physical, psychological, cognitive, and social development. This study aimed to contribute to the improvement of adolescent health by measuring the degree of knowledge of family physicians (FPs) on adolescent health services. Material-Method: The was a descriptive-cross-sectional design study. A questionnaire was given to 2200 FPs by e-mail and 344 accepted to participate. The questionnaire had a 13% response rate. Results: Women made up 56.4% of the participants (n=194) and the average age of the participants was 38.77 years (SD: 10.08) (min: 25, max: 80). Two hundred fifteen (62.5%) of the FPs who participated in the survey, had encountered adolescent patients. A statistical correlation was found between having children and the idea that questions should be asked with one-word answers to the target to obtain answers in the adolescent age group (pArticle Citation - WoS: 2Citation - Scopus: 2Adrenomedullin Has No Effect on Segmental Bone Defect Healing but Increases Bone Mineral Density in Rat Model(AVES, 2023) Kaymakoğlu, Mehmet; Ciftci, E.; Korkusuz, P.; Ozdemir, E.; Erden, M.E.; Turhan, E.Objective: This study aimed to investigate the effect of adrenomedullin on the healing of the segmental bone defect in a rat model. Methods: Thirty-six Wistar rats were randomly divided into 6 groups based on follow-up periods and administered a dose of adreno-medullin hormone. In each group, bilaterally, a 2-mm bone defect was created at the diaphysis of the radius. Sodium chloride solution was administered to sham groups 3 times a week for 4 and 8 weeks intraperitoneally. Adrenomedullin was administered to the study groups 3 times a week: 15 μg—4 weeks, 15 μg—8 weeks, 30 μg—4 weeks, and 30 μg—8 weeks, respectively. After euthanasia, the segmental defects were evaluated by histomorphometric [new bone area (NBA)] and microtomographic [bone volume (BV), bone surface (BS), and bone mineral density (BMD)] analyses. Results: Although the 4-and 8-week 15 μg administered study groups had higher NBA values than the other study and control groups, the histomorphometric analysis did not reveal any statistical difference between the control and study groups regarding NBA (P >.05). In microtomographic analysis, BV was higher in the 15 μg 4-week group than 30 μg 4-week group (296.9 vs. 208.5, P =.003), and BS was lower in the 30 μg 4-week group than in the 4-week control group (695.5 vs. 1334.7, P =.005), but overall, no significant difference was found between the control and study groups (P >.05). Despite these minor differences in histomorphometric and microtomographic criteria indicating new bone formation, the BMD values of the 15 μg 8-week study group showed a significant increase compared with the control group (P =.001, respectively). Conclusion: Adrenomedullin positively affected BMD at 15 μg, but this study could not show healing in the segmental defect site at different dose regimens. Further studies are needed to assess its effects on bone tissue trauma. © 2023, AVES. All rights reserved.Article Aerodynamic Analyses of an Integrated Low-Pressure Compression System for Adaptive-Cycle Micro Turbofan Type Jet Engine(2022) Acarer, Sercan; Gürbüz, M TayyipUnmanned Aerial Vehicles (UAVs) are commonly propeller-driven and low-speed. The concept of cost-efficient, much higher speed and longer range applications of micro jet engines was previously addressed such that an existing basic turbojet engine was converted into a single spool turbofan without using additional components of booster and low pressure turbine. Normally, this situation emerges matching problems since two spools are required to adjust the fan speed independently. A simple solution was to use a Continuously Variable Transmission (CVT) gearbox to adjust optimal speed for the fan. As a result, missing of the positive functionality of the booster would lump into the fan root to form a unified low pressure compression system (unified-LPC). Such a unified-LPC demands unique characteristics of having an extreme twist, very high pressure ratio and mass flux at the root section than at the tip section, despite the exact opposite is being enforced due to the wheel speed rise with radius. In light of these challenges, this work aims to investigate detailed aerodynamics of an existing design previously made and reported by the authors. It is shown that, despite the aerodynamic loading contrast throughout the span, the unified-LPC can still have a wide operating range and acceptable off-design aerodynamics. Complementing the previous design- oriented work, this paper aims to provide guidelines for such unified compression systems.Article Citation - WoS: 1Citation - Scopus: 1Aesthetic and Cultural Approach To the Change in the Making Techniques of Karagoz Figures(Istanbul Univ, Research Inst Turkology, Dept Art History, 2021) Öngen Corsini, Duygu EbruKaragoz developed as a unique culture in Anatolian lands. Despite many controversies about how Karagoz came into existence, there is a consensus that it emerged in the 16th century. Figures, as cultural objects, have production methods and techniques interwoven with the doctrines of the past. Today, figure-making for different purposes, inherited from the past, is present in Karagoz figure art. The aesthetic reflections, technique, and material harmony of the figures for show purposes must carry the cultural essence of Karagoz. This study examines museum collections and exhibitions, interviews with Karagoz masters, and a data analysis from an academic perspective. Considering these factors, it becomes clear that the training of masters for figure-making art is significant. Long-term training organized by institutions will contribute to this art and might be beneficial for good examples to reach the audience. Transferring the figures to future generations while preserving their cultural essence, making them in a suitable technique, and aesthetic understanding synthesized with modern techniques; will also contribute to the survival of this art.Article Afet Haberi Başlıklarının Çevirisinde Tutumsal Anlam Kaymaları: Türk Medyasındaki Söylemin Yanmetinsel Analizi(2025) Şener, OlcayBu çalışma, komşu ülke Yunanistan’da meydana gelen bir afetin, Türk medyasında çeviri yoluyla nasıl temsil edildiğini ortaya koymayı amaçlamaktadır. Bu amaç doğrultusunda, BBC News, Euronews, CNN ve The Independent adlı dört farklı medya kuruluşundan seçilen 12 İngilizce ve Türkçe haber başlığı analiz edilmiştir. Haber başlıkları yanmetinsel unsurlar olarak, Değerlendirme Kuramı’nın (Appraisal Theory) (Martin & White, 2005) Tutum (Attitude) dizgesi çerçevesinde nicel ve nitel yöntemlerle incelenmiştir. Her iki dildeki haber başlıklarının tutumsal anlam kaymaları, Tutum dizgesinin üç alt ulamı olan duygulanım (affect), yargı (judgement) ve takdir (appreciation) bağlamında analiz edilmiştir. Nicel analiz, iki dil arasında anlam kaymaları açısından sınırlı bir fark olduğunu gösterirken; karşılaştırmalı nitel analiz ise, tutumsal anlamlarda daha belirgin kaymalar olduğunu ortaya koymuştur. Özellikle haber başlığı çevirilerinin duygulanım (affect) kategorisinde duygusal tepkileri yoğunlaştırdığı; takdir (appreciation) kategorisinde ise kültürel-estetik değerleri zayıflattığı gözlemlenmiştir. Öte yandan, yargı (judgement) kategorisinin ideolojik motivasyonlarla şekillendiği gözlemlenmiştir. Ayrıca, her iki dilde de hükümet gücüne yapılan vurgunun artırılması açısından bir tutarlılık saptanmıştır. Bulgular, anlam kaymalarının her zaman tarafsızlık hedefiyle gerçekleşmediğini; bu kaymaların etkisinin, çevirinin üretildiği sosyo-politik ve ekonomik bağlamla ilişkili olabileceğini göstermektedir.Article Citation - Scopus: 1Affecting Factors in Medication Adherence in Kidney Transplant Recipients(Aves, 2023) Ordin, Yaprak Sarigol; Karayurt, Ozgul; Ertan, Nermin; Edeer, Aylin Durmaz; Yildiz, SerkanObjective: This study aimed to determine the risk factors related to immunosuppressive medication adherence in kidney transplant recipients. Methods: The study adopted a retrospective design. It was carried out on 208 kidney transplant recipients. The social cognitive theory was used for understanding and addressing the issues of nonadherence to immunosuppressive medication. Data were collected with a self-reported-Immunosuppressant Therapy Adherence Scale and biological assays. Descriptive analyses and logistic regression were used to analyze data. Results: According to the self-reported assessment, medication adherence of the patients receiving transplants from live donors was 0.503 times lower than that of the patients receiving transplants from deceased donors. The biological assays did not show any affecting factors in medication adherence. Conclusion: The results of the study showed the importance of combining methods to assess medication adherence. In the self-reported assessment, live donor transplantation was found to negatively affect medication adherence. Turkiye is the country with the highest number of kidney transplantations from live donors in the world. Health professionals must be more careful in assessing medication adherence after live donor transplantations.Article Ageless Wisdom: a Cross-Cultural Study on Enhancing Life Satisfaction Through Skills Promotion Among Older Adults(2024) Adele Gaia De Stefani; Burçin Önder; Kaygın, Hüseyin; Ulus, İhsan Çağatay; Ratkowska-Pasikowska, Justyna; Ertürk, Nesrin OruçThis article explores the pervasive issue of ageism and its detrimental effects on the elderly population. Ageism or the prejudice and discrimination against older adults based on their age, can have significant impact on their well-being and life satisfaction. However, the article also delves into the potential positive effects of continuous learning on reducing ageism and enhancing the life satisfaction of the elderly. As a proactive approach, lifelong learning presents an opportunity for the elderly to challenge stereotypes, remain engaged in society, and foster personal growth. This study highlights how training and educational programs can empower older adults, instilling a sense of purpose and accomplishment, leading to a more fulfilled and satisfying life in their later years. The main purpose was to investigate how continuous learning affects the lives and life satisfaction perception of elderly people over the age of 65 from Greece, Hungary, Italy, Poland and Turkey after one week and 25 hours of technology, art and psychotherapy trainings that are believed to support them in every aspect of life.Article Aile Hekimlerinin Sağlıklı Yaşam Biçimi Davranışlarının ve Klinik Uygulamalarında Yaşam Biçimi Tıbbının Değerlendirilmesi(Galenos Publishing House, 2025) Semin, Ilgi; Kazdağlı, Hasan; Gökdemir, ÖzdenAmaç: Bu çalışmanın amacı, aile hekimlerinin sağlıklı yaşam biçimi davranışlarını değerlendirmek ve klinik uygulamalarında yaşam biçimi tıbbına yönelik katılımlarını incelemektir. Yöntemler: Temmuz 2018 ile Ağustos 2019 tarihleri arasında aile hekimlerinden veri toplamak amacıyla çevrimiçi bir anket geliştirildi. Tanımlayıcı ve korelasyonel bir araştırma deseni kullanıldı. Çalışmada uygulanan anket, “katılımcıların kişisel bilgileri” ve “Sağlıklı Yaşam Biçimleri Davranış Ölçeği-II”i içermektedir. Kesitsel bir çalışma olarak tasarlanan bu araştırmada, örneklem kolayda örnekleme metodu ile sekiz ülkeden belirlenmiştir, ve anketler katılımcılara elektronik ortamda uygulanmıştır. Katılımcılara anketin süresi, veri saklama işlemleri, saklama süresi, araştırmacıların kimliği ve çalışmanın amacı hakkında bilgi verilmiştir. Bulgular: Çalışmaya 131 aile hekimi katılmış olup, erkek katılımcı oranı daha yüksek bulunmuştur. Sigara içme sıklığının Türk aile hekimleri arasında anlamlı derecede yüksek olduğu tespit edilmiştir (p=0,013). Ancak, ölçek toplam puanı veya altı boyutta alınan puanlar açısından aile hekimleri arasında istatistiksel olarak anlamlı bir fark bulunmamıştır. Sonuç: Çoğu aile hekimi, bu alanda daha fazla eğitim almak istediklerini belirtmiştir, bu da tıp fakültelerinin müfredatına eğitim müdahalelerin dahil edilmesi gerekliliğini göstermektedir. Ayrıca, iyi yapılandırılmış web tabanlı kitlesel çevrimiçi kurslar, aile hekimlerinin sağlıklı yaşam biçimi davranışları ve yaşam biçimi tıbbı uygulamalarına yönelik eğitim gereksinimlerini karşılamada etkili bir çözüm olabilir.Article Alışveriş Mekanlarında Aydınlatmanın Ürün Renk Algısı ve Kullanıcı Memnuniyeti Üzerine Etkileri(2022) Dilgen, Ozge; HASIRCI, DenizAlışveriş mekani aydınlatma uygulamalarında ışık kaynağının renk özellikleri, kullanıcı memnuniyetini etkileyen en önemli faktörlerin başında gelmektedir. Düşük renksel geriverim değerine sahip bir aydınlatma tasarımı ve uygun olmayan bir renk sıcaklığı, ürünün renk algısında farklılık yaratarak müşterilerin satın alma kararını etkileyebilir veya ürünün iade edilmesi ile sonuçlanan memnuniyetsizliğe neden olabilir. Bu çalışmada, aydınlatmanın ürün renk algısı üzerindeki etkisi ve bu duruma bağlı müşteri memnuniyeti/ memnuniyetsizliğinin değerlendirilmesi amaçlanmıştır. Bu amaç doğrultusunda, İzmir, Türkiye’de bulunan zincir bir perakence mağazasında seçilen ürünlerin renkleri mağazanın üç farklı kilit alanında incelenmiş ve gün ışığındaki renkleri ile karşılaştırılmıştır. Ayrıca, sergilenen ürünün renk algısındaki farklılıklar ile kullanıcı memnuniyeti arasındaki ilişkiyi tartışmak için müşterilere bir anket uygulanmıştır. Toplanan veriler, müşterilerin mağaza içerisindeyken renk farklılıklarını fark etmeseler de, satın aldıktan sonra böyle bir deneyim yaşamaları durumunda ürünün iade edilmesiyle sonuçlanabileceğini göstermektedir. Çalışmanın sonucunda, kullanıcıların ürünü tasarımcının amaçladığı renge olabildiğince yakın algılamasını sağlamak için perakende mağaza tasarımcıları ve aydınlatma mühendislerinin işbirliği yapması önerilmiştirArticle Alışveriş Merkezleri Hizmetlerinde Engeller ve Savunmasızlık Kaynakları: Engelli Bireylerin Bakış Açısı(2023) Köstepen Özbek, Kübra Göksu; Yumurtacı Hüseyinoğlu, Işık Özge; Oflaç, BengüBu çalışmanın amacı, engelli bireylerin alışveriş merkezlerine eri- şimde ve alışveriş merkezinin içerisinde tecrübe ettikleri savunma- sızlık kaynaklarını araştırmaktır. Görme ve ortopedik engelleri olan katılımcılarla yapılan 20 yarı yapılandırılmış mülakattan elde edilen bulgular sunulmaktadır. Bulgular, gelişmekte olan bir pazarda engelli bireylerin karşılaştığı fiziksel engellere, sosyal ve duygusal engelle- re ve bunların sonucunda ortaya çıkan doğal, durumsal ve patojenik savunmasızlıklara işaret etmektedir. Savunmasızlık kaynağı, karşılık gelen savunmasızlık türüyle ilişkilendirilmektedir. Örneğin; yolla il- gili fiziksel savunmasızlık kaynağı, doğal ve durumsal savunmasızlık türü altında değerlendirilirken, insan kaynaklı duygusal savunmasız- lık kaynağı, kalıtsal ve patojenik savunmasızlık altında incelenmek- tedir. Bu çalışma, alışveriş merkezi erişimi ve içerisindeki hareket yetkinliğini kapsayarak, geniş bir perspektif sunarak mevcut literatüre katkıda bulunmayı amaçlamaktadır. Bunun yanı sıra, savunmasızlık literatürüne de katkı sağlamakta ve seçilen içerikteki savunmasızlık kaynaklarına yönelik daha yüksek bir farkındalık düzeyi oluşturmayı amaçlamaktadır.

